Lethal outbreak of disease associated with feline calicivirus infection in cats

Recently, in the USA, virulent mutants of feline calicivirus (FCV) have been identified as the cause of a severe and acute virulent systemic disease, characterised by jaundice, oedema and high mortality in groups of cats. This severe manifestation of FCV disease has so far only been reported in the USA. However, in 2003, an outbreak of disease affected a household of four adult cats and an adult cat from a neighbouring household in the UK. Three of the adult cats in the household and the neighbouring cat developed clinical signs including pyrexia (39.5 to 40.5 degrees C), lameness, voice loss, inappetence and jaundice. One cat was euthanased in extremis, two died and one recovered. A postmortem examination of one of the cats revealed focal cellulitis around the right hock and right elbow joints. The principal finding of histopathological examinations of selected organs from two of the cats was disseminated hepatocellular necrosis with mild inflammatory infiltration. Immunohistology identified FCV antigen in parenchymal and Kupffer cells in the liver of both animals and in alveolar macrophages of one of them. In addition, calicivirus-like particles were observed by electron microscopy within the hepatocytes of one cat. FCV was isolated from two of the dead cats and from the two surviving cats. Sequence analysis showed that they were all infected with the same strain of virus, but that it was different from strains of FCV associated with the virulent systemic disease in cats in the USA. The outbreak was successfully controlled by quarantine in the owner's house.     

Hairy shaker disease of lambs: Further studies on acquired immunity,abortion and effects on foetal growth

The one-stage prothrombin times of 100 lambs from ten different farms varied from 13 to 24 seconds with a mean of 16.6 seconds. The extent and severity of subcutaneous haemorrhagic speckling of carcases was assessed in 775 animals from the same farms and the prevalence of this lesion was similar to that found at the same works during the 1977/78 season. The means of both one-stage prothrombin times and speckling varied significantly between groups of Iambs from different farms but there was no statistical association between the prevalence of speckling and the one-stage prothrombin times.     

How landscape ecology can promote the development of sustainable landscapes in Europe: the role of the European Association for Landscape Ecology (IALE-Europe) in the twenty-first century

In Europe, landscape research has a long tradition of drawing on several disciplines. ‘National schools’ of landscape research developed, which were related to the characteristic landscapes found in the different countries and to specific linguistic meanings and legal traditions when using landscape related concepts. International co-operation demands a certain harmonization of these concepts for better mutual understanding. The 2000 European Landscape Convention provided an important momentum to rethink research, policy and management of landscapes from the perspective of sustainable development and participatory planning. Landscape ecology as a transdisciplinary science with a dynamic and holistic perspective on landscape offers a great potential for an integrative approach. The specificity of the European landscape research rests on its long history and on integration based on the great diversity of the landscapes, characterised by an intimate relationship between the varied natural environment and the different cultural traditions which define the identity of countries, regions and people. Within a unified Europe, with increasing international and trans-border co-operation and increasing common environmental problems, the creation of a specific European Association for Landscape Ecology (IALE-Europe), in addition to the existing international association and its national chapters, became justified by the need for a collaborative endeavour to address the specific problems of landscapes in Europe and to stimulate co-operation between landscape ecologists in research, education and practice.     

Heritability and transmission analysis of necrotizing meningoencephalitis in the Pug

Necrotizing meningoencephalitis (NME) in the Pug is an invariably fatal disease with an early age of onset whose cause remains unknown. Breed predilection strongly suggests genetic component(s), and viral etiology proves negative in studied cases. The current study was undertaken as the first analysis of the heritable component(s) involved in NME in the Pug. Complete medical records, individual characteristics, and pedigree information were collected for 58 affected dogs with data pertaining to 4698 dogs analyzed. A high inbreeding coefficient with differences across gender and significant differences across coat color classes and variable expression was evident. Median onset age was 19 months and median survival time 23 days. Screening for herpes-, adeno-, and parvoviruses was negative. The data demonstrate a strong familial inheritance of NME in the Pug. This investigation provides parameters of disease from the largest Pug NME cohort analyzed to date and offers evidence of previously unrecognized familial inheritance.     

Designer repellents: combining olfactory, visual or taste cues with a secondary repellent to deter free-ranging house sparrows from feeding

BACKGROUND: Repellents may prevent bird pests from eating crops or protect non‐target birds from eating harmful substances. The feeding behaviour of free‐ranging house sparrows (Passer domesticus) presented with wheat treated with the secondary repellent anthraquinone (AQ), paired with visual and/or olfactory and taste cues, was recorded in a series of trials. The aim was to determine the suitability of repellent combinations for preventing birds from consuming pest baits. RESULTS: Anthraquinone significantly reduced wheat consumption. The addition of cinnamon oil did not reduce consumption further, but the addition of either a blue colour or d‐pulegone enhanced repellency. Green wheat was consumed more than blue wheat. In a multichoice test, the sparrows did not differentiate between low and high concentrations of AQ on blue‐dyed wheat. With treatments on separate tables, the higher concentration was more repellent. Additional olfactory/gustatory cues palatable to pest mammals did not make the AQ‐treated wheat more or less acceptable to sparrows. AQ‐treated blue wheat with/without cinnamon oil was more repellent than green wheat with cinnamon oil, a colour/odour combination typically used for pest baits in New Zealand. CONCLUSIONS: These data demonstrate the potential of combining the secondary repellent AQ with additional salient cues for modifying the feeding behaviour of sparrows. Copyright © 2011 Society of Chemical Industry