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J.J. Cooper S.J. Schatzberg K.M. Vernau B.A. Summers B.F. Porter S. Siso B.D. Young J.M. Levine 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2014,28(1):198-203
Background
Canine necrotizing meningoencephalitis (NME) is a fatal, noninfectious inflammatory disease of unknown etiology. NME has been reported only in a small number of dog breeds, which has led to the presumption that it is a breed‐restricted disorder.Hypothesis/Objectives
Our objective was to describe histopathologically confirmed NME in dog breeds in which the condition has not been reported previously and to provide preliminary evidence that NME affects a wider spectrum of dog breeds than previously reported.Animals
Four dogs with NME.Methods
Archives from 3 institutions and from 1 author''s (BS) collection were reviewed to identify histopathologically confirmed cases of NME in breeds in which the disease has not been reported previously. Age, sex, breed, survival from onset of clinical signs, and histopathologic findings were evaluated.Results
Necrotizing meningoencephalitis was identified in 4 small dog breeds (Papillon, Shih Tzu, Coton de Tulear, and Brussels Griffon). Median age at clinical evaluation was 2.5 years. Histopathologic abnormalities included 2 or more of the following: lymphoplasmacytic or histiocytic meningoencephalitis or encephalitis, moderate‐to‐severe cerebrocortical necrosis, variable involvement of other anatomic locations within the brain (cerebellum, brainstem), and absence of detectable infectious agents.Conclusions and Clinical Importance
Until now, NME has only been described in 5 small dog breeds. We document an additional 4 small breeds previously not shown to develop NME. Our cases further illustrate that NME is not a breed‐restricted disorder and should be considered in the differential diagnosis for dogs with signalment and clinical signs consistent with inflammatory brain disease. 相似文献35.
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L. Hoagland L. Carpenter-Boggs J.P. Reganold M. Mazzola 《Soil biology & biochemistry》2008,40(7):1689-1697
Biologically based weed control strategies are needed in organic and low-input systems. One promising practice is the application of Brassicaceous seed meal (BSM) residue, a byproduct of biodiesel production. When applied as a soil amendment, BSM residue has exhibited potential bioherbicide activity. In this study, tree fruit orchard soils were treated with various BSMs and the impact of Pythium on weed suppression was examined in field and greenhouse studies. Although weed control obtained in response to Brassicaceous residue amendments has been repeatedly attributed solely to release of allelopathic phytochemicals, multiple lines of evidence acquired in these studies indicate the involvement of a microbiological component. Reduced weed emergence and increased weed seedling mortality were not related to BSM glucosinolate content but were correlated with significant increases in resident populations of Pythium spp. in three different orchard soils. Seed meal of Brassica juncea did not amplify resident Pythium populations and did not suppress weed emergence. Application of Glycine max SM did stimulate Pythium spp. populations and likewise suppressed weed emergence. Application of a mefenoxam drench to Pythium-enriched soil significantly reduced weed suppression. These studies indicate that a microbial mechanism is involved in SM-induced weed suppression and that selective enhancement of resident pathogenic Pythium spp. can be utilized for the purpose of weed control. 相似文献
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Summary The development of high temperature-tolerant wheat (Triticum aestivum L.) germplasm is necessary to improve plant productivity under high-temperature stress environments. The quantification of high temperature tolerance and the characterization of its genetic control are necessary for germplasm enhancement efforts. This study was conducted to determine the genetic control of acquired high temperature tolerance in common bread wheat cultivars. Reduction of 2,3,5-triphenyltetrazolium chloride (TTC) by heat-stressed seedling leaves was used as a quantitative measure to characterize acquired high temperature tolerance. Eleven-day-old seedlings of 20 F1 progeny produced through a complete 5×5 (Payne, Siouxland, Sturdy, TAM W-101, and TAM 108) diallel mating design were acclimated at 37° C for 24 hours, followed by a 2-hour incubation at 50° C. Under these test conditions, acquired high temperature tolerance ranged from a high of 75.7% for the genotype TAM W-101 × TAM 108, to a low of 37.3% for the genotype Payne × Siouxland. Partitioning of genotypic variance revealed that only the general combining ability component effect was statistically highly significant, accounting for 67% of the total genotypic variation. These results suggest that enhancing the level of high temperature tolerance in wheat germplasm is feasible utilizing existing levels of genetic variability and exploiting additive genetic effects associated with high temperature tolerance.Contribution of the Texas Tech College of Agric. Sci. Journal no T-4-386. This work was supported by USDA specific agreement No. 58-7MNI-6-114 from the Plant Stress and Water Conservation Laboratory, USDA-ARS, Lubbock, Texas, USA 相似文献
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