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301.
Double Health Risk in Arsenic Contaminated Drinking Water – Evidence of Enhanced Alpha Radioactivity
Dipak Ghosh Argha Deb Kanchan Kumar Patra Rosalima Sengupta Sukumar Bera 《Water, air, and soil pollution》2008,187(1-4):81-87
The presence of alpha emitting radionuclides in the environment assumes importance since they are found to be carcinogenic. This paper reports the results of an exhaustive and systematic measurement of alpha radioactivity using solid state nuclear track detector (SSNTD) in drinking water in different parts of India covering the entire Ganges Basin – West Bengal, Bihar and Uttar Pradesh where arsenic contamination is severe. The alpha activity in the samples was found in the range of 8 to 800 Bq/l in West Bengal, 90 to 1,000 Bq/l in Uttar Pradesh and 60 to 1,000 Bq/l in Bihar – much higher alpha activity value than MCL value given by US EPA. The concentration of alpha activity has a positive correlation with that of arsenic. 相似文献
302.
Polymorphism in 5′ untranslated region of heat‐shock protein 70 gene as marker of post‐partum anoestrus in Murrah buffaloes
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R Kumar M Ghosh N Kumar AK Balhara M Gupta RK Sharma I Singh 《Reproduction in domestic animals》2017,52(3):505-512
The enormous production potential of buffaloes has never been accomplished due to various reproductive insufficiencies. Among them, post‐partum anoestrus, a multifactorial disorder, is predominant but any genetic association is yet to be established. This study focused to identify novel polymorphisms in heat‐shock protein 70 (HSP70) gene and its possible association with post‐partum anoestrus in Murrah buffaloes. A 579‐bp fragment from 5′ untranslated region of HSP70 gene was amplified by polymerase chain reaction from blood genomic DNA of 614 animals maintained under similar management conditions. In phase‐I experiment, custom sequencing and restriction enzyme (RE) digestion of the amplified fragment were performed in 40 buffaloes with similar post‐partum oestrous conditions over previous consecutive three or more gestations—20 animals each showing post‐partum anoestrus (>120 days after parturition) and normal cyclicity (<65 days after parturition). While in phase‐II experiment, herd screening by RE analysis was performed in remaining 574 animals. Four transversions at T‐75G, C+31G, T+38G and C+97A and three transition mutations at T‐153C, T+33C and A+44G positions were observed. Polymorphism at T+38G site revealed significant (p < .05) variation, where homozygous G was present only in post‐partum anoestrous animals while nucleotide T was present randomly in both groups of phase‐I animals whereas phase‐II experiments revealed homozygous G in 55 animals. Regression analysis in relation to average post‐partum interval against genotypic frequencies at T+38G also depicted significant association. HSP70 gene polymorphism at T+38G position can therefore be used as genetic marker for excluding probable post‐partum anoestrous buffaloes from herd for breeding programmes. 相似文献
303.
Avijit Ghosh Brahma Swaroop Dwivedi Dipak Ranjan Biswas Mahesh Chandra Meena Abhijit Sarkar 《Archives of Agronomy and Soil Science》2018,64(9):1290-1301
The aim of this study was to understand impacts of long-term (43 years) fertilization on soil aggregation, N accumulation rates and δ15N in surface and deep layers in an Alfisol. Soil samples from seven treatments were analysed for N stocks, aggregate-associated N in 0–30 cm and the changes in δ15N in 0–90 cm depths. The treatments were: unfertilized control (control); recommended N dose (N); recommended N and phosphorus doses (NP); recommended N, P and potassium doses (NPK); 150% of recommended N, P and K doses (150% NPK); NPK + 10 Mg FYM ha?1 (NPK + FYM) and NPK + 0.4 Mg lime ha?1 (NPK + L). Results revealed that plots under NPK + FYM had ~39% higher total N concentrations than NPK + L in 0–30 cm soil layers. In NPK + L, macro-aggregates had 35 and 11% and microaggregates had 20 and 9% lower δ15N values than NPK + FYM in 0–15 and 15–30 cm soil layers, respectively. However, plots receiving NPK + FYM had ~39% greater deep soil (30–90 cm) N accumulation than NPK + L. These results would help understanding N supplying capacity by long-term fertilization and assist devising N management strategies in sub-tropical acidic Alfisols. 相似文献
304.
A Non‐Reciprocal Autosomal Translocation 64,XX,t(4;10)(q21;p15) in an Arabian Mare with Repeated Early Embryonic Loss
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S Ghosh PJ Das F Avila BK Thwaits BP Chowdhary T Raudsepp 《Reproduction in domestic animals》2016,51(1):171-174
Balanced autosomal translocations are a known cause for repeated early embryonic loss (REEL) in horses. In most cases, carriers of such translocations are phenotypically normal, but the chromosomal aberration negatively affects gametogenesis giving rise to both genetically balanced and unbalanced gametes. The latter, if involved in fertilization, result in REEL, whereas gametes with the balanced form of translocation will pass the defect into next generation. Therefore, in order to reduce the incidence of REEL, identification of translocation carriers is critical. Here, we report about a phenotypically normal 3‐year‐old Arabian mare that had repeated resorption of conceptuses prior to day 45 of gestation and was diagnosed with REEL. Conventional and molecular cytogenetic analyses revealed that the mare had normal chromosome number 64,XX but carried a non‐mosaic and non‐reciprocal autosomal translocation t(4;10)(q21;p15). This is a novel translocation described in horses with REEL and the first such report in Arabians. Previous cases of REEL due to autosomal translocations have exclusively involved Thoroughbreds. The findings underscore the importance of routine cytogenetic screening of breeding animals. 相似文献