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111.
Dayoung Oh Siheon Lee Seungji Kim Sangkyung Choen Mincheol Choi Junghee Yoon 《Veterinary radiology & ultrasound》2019,60(1):28-37
Bronchomalacia and bronchial collapse are important causes of chronic coughing in dogs. The current reference standard diagnostic tests for these problems are flexible bronchoscopy and biopsy. Previous human studies have also supported inspiration/expiration computed tomography (CT) as a diagnostic test. The current prospective, pilot study aimed to determine whether inspiration/expiration CT is also a feasible test for quantifying bronchial collapsibility in dogs. Thoracic CT images were acquired using a 64‐row multidetector CT for 10 healthy Beagle dogs during maximal inspiration and expiration. For each scan, one observer measured transverse sectional areas of the mainstem and lobar bronchi, and the dorsal and ventral segmental bronchi of the left cranial lobar bronchus. Diameters for each bronchus were also measured in transverse, sagittal, and dorsal planes. Bronchial collapsibility (%) was calculated as the difference between inspiration/expiration transverse sectional areas divided by the inspiration transverse sectional areas. Mean bronchial collapsibility of all bronchi was 38.20 ± 15.17%. A collapsibility of over 50% was found in the dorsal (n = 7) and ventral (n = 4) segmental bronchi of the left cranial lobar bronchus, and the left caudal (n = 5) and right middle (n = 2) lobar bronchus. Bronchial collapsibility measurements were greater in the dorsal and ventral segmental bronchi of the left cranial lobar bronchus and the left caudal lobar bronchus (P < 0.001). Findings supported inspiration/expiration CT as a modality to noninvasively assess bronchial collapse in dogs and a bronchial collapsibility value greater than 50% for detecting pathologic bronchial collapse in clinically affected dogs. 相似文献
112.
Eunseok Jeong Rommel M. Tan Hyunsuk Oh Kyungeun Kim Yeji Choi Min‐su Kim Namsoo Kim Kichang Lee 《Veterinary radiology & ultrasound》2016,57(6):E67-E70
A 9‐year‐old intact female mixed breed dog was presented for mammary gland tumor surgery, and preoperative radiographs showed a tubular soft tissue opacity mass with multifocal mineralization in the caudoventral abdominal cavity. Subsequent ultrasonography demonstrated uterine dilation with echogenic fluid and endometrial acoustic shadowing consistent with mineralization. Resection of mammary gland tumors and ovariohysterectomy were performed. Pyometra was diagnosed on cytologic examination of uterine fluid. Histopathology of the uterine tissue confirmed a diagnosis of cystic endometrial hyperplasia with uterine mineralization. 相似文献
113.
Feng DL Lu DH Shen KM Kim C Eisaki H Damascelli A Yoshizaki R Shimoyama J Kishio K Gu GD Oh S Andrus A O'Donnell J Eckstein JN Shen Z 《Science (New York, N.Y.)》2000,289(5477):277-281
We report that the doping and temperature dependence of photoemission spectra near the Brillouin zone boundary of Bi(2)Sr(2)CaCu(2)O(8+delta)exhibit unexpected sensitivity to the superfluid density. In the superconducting state, the photoemission peak intensity as a function of doping scales with the superfluid density and the condensation energy. As a function of temperature, the peak intensity shows an abrupt behavior near the superconducting phase transition temperature where phase coherence sets in, rather than near the temperature where the gap opens. This anomalous manifestation of collective effects in single-particle spectroscopy raises important questions concerning the mechanism of high-temperature superconductivity. 相似文献
114.
115.
Choi JH Lee CH Hwang IK Won MH Seong JK Yoon YS Lee HS Lee IS 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2007,69(11):1131-1136
Microglia are evenly distributed throughout the brain parenchyma. They respond rapidly to a variety of alterations in the microenvironment of the brain and act as sensors for pathological events in the brain. In the present study, we investigated the age-dependent changes in the immunoreactivity and protein level of ionized calcium-binding adapter molecule 1 (Iba-1), a microglial marker, in the CA1 region of the gerbil hippocampus. Iba-1 immunoreactive microglia were detected in the hippocampal CA1 region of the postnatal month 1 (PM 1) group. Iba-1 positive microglia were morphologically inactive between the PM 1 and PM 12 stages. Some Iba-1 immunoreactive microglia were present in the active form in the hippocampal CA1 region of the PM 18 and PM 24 groups. The Iba-1 protein levels in hippocampal CA1 homogenates were decreased in the PM 1 through PM 6 groups and increased in an age-dependent manner thereafter. These results suggest that Iba-1 immunoreactive microglia in the active form were detected in the hippocampal CA1 region in the PM 18 and PM 24 groups. This result may be associated with an age-dependent susceptibility to neurodegenerative diseases associated with the hippocampus. 相似文献
116.
Bao Le Jong-Am Shin Man-Gu Kang Sangmi Sun Seung Hwan Yang Gyuhwa Chung 《Aquaculture International》2018,26(4):937-946
Light-emitting diode (LED) technology offers potential energy-efficient light sources for algal aquaculture. In this study, the growth rate and ulvan yield of Ulva pertusa used for broad commercial applications were enhanced in vitro. To investigate the response of Ulva to LEDs, algae were grown under white fluorescent, pure primary color LED, and mixed LED lights for 28 days. Ulva sp. under blue LED and white fluorescent light showed higher specific growth rate (SGR, 12% day?1) than other light sources, while the growth under mixed red-blue LED light was lower than that under white fluorescent lighting. Despite the differences in alga growth under LEDs and white fluorescent light, few differences are observed in N and P content among algae grown under any light source. U. pertusa showed tissue nitrogen and ulvan contents in the ranges of 4.4–6.7% and 20.4–25.1%, respectively, under all LED light treatments. The ulvan extracted from algae under blue LED showed high levels of antioxidant activity measured with 2,2-diphenylpicrylhydrazyl (DPPH) radical and hydrogen peroxide. Moreover, the ulvan obtained under different lights showed different monosaccharide compositions. Based on these results, LEDs should be considered as the main light sources for indoor seaweed cultivation. 相似文献
117.
Jun-Hwan Kim Hee-Ju Park Kyeong-Wook Kim In-Ki Hwang Do-Hyung Kim Chul Woong Oh Jung Sick Lee Ju-Chan Kang 《Fish physiology and biochemistry》2017,43(5):1421-1431
Juvenile sablefish, Anoplopoma fimbria (mean length 15.5 ± 1.9 cm, mean weight 68.5 ± 4.8 g), were used to evaluate the effects on growth, oxidative stress, and non-specific immune responses by changes of water temperature (8, 10, 12, 14, 16, 18, and 20 °C) and salinity (100 (35.0), 90 (31.5), 80 (28.0), 70 (24.5), 60 (21.0), 50 (17.5), and 40% (14.0) (‰)) for 4 months. The growth performance was significantly increased at the temperature of 12 and 14 °C, and the feed efficiency was notably decreased at the temperature of 18 °C. The growth performance and feed efficiency were also significantly decreased at low salinity. The antioxidant responses such as superoxide dismutase and catalase were significantly increased by the high temperature and decreased by the low salinity. The immune responses such as lysozyme and phagocytosis were elevated by the temperature of 18 °C and decreased by the salinity of 50%. The results of this study indicate that the growth performance of juvenile sablefish, A. fimbria, is influenced by the temperature and salinity, and the excessive temperature and salinity levels can affect the antioxidant and immune responses. 相似文献
118.
Hye-Won Yang Seyeon Oh Dong-Min Chung Minyoung Seo Shin Jae Park You-Jin Jeon Kyunghee Byun BoMi Ryu 《Marine drugs》2022,20(5)
The in vitro capacity of Ishige okamurae extract (IO) to improve impaired muscle function has been previously examined. However, the mechanism underlying IO-mediated muscle protein metabolism and the role of its component, Ishophloroglucin A (IPA), in mice with dexamethasone (Dexa)-induced muscle atrophy remains unknown. In the present study, we evaluated the effect of IO and IPA supplementation on Dexa-induced muscle atrophy by assessing muscle protein metabolism in gastrocnemius and soleus muscles of mice. IO and IPA supplementation improved the Dexa-induced decrease in muscle weight and width, leading to enhanced grip strength. In addition, IO and IPA supplementation regulated impaired protein synthesis (PI3K and Akt) or degradation (muscle-specific ubiquitin ligase muscle RING finger and atrogin-1) by modulating mRNA levels in gastrocnemius and soleus muscles. Additionally, IO and IPA upregulated mRNA levels associated with muscle growth activation (transient receptor potential vanilloid type 4 and adenosine A1 receptor) or inhibition (myostatin and sirtuin 1) in gastrocnemius and soleus muscle tissues of Dexa-induced mice. Collectively, these results suggest that IO and IO-derived IPA can regulate muscle growth through muscle protein metabolism in Dexa-induced muscle atrophy. 相似文献
119.
Young-Mi Oh Dean L. Hesterberg Paul V. Nelson 《Communications in Soil Science and Plant Analysis》2016,47(6):753-760
The objective was to evaluate phosphate desorption characteristics of synthetic hematite, goethite, and allophane and commercial alumina after loading at maximum adsorbed phosphate levels to determine their potential to release phosphate at a constant, low level to sustain plant growth in soilless media and reduce phosphate leaching. Desorption isotherms were measured at pH 6.4 ± 0.1 using a continuously stirred-flow reactor. The time period during which dissolved phosphate was maintained within the range of 5–0.2 mg·L?1 phosphate-P decreased in the order: allophane (12.4 d) > alumina (4.6 d) > goethite (3.6 d) > hematite (1.9 d). Allophane released the most phosphate during the desorption process (40% of maximum adsorbed phosphate; 12.7 mg?g?1) followed by alumina and goethite (19–20%; ≈2.5 mg?g?1) and lastly hematite (5%; 0.1 mg?g?1). Allophane demonstrated the greatest potential as a phosphate-charged source for soilless root media, in amount and duration of phosphate release. 相似文献
120.
Ji-Su Ahn Ye Young Shin Su-Jeong Oh Min-Hye Song Min-Jung Kang So Yeong Park Phuong Thao Nguyen Dang Khoa Nguyen Hyoung Kyu Kim Jin Han Elena A. Vasileva Natalia P. Mishchenko Sergey A. Fedoreyev Valentin A. Stonik Yoojin Seo Byung-Chul Lee Hyung-Sik Kim 《Marine drugs》2022,20(11)
The diverse therapeutic feasibility of the sea urchin-derived naphthoquinone pigment, Echinochrome A (Ech A), has been studied. Simple and noninvasive administration routes should be explored, to obtain the feasibility. Although the therapeutic potential has been proven through several preclinical studies, the biosafety of orally administered Ech A and its direct influence on intestinal cells have not been evaluated. To estimate the bioavailability of Ech A as an oral administration drug, small intestinal and colonic epithelial organoids were developed from mice and humans. The morphology and cellular composition of intestinal organoids were evaluated after Ech A treatment. Ech A treatment significantly increased the expression of LGR5 (~2.38-fold change, p = 0.009) and MUC2 (~1.85-fold change, p = 0.08). Notably, in the presence of oxidative stress, Ech A attenuated oxidative stress up to 1.8-fold (p = 0.04), with a restored gene expression of LGR5 (~4.11-fold change, p = 0.0004), as well as an increased expression of Ly6a (~3.51-fold change, p = 0.005) and CLU (~2.5-fold change, p = 0.01), markers of revival stem cells. In conclusion, Ech A is harmless to intestinal tissues; rather, it promotes the maintenance and regeneration of the intestinal epithelium, suggesting possible beneficial effects on the intestine when used as an oral medication. 相似文献