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Garcia-Vazquez E Perez J Martinez JL Pardiñas AF Lopez B Karaiskou N Casa MF Machado-Schiaffino G Triantafyllidis A 《Journal of agricultural and food chemistry》2011,59(2):475-480
DNA analysis of hake products commercialized in southern European (Spanish and Greek) market chains have demonstrated more than 30% mislabeling, on the basis of species substitution. Tails and fillets were more mislabeled than other products, such as slices and whole pieces. African species were substitute species for products labeled as American and European species, and we suggest it is a case of deliberate economically profitable mislabeling because real market prices of European and American hake products are higher than those of African in Spanish market chains. The presented results suggest fraud detection that disadvantages African producers. Government-mandated genetic surveys of commercial hakes and the use of subsequent statements of fair trade on labels of seafood products could help to reduce fraud levels in a global market of increasingly conscious consumers sensitive to ethical issues. 相似文献
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Ana Jesus Fernando Dures Nikoletta Szemerdi Joana Freitas-Silva Paulo Martins da Costa Eugnia Pinto Madalena Pinto Gabriella Spengler Emília Sousa Honorina Cidade 《Marine drugs》2022,20(5)
The growing number of infectious diseases around the world threatens the effective response of antibiotics, contributing to the increase in antibiotic resistance seen as a global health problem. Currently, one of the main challenges in antimicrobial drug discovery is the search for new compounds that not only exhibit antimicrobial activity, but can also potentiate the antimicrobial activity and revert antibiotics’ resistance, through the interference with several mechanisms, including the inhibition of efflux pumps (EPs) and biofilm formation. Inspired by macroalgae brominated bromophenol BDDE with antimicrobial activity, a series of 18 chalcone derivatives, including seven chalcones (9–15), six dihydrochalcones (16–18, and 22–24) and five diarylpropanes (19–21, and 25 and 26), was prepared and evaluated for its antimicrobial activity and potential to fight antibiotic resistance. Among them, chalcones 13 and 14 showed promising antifungal activity against the dermatophyte clinical strain of Trichophyton rubrum, and all compounds reversed the resistance to vancomycin in Enterococcus faecalis B3/101, with 9, 14, and 24 able to cause a four-fold decrease in the MIC of vancomycin against this strain. Compounds 17–24 displayed inhibition of EPs and the formation of biofilm by S. aureus 272123, suggesting that these compounds are inhibiting the EPs responsible for the extrusion of molecules involved in biofilm-related mechanisms. Interestingly, compounds 17–24 did not show cytotoxicity in mouse embryonic fibroblast cell lines (NIH/3T3). Overall, the results obtained suggest the potential of dihydrochalcones 16–18 and 22–24, and diarylpropanes 19–21, 25 and 26, as hits for bacterial EPs inhibition, as they are effective in the inhibition of EPs, but present other features that are important in this matter, such as the lack of antibacterial activity and cytotoxicity. 相似文献
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Essential oils (EOs) from Rosemary, Rosmarinus officinalis (Lamiaceae), Orange, Citrus sinensis (Rutaceae), Lavandula, Lavandula angustifolia (Lamiaceae), False Yellowhead, Dittrichia viscosa (Asteraceae) and their major components were evaluated against root knot nematode, Meloidogyne incognita and Meloidogynejavanica. Second stage juveniles' (J2) paralysis and egg hatch inhibition were studied, while pulverized plant parts were tested for nematodes biological cycle arrest. All EOs paralyzed J2 and M. incognita were found more sensitive than M javanica with the EC50/4 days calculated at 250, 3,650 and 4,260 12g/mL for 1). viscosa, L. angustifolia and R. officinalis, respectively. Similarly, all EOs inhibited nematodes egg hatch and D. viscosa exhibited the highest inhibition on egg hatch (100% inhibition at 5 μg/mL). A significant influence of constituent terpenes (limonene, 1,8-cineole, linalool, camphor, L-borneol, caryophyllene oxide, β-eudesmol) dose and exposure time was indicated on egg hatch inhibition (56% to 100% at 500 μg/mL and 1,000 μg/mL), while only β-eudesmol achieved paralysis of J2 and specifically against M. incognita (EC50/1d = 50μg/mL). Interestingly, the most active botanical species arresting Meloidogyne spp. biological cycle in soil was C. sinensis (EC50 = 2 mg/g) and the most sensitive nematode species was M. javanica. The larvicidal and egg hatch inhibition activity holds promise towards the optimization of artificial terpene mixtures as novel and effective natural nematicides. Complex interactions of primary compounds and subsequent decomposition derivates compose efficacy profile of soil amendments. 相似文献