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51.
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Andres KM Kent M Siedlecki CT Mayer J Brandão J Hawkins MG Morrisey JK Quesenberry K Valli VE Bennett RA 《Veterinary and comparative oncology》2012,10(2):82-94
An overall median survival time (MST) and prognostic factors in rabbits with thymomas treated with megavoltage radiation therapy (RT) were determined in this multi-institutional retrospective case analysis. Medical records for 19 rabbits with suspected or confirmed thymomas treated with RT were evaluated for data including signalment, haematological and serum biochemistry abnormalities, presence of pleural effusion, radiation plan, body weight, total radiation dose and institution administering RT. Statistical significance of these factors related to overall survival was assessed. An overall MST for all 19 rabbits was 313 days; exclusion of 3 rabbits that died acutely during the first 14 days of RT yielded a MST of 727 days. The only factor associated with a significantly decreased survival time was having a body weight lower than mean body weight of 1.57 kg. Radiation treatment-associated complications were infrequent and included radiation-induced myocardial failure, radiation pneumonitis and alopecia. 相似文献
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Yanchong Huangfu Michael E. Essington Shawn A. Hawkins Forbes R. Walker John S. Schwartz Alice C. Layton 《Communications in Soil Science and Plant Analysis》2019,50(11):1358-1369
Determining the total elemental concentrations of soils requires a total dissolution method, in which hydrofluoric acid (HF) is commonly used. However, this method is tedious and risky due to the dangerous reagent HF. This study compared a single acid extraction technique using a nitric acid (HNO3) extraction method to total dissolution (HF + microwave assisted aqua regia) for evaluating the total elemental concentrations in soils and sediments. The two methods were used to analyze the elemental content of soils and sediments from the Oostanaula Creek and Pond Creek watersheds in East Tennessee. Twenty-one elements (Al, Ba, Ca, Co, Cr, Cu, Fe, K, La, Li, Mg, Mn, Nd, P, S, Si, Sr, Ti, V, Zn, and Zr) were subsequently measured using inductively coupled plasma optical emission spectrometry (ICP-OES). The extraction efficiency for HNO3 relative to the total was compared and discussed. In general, HNO3 can extract the elements in absorbed phases and those residing in non-silicate minerals. Six elements (Ba, Co, Fe, Ca, Mn, and P) generated significant correlations between total and HNO3 in both OC and PC watersheds. Finally, the elements were grouped according to the interrelationships of their total elemental concentrations based on the dendrogram plots, suggesting their geochemical association in soils and sediment forming minerals. 相似文献
55.
Earthworm populations in septic system filter fields and potential effects on wastewater renovation 总被引:1,自引:0,他引:1
Carrie L. Hawkins Martin J. Shipitalo E. Moye Rutledge Mary C. Savin Kristofor R. Brye 《Applied soil ecology》2008,40(1):195-200
Wastewater renovation in septic-system filter fields can be affected by preferential flow through soil macropores. Anecic earthworm species make deep vertical burrows that may reduce renovation by acting as preferential flow paths that decrease effluent contact with the soil matrix. On the other hand, endogeic earthworms make largely horizontal burrows that may enhance wastewater renovation by distributing the effluent over a larger area. Additionally, the moist, nutrient-rich environment in filter fields may increase earthworm populations by enhancing their survival. Therefore, our objectives were to determine earthworm numbers and biomass with distance from soil treatment trenches, and identify species present to estimate potential effects on wastewater renovation. Five septic systems were investigated. At each site, earthworm populations were measured using formalin extraction at 10 locations along each of three 7-m long transects perpendicular to the trenches. There were an average of 6.4 times more earthworms and 5.4 times more earthworm biomass within 1 m of the trench than in the background (3.5–7.0 m from the trenches) in 13 of the 15 transects. This suggests that earthworms may have a significant effect on the movement of effluent. Because only epigeic and endogeic species were observed, the potential for reduced renovation and groundwater contamination at these sites is likely low. This may not be the case in areas with large numbers of anecic earthworms. 相似文献
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Pratt SM Christian JA Paige Jackson L Hawkins JF Sojka JE 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2008,37(2):253-255
A 16-year-old castrated male Arabian horse was presented to the Purdue University Veterinary Teaching Hospital with a 4-hour history of colic. Initial examinations provided strong evidence for small intestinal obstruction. Abdominal surgery revealed a strangulating lipoma, and 25 feet of small intestine were resected. Postoperatively, the horse developed obstructive ileus due to adhesion formation, which required a second laparotomy. During and after surgery, the abdomen was lavaged with sodium carboxymethylcellulose (CMC). One week after the second surgery, evaluation of peritoneal fluid revealed an inflammatory exudate, with many macrophages containing amorphous to granular, pink to magenta phagocytosed material. Extracellular aggregates of the material were also observed. The material was consistent with CMC. To our knowledge, this report is the first to demonstrate the phagocytosis of CMC by peritoneal fluid macrophages. 相似文献
58.
Molly D. Gleeson Bret A. Moore Sydney G. Edwards Sarah Stevens April L. Childress James F.X. Wellehan Jessica Robertson Christopher J. Murphy Michelle G. Hawkins Joanne Paul‐Murphy 《Veterinary ophthalmology》2019,22(1):67-75
An adult great‐horned owl (Bubo virginianus; GHOW) presented with a history of recurrent corneal ulceration of the right eye (OD). Findings included ulcerative superficial keratitis, proliferative conjunctivitis, and iris pigmentary changes. The ulcer was initially nonresponsive to medical therapy, but showed rapid and appropriate healing following diamond burr debridement. Proliferative conjunctivitis markedly improved following topical antiviral therapy with cidofovir 1%, interferon alpha 2B ophthalmic solutions, and oral l ‐lysine. Histopathologic evaluation of a conjunctival biopsy revealed epithelial features suspicious for viral cytopathic changes and intranuclear structures suspicious for viral inclusions, suggestive of a possible viral‐induced papillomatous conjunctivitis. A novel alphaherpesvirus, referred to as Strigid Herpesvirus 1 (StrHV1), was identified using PCR and gene sequencing. This case represents a new clinical manifestation of a previously unreported herpesvirus in the GHOW. Identification of the herpes virus was critical to administration of appropriate therapy and resolution of the conjunctivitis, and corneal epithelial debridement promoted resolution of the chronic corneal epithelial defect. 相似文献
59.
Heidi-Jayne Hawkins Hans Hettasch Jolanta Mesjasz-Przybylowicz Wojciech Przybylowicz Michael D. Cramer 《Scientia Horticulturae》2008,117(4):357-365
South African Proteaceae are adapted to the low soil phosphorus (P) concentrations of the Cape Floristic Region. The efficient P uptake by Proteaceae means that these plants experience phosphorus (P) toxicity at lower rhizosphere [P] than crop plants. This is only problematic when cultivating Proteaceae (and many plants from this region) on previously agricultural land with high residual soil [P]. In this study we hypothesize that P toxicity will result in element imbalances in leaves of Proteaceae and information from this study aims to facilitate ameliorative treatments. Phosphorus toxicity was induced on-farm in Leucadendron ‘Safari Sunset’ (Proteaceae) with subsequent mapping of element distribution in non-necrotic leaf tissue using micro particle-induced X-ray emission spectrometry. Phosphate supply up to 0.01 mM in a fertigation solution resulted in increased stem length of Leucadendron ‘Safari Sunset’ while P concentrations in excess of this resulted in decreased stem length, increased leaf [P] up to 0.25% (w/w) and, between 1 mM and 5 mM P supply, typical P toxicity symptoms were observed. High P supply (5 mM P) resulted in increased leaf [P] in most leaf tissues including the epidermis, where calculations from an equilibrium speciation model indicated that there was 30% more dissolved PO43− in the epidermis compared to leaves at low P supply (0 mM added P on soil with 34 mg P kg−1). Concomitantly, bundle sheath and epidermal [Ca] were reduced and 10% more Ca was predicted to be adsorbed and precipitated as hydrapatite at high P supply. High P supply resulted in increased leaf [Cl] and [Mn] in all tissues studied; decreased total leaf [Fe], bundle sheath, xylem, phloem and epidermal [Fe] and decreased total leaf [Zn] and xylem and phloem [Zn]. The observed symptoms of P toxicity in Leucadendron ‘Safari Sunset’ (necrosis in some plants, chlorosis and leaf rosetting) co-occurred with (1) excess PO43−, which may bind Ca in the epidermis (leading eventually to necrosis); (2) reduced [Fe] and increased [Mn] (leading to chlorosis) and (3) reduced total and vascular [Zn] (leading to leaf rosetting). 相似文献
60.
Hawkins SS Griffiths LJ Dezateux C Law C;Millennium Cohort Study Child Health Group 《Public health nutrition》2007,10(9):891-896
OBJECTIVE: To examine the relationship of maternal employment characteristics, day care arrangements and the type of maternity leave pay to breast-feeding for at least 4 months. DESIGN: Cohort study. SETTING: Babies aged 9 months in the Millennium Cohort Study, born between September 2000 and January 2002. SUBJECTS: A total of 6917 British/Irish white employed mothers with singleton babies. RESULTS: Mothers employed part-time or self-employed were more likely to breast-feed for at least 4 months than those employed full-time (adjusted rate ratio (aRR) and 95% confidence interval (CI) 1.30 (1.17-1.44) and 1.74 (1.46-2.07), respectively). The longer a mother delayed her return to work postpartum, the more likely she was to breast-feed for at least 4 months (P for trend < 0.001). Mothers were less likely to breast-feed for at least 4 months if they returned to work for financial reasons (aRR 0.86, 95% CI 0.80-0.93) or used informal day care arrangements rather than care by themselves or their partner (aRR 0.81, 95% CI 0.71-0.91). Mothers were more likely to breastfeed for at least 4 months if their employer offered family-friendly (aRR 1.14, 95% CI 1.02-1.27) or flexible work arrangements (aRR 1.24, 95% CI 1.00-1.55), or they received Statutory Maternity Pay (SMP) plus additional pay during their maternity leave rather than SMP alone (aRR 1.13, 95% CI 1.02-1.26). These findings were independent of confounding factors, such as socio-economic status and maternal education. CONCLUSIONS: Current policies may encourage mothers to enter or return to employment postpartum, but this may result in widening inequalities in breast-feeding and persistence of low rates. Policies should aim to increase financial support and incentives for employers to offer supportive work arrangements. 相似文献