1. One hundred and seven laying hens were hypophysec‐tomised to clarify the relationship between hypophysectomy and the effect of progesterone (P4) on ovulation.
2. Hens were hypophysectomised at 6 intervals from 4.5 to 11.0 h before the expected time of ovulation. Ovulation occurred in the hens operated on from 4.5 to 7.3 h, but did not take place in birds operated on from 9.2 to 9.8 h before the expected time of ovulation.
3. When a single dose of P4 (2 mg/hen) was injected iv immediately after the removal of the anterior pituitary from 7.5 to 9.8 h before the expected time of ovulation, ovulation was induced. However, the percentage of hens responding decreased in proportion to the lapse of time between the hypophysectomy and the expected time of ovulation. No ovulation was induced in hens which were hypophysectomized and given P4 10.2 to 11.0 h before the expected time of ovulation.
4. It is suggested that ovulation is induced by P4 alone possibly in the absence of preovulatory gonadotrophins and that P4 acts directly on the ovary to induce follicle rupture. 相似文献
SUMMARY: Ambiguous paternity can be incorporated into the mixed model equations (MME) by including the average numerator relatinship matrix (average A), which averages the true sire-offspring relationship over the putative sires. A previous study has shown that some overestimation of genetic trend results from this substitution. A population of 40 breeding females and 2 breeding males was simulated 1,000 times with either random mating or sequential selection continuing for 8 breeding cycles. In the selection case candidates were ranked on estimated breeding values (EBVs) calculated from the MME with an animal model and the average A. Variances of the EBVs and prediction errors were computed. The results showed the average A incorrectly perceives both the variance of family sizes among males and the variance loss due to selection to be smaller. This will lead to an overestimation of genetic trend. ZUSAMMENFASSUNG: Folgerungen aus der Anwendung einer durchschnittlichen Verwandtschaftsmatrix bei der Zuchtwertsch?tzung für eine Population mit mehreren V?tern in einer Paarungsgruppe In den Mischmodellgleichungen kann eine unklare v?terliche Abstammung durch die Verwendung einer durchschnittlichen Verwandtschaftsmatrix, die die Abstammung zu gleichen Teilen über die m?glichen V?ter aufteilt, berücksichtigt werden. Eine frühere Arbeit hat gezeigt, da? diese Ma?nahme zu einer gewissen übersch?tzung des genetischen Fortschritts führt. Eine Population mit 40 weiblichen und 2 m?nnlichen Tieren wurde 1000mal über 8 Paarungsperioden simuliert und zwar mit und ohne gerichteter Selektion. Im Falle der Selektion wurden die Tiere aufgrund der mit einem Tiermodell und der durchschnittlichen Verwandtschaftsmatrix gesch?tzten Zuchtwerte geordnet. Die Varianzen der Zuchtwerte und der Sch?tzfehler wurden berechnet. Die Ergebnisse zeigen, da? durch eine durch-schnittliche Verwandtschaftsmatrix die Varianz der Gr??e der Nachkommensgruppen der V?ter und der Verlust an genetischer Varianz aufgrund der Selektion untersch?tzt wird. Dies führt zu einer übersch?tzung des genetischen Fortschritts. 相似文献
Polioencephalomalacia (PEM), hereafter used to refer to the specific lesion of cerebrocortical necrosis, developed in 11 of 110 mature cattle on pasture in central Saskatchewan. The primary water source contained a markedly elevated level of sodium sulfate (7200 ppm). The significant clinical findings of the herd investigation included depression, ataxia, cortical blindness, dysphagia, and death. Diagnosis of PEM was confirmed by histopathological evidence of cerebrocortical and subcortical necrosis with microvascular fibrinoid necrosis predominantly in the thalamic region of three affected cattle. The histopathology of sulfate-associated PEM observed in this herd appears to be unique and its features are presented and discussed. Mean levels for serum transketolase, copper, red blood cell transketolase activity, and thiamine (vitamin B1) in all exposed young (n = 100) and mature (n = 99) animals did not reveal evidence of deficiencies. Although the blood thiamine status of the seven surviving, affected animals was not evaluated before treatment with exogenous thiamine, 199 members of the herd had blood thiamine levels within the reference range at the time of the outbreak. The outbreak resolved after cattle were moved to a water source containing acceptable levels of sodium sulfate. 相似文献
The effects of offspring sex, weight, age, and level of interaction with the dam on responses to weaning were examined to assist in the development of a weaning protocol for alpacas. In the first study, preand post-weaning activities, and weight change over Days -12-0,0-7 and 7-16 with respect to weaning, were recorded for 20 dam-offspring (hembra-cria) pairs aged 81-200 days. Pre-weaning changes in dam and offspring weights were positively related (P<0.05). Although heavier crias tended to be found closer to their dams than lighter crias (P<0.05) no additional effect of age on the dam-offspring relationship was found. Following weaning, cria growth rates were low over Days 0-7 but improved over Days 7-16, and hembra weight change followed the same pattern. Over Days 0-2, grazing and sitting activities of hembras and crias were replaced by standing and walking along paddock fencelines, although by Day 2 fenceline activities had decreased (P<0.05). Crias which were more frequently observed at fencelines had lower post-weaning growth rates (P<0.05). In the second study, pre-weaning sucking behaviour, and weight change over Days -30-0, 0-8 and 8-16 with respect to weaning, were recorded for 19 hembra-cria pairs aged 124-160 days. During 10 hours of observation on Days -5 and -4, the total duration of sucking by individual crias varied from 0-18 minutes, and the mean +/- SEM duration of sucking was 1.94 +/- 0.113 minutes. Cria sucking behaviour was positively related to growth rate prior to and weight at weaning (P<0.05). As in the first study, pre-weaning changes in dam and offspring weights were positively related (P<0.05). Following weaning, growth rates of the crias were depressed and the hembras lost weight over Days 0-8 and 8-16. The changes in growth rate and behaviour in Studies 1 and 2 indicated that weaning can be stressful for hembras and crias. However, there was no evidence from either study that pre-weaning behavioural or physical characteristics were related to the changes. 相似文献