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In this two year study we investigated the effect that the level of concentrate in feedlot diet had on the occurrence of health problems in bull calves belonging to two multibreed groups.

In each of the two years, the 168 day feedlot period was divided into two equal periods of 77 days with an intervening 14 day adjustment period. During the first period, the animals in half of the pens within each breed-group received a high concentrate (85% grain) diet (H) while the rest of the pens received a diet (L) of hay ad libitum and half as much concentrate as the bulls on high concentrate. The L diet contained an average of 48% grain. In the second period, diets of bulls in half of the pens within each breed-group were switched from L to H and vice versa. During the feedlot period, the incidence of sickness among bulls was recorded. Disease incidence was higher in the second year compared to the first. In the second year, 49 out of 56 (87.5%) calves on the high concentrate diet required treatment for respiratory infections compared to only four (7.14%) in bulls on the low concentrate diet. The results suggest that a high concentrate diet for animals in feedlots may be more stressful to calves coming directly to the feedlot following weaning compared to a low concentrate diet, thereby acting as an additional predisposing factor to respiratory infections.

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We examined 18 horses with clinical signs of chronic obstructive pulmonary disease (COPD) using physical examination, cytological and bacteriological evaluation of bronchoalveolar fluid, and percutaneous lung biopsy. In 16 cases, histological examination of lung tissue confirmed the diagnosis of COPD. Two horses were excluded: one had uncomplicated bacterial pneumonia and in the other a satisfactory lung biopsy could not be obtained. In horses with COPD, the most common historical complaint was coughing, which was reported in 88%. The most frequently detected abnormal finding on physical examination was abnormal lung sounds; these were detected in 69% of horses at rest and in 88% of horses breathing deeply into a bag. A novel finding was that 29% of horses had lung sounds that were quieter than would be expected for the degree of respiratory effort. Horses with COPD had increased percentages of neutrophils and decreased percentages of lymphocytes and macrophages in their bronchoalveolar lavage fluid. Bronchiolar neutrophil infiltration and peribronchiolar mast cell accumulation in lung biopsy tissue had the highest correlation with clinical condition. The severity of pathological changes in biopsies of lung did not predict whether the horse would die in the two to four year follow-up period. Horses that died in the follow-up period were more severely affected clinically at initial presentation than horses that were alive at the end of the follow-up period.  相似文献   
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Magnetic resonance imaging (MRI) data were correlated with clinical and cerebrospinal fluid (CSF) findings in one cat and two dogs with brain lesions. In all three cases, localization of the lesions, as determined clinically, was confirmed using MRI. Magnetic resonance imaging also helped us to define the full extent of the lesion(s) in each case. In one case, the lesion would have been diagnosed as purely inflammatory based on the abnormalities in the CSF. The MRI study, however, showed a homogeneous mass with circumferential changes characteristic of peritumoral edema or inflammation. In two cases, the MRI findings were confirmed at necropsy. An MRI study was also done on a normal dog, demonstrating the variable contrast and anatomical detail possible using this technique. We also discuss difficulties in identifying tumor type using MRI.  相似文献   
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