Agricultural policies and the capitalist State

The paper examines the social contradictions generated by patterns of reproduction of accumulation of capital, social legitimation and by present agricultural policies fostered by the State. Through a scrutiny of the role of the State in capitalism it is argued that agricultural overproduction, the widening of the gap between small and large farms, the fiscal crisis of the State associated with agricultural programs and waste of resources are the outcomes of an attempt on the part of the State to promote simultaneously accumulation and legitimation. The possibility of enhancing accumulation and maintaining legitimation clashes with the diverse socio-economic demands associated with the present agricultural production system and the general viability of the social structure as a whole.     

Evolutionary formation of new centromeres in macaque

A systematic fluorescence in situ hybridization comparison of macaque and human synteny organization disclosed five additional macaque evolutionary new centromeres (ENCs) for a total of nine ENCs. To understand the dynamics of ENC formation and progression, we compared the ENC of macaque chromosome 4 with the human orthologous region, at 6q24.3, that conserves the ancestral genomic organization. A 250-kilobase segment was extensively duplicated around the macaque centromere. These duplications were strictly intrachromosomal. Our results suggest that novel centromeres may trigger only local duplication activity and that the absence of genes in the seeding region may have been important in ENC maintenance and progression.     

Global contested terrain: The case of the tuna-dolphin controversy

Employing the case of the global tuna-fish industry, it is argued that the process of globalization is contested terrain as it opens free spaces to some classes or groups and closes free spaces to others; that the nation-States' regulatory abilities are weakened; and finally, that while some social movements may gain, others are marginalized. Three basic conclusions are reached. (1) The industry's actions were successfully contested by environmental groups supported by the legislative and judicial branches of the US State. (2) Simultaneously, pro-environmental legislation is currently threatened, along with several national and international environmental accords. (3) Workers in the US and, particularly, in Latin America are paying the consequences of the introduction of pro-environmental legislation and the actions of transnational corporations (TNCs).Douglas H. Constance is Research Associate of Rural Sociology at the University of Missouri-Columbia. His research interests include the sociology of agriculture and environmental sociology. He is the author of several journal articles and is coauthor with Alessandro Bonanno of the forthcoming bookCaught in the Net: The Global Tuna Industry, Environmentalists, and the State.     

Erylusamides: Novel Atypical Glycolipids from Erylus cf. deficiens

Among marine organisms, sponges are the richest sources of pharmacologically-active compounds. Stemming from a previous lead discovery program that gathered a comprehensive library of organic extracts of marine sponges from the off-shore region of Portugal, crude extracts of Erylus cf. deficiens collected in the Gorringe Bank (Atlantic Ocean) were tested in the innovative high throughput screening (HTS) assay for inhibitors of indoleamine 2,3-dioxygenase (IDO) and showed activity. Bioassay guided fractionation of the dichloromethane extract led to the isolation of four new glycolipids, named erylusamide A–D. The structures of the isolated compounds were established by 1D and 2D nuclear magnetic resonance (NMR) spectroscopy, high-resolution electrospray ionization mass spectrometry (HR-ESI-MS) and chemical derivatization. The metabolites shared a pentasaccharide moiety constituted by unusual highly acetylated d-glucose moieties as well as d-xylose and d-galactose. The aglycones were unprecedented long chain dihydroxyketo amides. Erylusamides A, B and D differ in the length of the hydrocarbon chain, while erylusamide C is a structural isomer of erylusamide B.     

Plication of the free wall of the left ventricle in dogs with doxorubicin-induced cardiomyopathy

OBJECTIVE: To evaluate plication of the free wall of the left ventricle, which reduces the left ventricular area and volume, as a method to improve the left ventricular systolic function without cardiopulmonary bypass. ANIMALS: 8 mixed-breed adult dogs. PROCEDURE: Dilated cardiomyopathy (DCM) was induced in each dog by administration of doxorubicin (30 mg/m2, i.v., q 21 d for 168 days).Two dogs died during induction of cardiomyopathy. Plication surgery was performed in 4 dogs. Two dogs did not ondergo to surgery (control group). Values for cardiac output (CO), 2-dimensional and M-mode echocardiography, arterial blood pressure, electrocardiography, blood cell counts, and serum biochemical analyses were recorded after induction of DCM (baseline) and 1, 2, 7, 15, 21, 30, 60, 90, 120, 150, and 180 days after plication surgery. Ambulatory ECG (Holter) recordings were conducted for 24 hours on the day of surgery. RESULTS: 1 dog died after plication surgery. The remaining dogs undergoing ventricular plication had a significant improvement in CO, ejection fraction, and fractional shortening and reductions of left ventricular area and volume after surgery. Electrocardiographic and Holter recordings revealed premature ventricular complexes, which resolved without treatment during the first week after surgery. Clinical condition of the control dogs declined, and these 2 dogs died approximately 40 days after induction of cardiomyopathy. CONCLUSIONS AND CLINICAL RELEVANCE: Plication of the free wall of the left ventricle improved left ventricular systolic function in dogs with doxorubicin-induced cardiomyopathy. Additional studies are needed to evaluate its application in dogs with naturally developing DCM.     

Is the establishment of MPAs enough to preserve endangered intertidal species? The case of Patella ferruginea in Mal di Ventre Island (W Sardinia,Italy)

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Assessing the potential of marine Natura 2000 sites to produce ecosystem‐wide effects in rocky reefs: A case study from Sardinia Island (Italy)

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Cross-sectional study of Brucella spp. using real-time PCR from bovine whole blood in Colombia

Veterinary Research Communications - A cross-sectional study was conducted in Colombia to recover Brucella spp. DNA from bovine whole-blood samples through probe-based real-time PCR (qPCR). By an...