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51.
Keisuke SUGIMOTO Yoko FUJII Hiroshi SUNAHARA Takuma AOKI 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(9):1101-1108
Hypertrophic cardiomyopathy (HCM) in cats is characterized by concentric left
ventricular (LV) hypertrophy and both diastolic and systolic dysfunction. Although
impaired cardiac function detected by tissue Doppler imaging (TDI) in cats with HCM was
previously reported, reference ranges of TDI in normal cats and cats with HCM have been
reported as widely variable. Two-dimensional speckle tracking echocardiography (STE) was
useful for assessment of cardiac function in human patients with HCM, but clinical utility
was not known in cats. The aim of this study was to assess global and segmental LV
myocardial function using STE in cats with HCM whose TDI variables were within the
reference range. A total of 35 cats of different breeds were enrolled in this study. The
HCM group (n=22) was cats diagnosed as HCM without left atrial enlargement and with normal
TDI measurements. HCM cats were further divided into a segmental hypertrophy (S-HCM) group
and a diffuse hypertrophy (D-HCM) group. The control group consisted of 13 clinically
healthy cats. No cats in any group showed any clinical symptoms. Conventional
echocardiography, TDI, and global and segmental STE indices were evaluated and compared
between groups. Only the longitudinal strain rate during early diastole was significantly
decreased in both HCM groups, even in all segments including those without hypertrophy in
S-HCM group. This study suggests that STE parameters are the more sensitive variables
compared with conventional TDI parameters to detect early myocardial diastolic dysfunction
in cats with HCM. 相似文献
52.
Hiroshi SUNAHARA Yoko FUJII Keisuke SUGIMOTO Takuma AOKI Gou SUGAHARA Kinji SHIROTA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(1):95-99
A two-month-old female Chihuahua was diagnosed as severe pulmonary valvular
stenosis (PS). Although balloon valvuloplasty (BV) was successfully performed, restenosis
was observed 19 months after the procedure. Euthanasia was chosen due to low output
syndrome during the surgical repair attempted when the dog was 5 years old. Postmortem
examination revealed markedly thickened pulmonary valve due to the increase of
extracellular matrix which might be produced by increased α smooth muscle actin-positive
myofibroblasts. The thickening of the valve was associated with restriction of the valve’s
motion, resulting in restenosis in the present case. This is the first case report
documented histopathological and immunohistochemical findings of the restenotic pulmonary
valve in dogs with PS after BV. 相似文献
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54.
Naomi MIKAWA Tomoko UTOH Noriyuki HORIE Akihiro OKAMURA Yoshiaki YAMADA Atsushi AKAZAWA Satoru TANAKA Katsumi TSUKAMOTO Ikuo HIRONO Takashi AOKI 《Fisheries Science》2004,70(6):960-970
ABSTRACT: Estrogen receptor (ER) cDNA was cloned from the liver of common Japanese conger Conger myriaster . Common Japanese conger ER cDNA contains 2543 nucleotides including an open reading frame that encodes 596 amino acids, with a molecular weight of 66.1 kDa. The deduced amino-acid sequence of the common Japanese conger ER shares 85% identity with that of eel Anguilla japonica ER-β, and 39–46% and 53–59% identity with the deduced sequences of ER-α and ER-β of other species, respectively. In a phylogenetic analysis, the common Japanese conger ER was found to cluster with the ER-β of other species. The common Japanese conger ER-β also has six domains (A–F), which are conserved in the nuclear receptor superfamily. The amino-acid sequences in the C and E domains were highly conserved between common Japanese conger ER-β and other ER. However, the other domains showed low homology. In the female common Japanese conger, ER-β mRNA was highly expressed in the liver and pituitary gland. The expression levels of the ER-β gene increased from the oil droplet stage to the primary yolk globule stage and were maintained until the migratory nucleus stage. 相似文献
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56.
The coding region sequence of the Oryza sh4 gene homologue in Echinochloa was analyzed in relation to the shattering nature of spikelets and the phylogeny of homologue copies in the Asian annual polyploidy Echinochloa . The Sh4 homoeologue copies were detected in Echinochloa oryzicola , Echinochloa crus-galli , Echinochloa stagnina, Echinochloa colona , and Echinochloa crus-pavonis . Amino acid sequence differences did not lead to a functional change in the sh4 gene between the shattering and non-shattering types in E. crus-galli , E. oryzicola , and E. colona . A phylogenetic analysis of the homoeologous copy sequences indicated a genomic relationship between the Asian Echinochloa species and supported that the allohexaploid E. crus-galli shares two genomes with its parental donor, E. oryzicola . The Asian perennial tetraploid species, E. stagnina , shares one genome with E. oryzicola and possesses an unknown genome. Echinochloa crus-pavonis , from the New World, shows a close affinity of two genomes with E. crus-galli and E. oryzicola . Echinochloa colona showed distant affinities in all homoeologous copies. 相似文献
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58.
Cloning of kuruma prawn Marsupenaeus japonicus crustin-like peptide cDNA and analysis of its expression 总被引:1,自引:0,他引:1
Achara RATTANACHAI Ikuo HIRONO Tsuyoshi OHIRA Yukinori TAKAHASHI Takashi AOKI 《Fisheries Science》2004,70(5):765-771
ABSTRACT: Antimicrobial peptides serve as an important component of the innate immune system of all species by functioning to provide a rapid first line defense against infection. Arthropod antimicrobial peptides have been well described in insects, whereas only a few molecules have been identified in crustaceans. Five variants (types 1–5) of Marsupenaeus japonicus crustin-like peptide cDNA that were obtained from a hemocyte cDNA library and polymerase chain reaction (PCR) amplification are reported here. Marsupenaeus japonicus crustin-like peptide type 1, the predominant type, has a cDNA consisting of 679 nucleotides and an open reading frame consisting of 573 base pairs coding for 191 amino acid residues. Other types contain varying glycine-rich repeats at the N-terminal amino acid sequences. The deduced amino acid sequences of these variants are highly similar to those of Litopenaeus setiferus (80% identity), Litopenaeus vannamei (80% identity) and Carcinus maenas crustins (44% identity). Expression of Marsupenaeus japonicus crustin-like peptide mRNA was detected in hemocytes, but not in the heart, hepatopancreas, gill, fore-gut, mid-gut, muscle, subcuticular epithelium or ovary. The expression level of crustin-like peptide mRNA increased significantly 1, 3 and 7 days post-peptidoglycan feeding as determined by quantitative real-time PCR. These results suggest that crustin-like peptide could have an important role in shrimp defense mechanisms. 相似文献
59.
SHAN YUNFENG IZUTA TAKESHI AOKI MASATOSHI TOTSUKA TSUMUGU 《Water, air, and soil pollution》1997,97(3-4):355-366
Water, Air, &; Soil Pollution - One-year-old seedlings of red pine (Pinus densiflora Sieb. and Zucc.) were grown in typic red-yellow forest soil (Typic Hapludults) artificially adjusted to pH... 相似文献