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41.
Martina Mosing Dr med vet DECVAA Isabelle K. Iff Dr med vet DECVAA Wolfgang Nemetz MD 《Journal of Veterinary Emergency and Critical Care》2008,18(5):532-536
Objective – To describe general anesthesia and successful resuscitation of a dog developing asystole and apnea during extradural injection of local anesthetic and an opioid. Case Summary – A Beagle with a ruptured cranial cruciate was premedicated with acepromazine and methadone. Anesthesia was induced with propofol and, after endotracheal intubation, maintained using isoflurane in oxygen. During extradural injection of a mixture of lidocaine, bupivacaine, and morphine the dog developed apnea and asystole. Cardiopulmonary cerebral resuscitation was started promptly and the dog was successfully resuscitated. New Information Provided – Asystole and apnea are possible serious side effects of extradural anesthesia in dogs. With adequate monitoring and early detection successful resuscitation is possible. 相似文献
42.
OBJECTIVE: To investigate the onset and duration of neuromuscular blockade of rocuronium bromide and its associated haemodynamic effects at three doses in healthy horses. STUDY DESIGN: Prospective, randomized experimental study. ANIMALS: Seven adult horses aged 3-20 (mean 10.3) years and weighing 466 +/- 44 (mean +/- SD) kg. METHODS: Horses were anaesthetized three times with at least 2 weeks between. They were pre-medicated with 0.6 mg kg(-1) xylazine and 0.01 mg kg(-1) butorphanol i.v.. Anaesthesia was induced with 2.2 mg kg(-1) ketamine and 0.1 mg kg(-1) diazepam i.v.. Following orotracheal intubation anaesthesia was maintained with isoflurane in 100% oxygen. Intermittent positive pressure ventilation was initiated and the horses were ventilated at a respiratory rate (fr) of 4-8 breaths minute(-1). Neuromuscular function was monitored with an acceleromyograph. The peroneal nerve was stimulated with train-of-four (TOF) mode at 2 Hz every 15 seconds. Each horse received, in randomly assigned order, one of the three doses of rocuronium: 0.2 mg kg(-1) (D02), 0.4 mg kg(-1) (D04) or 0.6 mg kg(-1) (D06) i.v.. Lag time, onset time, time of no response, duration of action and the TOF ratio 0.7 and 0.9 were measured. Recovery time (T1(25-75)) was calculated. Vital parameters were recorded at 5-minute intervals on a standard anaesthetic record form. RESULTS: Rocuronium produced a dose-dependent duration of action in isoflurane-anaesthetized horses. 100% block was observed in D04 and D06 but not in D02, in which the maximum decrease of the first twitch of TOF attained was 91.5 +/- 16.5%. Time to T1(25) was 13.1 +/- 5.5 minutes, 38.6 +/- 10.1 minutes and 55 +/- 9.8 minutes in D02, D04 and D06 respectively. There was a significantly shorter time for TOFR 0.9 with 0.2 mg kg(-1) compared with 0.4 and 0.6 mg kg(-1) rocuronium. T1(25-75) in D04 and D6 was not statistically significantly different. Heart rate, systolic, diastolic and mean arterial blood pressure increased slightly during the observation period. CONCLUSION: Rocuronium is an effective nondepolarizing muscle relaxant in horses under isoflurane anaesthesia. It had a dose-dependent onset and duration of action. Rocuronium did not produce significant changes in the measured cardiovascular parameters. 相似文献
43.
Marzia Bo Martina Coppari Federico Betti Francesco Enrichetti Marco Bertolino Francesco Massa Simone Bava Guido Gay Riccardo Cattaneo-Vietti Giorgio Bavestrello 《水产资源保护:海洋与淡水生态系统》2021,31(3):543-566
- Seamounts host some of the most important deep-sea ecosystems. The unique environmental characteristics of seamounts sustain rich biological hot spots, which, in recent times, have suffered the effects of intense fishing pressure.
- Biodiversity and vulnerability data are extremely scarce for Mediterranean seamounts, and this, in addition to the complex socio-economic and juridical status of offshore sites, results in difficulty in identifying the best management strategies.
- An extensive remotely operated vehicle (ROV) survey was used to characterize the megabenthic assemblages of the summits of two upper bathyal seamounts, Ulisse and Penelope (Ligurian Sea, north-west Mediterranean Sea). The biogeographic implications of these findings and the possible environmental factors favouring the occurrence of these communities are discussed.
- High densities of abandoned, lost, or otherwise discarded fishing gear (mainly longlines) and a reduction in the average size of the fragile and slow-growing habitat-forming gorgonian Callogorgia verticillata indicate the occurrence of high levels of anthropogenic impacts on the summit regions, which are fishing grounds for artisanal and recreational fishers.
- The recovery of fishing data describing the first catches in the 1970s proved to be useful in inferring the short- and long-term effects of fishing practices in these previously unexploited offshore areas. In particular, the local extinction of demersal top predators, subjected to exceptional catches nearly 50 years ago, highlights the slow recovery rate of such species.
- Criteria defining vulnerability are discussed for the two study areas, and specific conservation actions, including the creation of regulated protected areas, are proposed.
44.
45.
Corti Martina Cavalli Daniele Cabassi Giovanni Vigoni Antonio Degano Luigi Marino Gallina Pietro 《Precision Agriculture》2019,20(4):675-696
Precision Agriculture - The development of small unmanned aerial vehicles and advances in sensor technology have made consumer digital cameras suitable for the remote sensing of vegetation. In this... 相似文献
46.
47.
Weak effects of habitat type on susceptibility to invasive freshwater species: an Italian case study 下载免费PDF全文
Angela Boggero Alberto Basset Martina Austoni Enrico Barbone Luca Bartolozzi Isabella Bertani Alessandro Campanaro Antonella Cattaneo Fabio Cianferoni Giuseppe Corriero Ambrosius Martin Dörr A. Concetta Elia Gentile Francesco Ficetola Lyudmila Kamburska Gianandrea La Porta Sara Lauceri Alessandro Ludovisi Elda Gaino Enzo Goretti Massimo Lorenzoni Marina Manca Aldo Marchetto Giuseppe Morabito Francesco Nonnis Marzano Alessandro Oggioni Cataldo Pierri Nicoletta Riccardi Giampaolo Rossetti Nicola Ungaro Pietro Volta Silvia Zaupa Diego Fontaneto 《水产资源保护:海洋与淡水生态系统》2014,24(6):841-852
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48.
Sandra Wenger Désirée Müllhaupt Stefanie Ohlerth Sarah Prasse Karina Klein Bianca da Silva Valente Martina Mosing 《Veterinary anaesthesia and analgesia》2017,44(3):529-537
Objective
To compare airway management during induction of anaesthesia, spontaneous ventilation (SV) and controlled mechanical ventilation (CMV), using an endotracheal tube (ETT), laryngeal mask (LM), rabbit-specific supraglottic airway device (v-gel) or facemask (FM).Study design
Prospective randomized crossover experiment.Animals
Ten New Zealand White rabbits.Methods
After premedication, rabbits were randomly allocated to four groups: 1) ETT; 2) LM; 3) v-gel or 4) FM. The required dose of propofol, duration and number of attempts to place an airway device and leakage during SV and CMV at different peak inspiratory pressures (6, 10, 12, 14 and 16 cmH2O) were recorded. Computed tomography (CT) of the head, neck and abdomen were performed before and after CMV.Results
Significantly less propofol and time [2.0 ± 0.5 mg kg?1, 82 ± 34 seconds, p < 0.001] were needed to place the FM compared to the three other groups [v-gel 5.1 ± 2.1 mg kg?1, 302 ± 124 seconds; LM 4.8 ± 1.2 mg kg?1, 275 ± 89 seconds; ETT 5.5 ± 1.4 mg kg?1, 315 ± 147 seconds]. A leak > 25% of the tidal volume occurred at the lowest pressure in FM [median (range), 6 (6–8) cmH2O], which was significantly lower than with v-gel [16 (6–no leak at 16) cmH2O], LM [>16 (6–no leak at 16)] or ETT [>16 (no leak at 16) cmH2O] (p < 0.001). On CT images, the height and width of the larynx were significantly smaller with v-gel in comparison to FM and LM (p = 0.004). A significant increase in the amount of gas in the stomach (p = 0.007), but not gastric volume, was detected in FM and LM.Conclusions and clinical relevance
The v-gel is a practical alternative to LM and ETT for airway management and CMV, but can compress the larynx. The FM is easily placed, but significant leakage occurs during CMV. 相似文献49.
Piviani M Segura D Monreal L Bach-Raich E Mesalles M Pastor J 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2011,40(3):340-344
Background: Two neutrophilic indices reported by the ADVIA 120 Hematology Analyzer, neutrophilic myeloperoxidase index (MPXI), and mean light absorbance (neutrophil X mean [NXM]) have been proposed as indicators of systemic inflammatory disease in horses and of neutrophil activation in coronary ischemic syndromes in people. Objective: The aim of this study was to evaluate NXM and MPXI in healthy, sick nonseptic, and sick septic foals to determine whether conditions likely associated with neutrophil activation result in decreases in these variables. Methods: In this retrospective study, CBC data from 61 neonatal foals presented to the Equine Teaching Hospital of Barcelona were evaluated for correlations between MPXI, NXM, percentage of large unstained cells, neutrophil count, and percentage of band neutrophils. Results obtained in septic (n=32), sick nonseptic (n=22), and healthy foals (n=7) were compared. In addition, results recorded in septic/neutropenic (n=12), septic/non‐neutropenic (n=20), nonseptic/neutropenic (n=8), nonseptic/non‐neutropenic (n=14), and healthy foals (n=7) were also compared. Results: A weak negative correlation was found between MPXI and neutrophil count and between NXM and percentage of band neutrophils. Septic/neutropenic foals had significantly higher MPXI values (median 17.9, minimum–maximum 4.7–42.5) than did septic/non‐neutropenic (1.5, ?24.4 to 22.3), nonseptic/neutropenic (6.6, 0.6–17.9), and nonseptic/non‐neutropenic foals (8.8, ?10.1 to 16.8) but did not differ significantly from controls (12.8, ?8.5 to 20.4). Conclusions: Significant differences in NXM or MPXI were not found when disease groups were compared with controls; however, septic/neutropenic foals had significantly higher median MPXI than other groups of sick foals. Further prospective studies are needed to clarify if this finding is related to decreased neutrophil function or activation in septic/neutropenic foals. 相似文献
50.
Hafezparast M Klocke R Ruhrberg C Marquardt A Ahmad-Annuar A Bowen S Lalli G Witherden AS Hummerich H Nicholson S Morgan PJ Oozageer R Priestley JV Averill S King VR Ball S Peters J Toda T Yamamoto A Hiraoka Y Augustin M Korthaus D Wattler S Wabnitz P Dickneite C Lampel S Boehme F Peraus G Popp A Rudelius M Schlegel J Fuchs H Hrabe de Angelis M Schiavo G Shima DT Russ AP Stumm G Martin JE Fisher EM 《Science (New York, N.Y.)》2003,300(5620):808-812
Degenerative disorders of motor neurons include a range of progressive fatal diseases such as amyotrophic lateral sclerosis (ALS), spinal-bulbar muscular atrophy (SBMA), and spinal muscular atrophy (SMA). Although the causative genetic alterations are known for some cases, the molecular basis of many SMA and SBMA-like syndromes and most ALS cases is unknown. Here we show that missense point mutations in the cytoplasmic dynein heavy chain result in progressive motor neuron degeneration in heterozygous mice, and in homozygotes this is accompanied by the formation of Lewy-like inclusion bodies, thus resembling key features of human pathology. These mutations exclusively perturb neuron-specific functions of dynein. 相似文献