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431.
Albarellos GA Montoya L Waxman S Kreil V Ambros LA Hallu R Rebuelto M 《Veterinary journal (London, England : 1997)》2006,172(2):334-339
The aims of this study were to assess the pharmacokinetics and pharmacokinetic/pharmacodynamic (PK/PD) indices predictive of clinical outcome of ciprofloxacin (CIP) and norfloxacin (NOR) after multiple oral dosing, and to investigate their penetration into prostatic fluid in dogs. Eight dogs received seven oral doses b.i.d. of NOR (20 mg/kg) and CIP (15 mg/kg). Drug concentrations were determined in blood and in two prostatic fluid samples. Prostatic fluid concentrations were lower than plasma concentrations for both drugs. No statistically significant differences were determined between the pharmacokinetic parameters calculated after the first and seventh doses for either CIP or NOR. The PK/PD indices were found to be useful for predicting bacteriological outcome for fluoroquinolones (area under the disposition curve/minimum inhibitory concentration [MIC] and peak plasma concentration/MIC) and indicate that with this dose regimen CIP presents a more favourable disposition than NOR for successful clinical outcome. 相似文献
432.
Lisboa AC Mello IC Nunes RS Dos Santos MA Antoniolli AR Marçal RM Cavalcanti SC 《Fitoterapia》2006,77(6):439-442
Oral administration of hexanes, chloroform, and ethyl acetate extracts of the leaves of Hyptis pectinata significantly reduced the number of writhing induced by acetic acid and increased the response to thermal stimuli in hot-plate test. Such effect was completely reversed by the opioid antagonist naloxone. 相似文献
433.
O. Tomazelli Júnior F. Kuhn P. J. Mendonça Padilha C. Nunes Nesi M. Mestres J. Dal Magro S. De Lamo Castellví 《Aquaculture International》2018,26(6):1459-1468
The present work was performed to investigate if feeding Litopenaeus vannamei with microencapsulated thyme essential oil (TEM, 1.05 g thyme essential oil per 100-g powder) adsorbed on commercial pellet feed was able to protect shrimps against white spot syndrome virus (WSSV) disease. Five treatments were tested: uninfected shrimp fed with commercial pelleted feed (TC, negative control), WSSV-infected shrimp fed with commercial pelleted feed (T1, positive control), WSSV-infected shrimp fed with commercial pelleted feed with 0.1% TEM (T2), WSSV-infected shrimp fed with commercial pelleted feed with 0.5% TEM (T3), and WSSV-infected shrimp fed with commercial pelleted feed with 1% TEM (T4). At 72 h post infection, phenoloxidase activity of shrimps treated with 1% TEM did not show significant differences with TC values but it was significantly higher than that of the other treatments (T1, T2, and T3). Moreover, shrimps treated with T4 presented absence of clinical signs of WSSV infection and their survival rate was significantly higher than that of T1, T2, and T3 treatments. Therefore, 1% TEM seemed to protect shrimps against WSSV symptoms. Using microencapsulated thyme essential oil may help to fight against WSSV in shrimp farms. 相似文献
434.
Tamara Ponchon Mariana Lopez Merlo Marcela Faya Marcelo Priotto Claudio Barbeito Cristina Gobello 《Journal of veterinary science (Suw?n-si, Korea)》2016,17(1):111-113
To assess the effects of a single supraphysiological postnatal administration of a progestogen on uterine glands in dogs, 10 females were randomly assigned to a medroxyprogesterone acetate 35 mg (MPA; n = 6) or placebo (n = 4) group within the first 24 h of birth. The safety of the treatment was also evaluated. A transient mild clitoris enlargement appeared in MPA-treated females. Microscopic postpubertal uterine assessment revealed the presence of uterine glands in all cases without significant differences in the area occupied by the glands per µm2 of endometrium nor in the height of the uterine epithelium. 相似文献
435.
Brayan Allan R. Massaroli Joisiane Mendes Araújo Jean C. G. Ortega André Valle Nunes Lúcia Mateus Samuel Elias Silva Jerry Penha 《Fisheries Management and Ecology》2021,28(4):328-337
Fisheries are the most common ecosystem service that fish provide to human populations, yet recreational fisheries are often overlooked when evaluating such services. Here, the socioeconomic profiles of fishers, the composition of their catches and catch per unit effort (CPUE) are described, to estimate the economic value of the recreational fishery on a stretch of the Cuiabá River in the Brazilian Pantanal. Questionnaires were used to obtain socioeconomic information and fishing yield from fishers for 2013 and 2014. Additionally, a census on the number of fishers and fishing platforms along the sampled region was conducted in 2018. This recreational fishery mostly involves middle class adult males, based mostly in the Cuiabá city metropolitan region. They invested, on average, US$41.1 (SD = US$16.5, median = $35.2) per fishing visit, catching around 19 fish species. Overall, mean CPUE from the recreational fishery was 42.20 fish/fisher.day (17.4 kg/fisher/day). Annual economic value of this recreational fishery was estimated at around US$1.8 million, which highlights the importance of this activity to the local economy. Greater environmental conservation efforts are recommend to ensure the long-term viability of this ecosystem service. 相似文献
436.
A. S. F. Araújo E. F. L. Silva L. A. P. L. Nunes R. F. V. Carneiro 《Land Degradation \u0026amp; Development》2010,21(6):540-545
The aim of this work was to investigate the effect of converting native savanna to Eucalyptus grandis forest on soil microbial biomass in tropics. Soil samples were collected from three sites: undisturbed native savanna (savanna), the site of a 1‐year‐old E. grandis forest (1 y), and the site of a 2‐year‐old E. grandis forest (2 y). Soil microbial biomass C (MBC), basal respiration, substrate induced respiration (SIR), soil organic carbon (SOC), microbial, and respiratory quotients were evaluated in soil samples collected from 0–20 cm depth. One year converted forest caused a significant reduction in MBC, SIR, and microbial quotient (about 70, 65 and 75 per cent, respectively). However, after 2 years of E. grandis forest growth, there was recovery of these variables. Soil basal respiration and respiratory quotient were significantly higher in 1 y forest (about 4 and 14 times, respectively) than in savanna. The results showed a significant decrease, after 2 years, in soil respiration and respiratory quotient, suggesting a recovery of soil microorganisms as time passes. In the short term, our results showed negative changes in soil microbial biomass following the conversion of native savanna to E. grandis. Copyright © 2010 John Wiley & Sons, Ltd. 相似文献
437.
Patrícia de Mello Papa Priscilla Nascimento Guasti Bruna De Vita Nathalia Genú Nakazato Leandro Maia Camila de Paula Freitas Dell’Aqua Verônica Flores da Cunha Scheeren Lorenzo Garrido Teixeira Martini Segabinazzi Luiz Roberto Pena de Andrade Junior Luis Fernando Mercês Chaves Silva Endrigo Adonis Braga Araújo Sidnei Nunes Oliveira Frederico Ozanam Papa Fernanda da Cruz Landim-Alvarenga Marco Antonio Alvarenga 《Reproduction in domestic animals》2020,55(4):429-437
Although stem cell therapy is a promising alternative for treatment of degenerative diseases, there are just few reports on the use of stem cells therapy in horse's reproductive system. This study aims to evaluate the effect of intratesticular injection of bone marrow mesenchymal stromal/stem cells (MSCs) in healthy stallions, and its outcome on seminal parameters and fertility. In Experiment 1, 24 stallions were divided into treatment group (TG) and control group (CG). In the TG, an intratesticular application of MSC was performed, and in the CG, only PBS was used. Measurements of testicular volume, surface temperature and Doppler ultrasonography were performed 24 and 48 hr after treatments. Fifteen days after application, the testicles were removed and submitted to histological analysis. In Experiment 2, 3 fertile stallions received similarly treatment with MSCs. Physical examination and sperm analysis were performed weekly during 60 days after treatment, and at the end, semen from one of them was used for artificial inseminations of 6 healthy mares. In Experiment 1, clinical examinations showed no signals of acute inflammation on both groups according to the analysed variables (p > .05). Also, no signal of chronic inflammation was observed on histological evaluation. In Experiment 2, stallions presented no physical alterations or changes in sperm parameters, and a satisfactory fertility rate (83%; 5/6) was observed after AI. The results support the hypothesis that intratesticular application of bone marrow MSCs is a safe procedure, and this could be a promising alternative to treat testicular degenerative conditions. 相似文献
438.
Kubec R Hrbácová M Musah RA Velísek J 《Journal of agricultural and food chemistry》2004,52(16):5089-5094
Precursors involved in the formation of pink and green-blue pigments generated during onion and garlic processing, respectively, have been studied. It has been confirmed that the formations of both pigments are of very similar natures, with (E)-S-(1-propenyl)cysteine sulfoxide (isoalliin) serving as the primary precursor. Upon disruption of the tissue, isoalliin and other S-alk(en)ylcysteine sulfoxides are enzymatically cleaved, yielding 1-propenyl-containing thiosulfinates [CH3CH=CHS(O)SR; R = methyl, allyl, propyl, 1-propenyl] among others. The latter compounds have been shown to subsequently react with amino acids to produce the pigments. Whereas the propyl, 1-propenyl, and methyl derivatives form pink, pink-red, and magenta compounds, those containing the allyl group give rise to blue products after reacting with glycine at pH 5.0. The role of other thiosulfinates [RS(O)SR'] (R, R' = methyl, allyl, propyl) and (Z)-thiopropanal S-oxide (the onion lachrymatory principle) in the formation of the pigments is also discussed. 相似文献
439.
440.
Alexandre Mendes Amude Selwyn Arlington Headley Amauri Alcindo Alfieri Suely Nunes Esteves Beloni Alice Fernandes Alfieri 《Journal of veterinary science (Suw?n-si, Korea)》2011,12(4):409-411
This report describes the naturally occurring atypical neuropathological manifestation of systemic canine distemper virus (CDV) infection in two 16-day-old Pit Bull pups. CDV-induced changes affected the gray and white matter of the forebrain while sparing the hindbrain. Histologically, there was necrosis with destruction of the nervous parenchyma due to an influx of inflammatory and reactive cells associated with eosinophilic intranuclear inclusion bodies within glial cells. Positive immunoreactivity against CDV antigens was predominantly observed within astrocytes and neurons. RT-PCR was used to amplify CDV-specific amplicons from brain fragments. These findings suggest the participation of CDV in the etiopathogenesis of these lesions. 相似文献