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61.
Antimicrobial activity of Memecylon malabaricum leaves 总被引:4,自引:0,他引:4
The petroleum ether, chloroform and methanol extracts of Memecylon malabaricum leaves were tested for antimicrobial activity. Only methanol extract has shown activity against bacteria both Gram (+) and Gram (-), and fungi. 相似文献
62.
A new phorbol diester, 13-O-myristyl-20-O-acetyl-12-deoxyphorbol (1), has been isolated from the benzene extract of the heartwood of Aleurites moluccana. In addition, hentriacontane, 6,7-dimethoxycoumarin, 5,6,7-trimethoxycoumarin and beta-sitostenone are being reported for the first time from this species. 相似文献
63.
Prosopis cineraria (L.) Druce, commonly known as Jandi, is a deep rooted, nitrogen fixing, multipurpose tree endemic to the hot deserts of India. These trees are the essential component of the agroforestry land use system in these parts of India. The shade-intolerant tree reproduces poorly in nature and is difficult to propagate vegetatively. Germination up to 86.6% was observed after 15 days in seeds soaked in water at room temperature for 72 h. In another treatment, pouring of boiling water twice (at 0 and 6 h) over seeds and germinating after 12 h produced germination rates of 92.6%. Field establishment of containerized transplants in polythene bags (22×10 cm; 150 gauge) gave 90.3% survival after 6 months and 75.4% survival after 24 months. Seedlings were irrigated once during transplanting with 15 1 water. Bare root transplants and manual direct seeding after 6 months had a survival of 30.8 and 45.0%, respectively. Increased levels of nutrients (N, P and K), moisture content and organic carbon were observed under plantations as compared to open areas. 相似文献
64.
Cassia occidentalis L. is an annual or perennial Ayurvedic plant which is used in several traditional medicines to cure various diseases. This weed has been known to possess antibacterial, antifungal, antidiabetic, anti-inflammatory, anticancerous, antimutagenic and hepatoprotective activity. A wide range of chemical compounds including achrosin, aloe-emodin, emodin, anthraquinones, anthrones, apigenin, aurantiobtusin, campesterol, cassiollin, chryso-obtusin, chrysophanic acid, chrysarobin, chrysophanol, chrysoeriol etc. have been isolated from this plant. The presented review summarizes the information concerning the botany, ethnopharmacologyquery, phytochemistry, biological activity and toxicity of the C.occidentalis plant. 相似文献
65.
Phenolic glycosides from Dodecadenia grandiflora and their glucose-6-phosphatase inhibitory activity
Manmeet Kumar Preeti Rawat Mohammad Faheem Khan Akhilesh K. Tamarkar Arvind K. Srivastava Kamal R. Arya Rakesh Maurya 《Fitoterapia》2010
Phytochemical investigation of Dodecadenia grandiflora leaves led to the isolation and identification of three phenolic glycosides, designated 1-[(4′-O-(E)-p-coumaroyl)-β-d-glucopyranosyl]-oxy-2-phenol (1), 1-[(6′-O-(E)-p-coumaroyl)-β-d-glucopyranosyl]-oxy-2-phenol (2) and 1-[O-β-d-glucopyranosyl(1→2)-β-d-glucopyranosyl]-oxy-2-phenol (3), along with nine known compounds. Compounds 1, 2, 5 and 9 exhibited significant glucose-6-phosphatase inhibitory activity (63.7, 66.9, 82.9 and 85.4%) with IC50 values of 88.5, 81.0, 51 and 50 μM respectively. On the basis of biological results, a structure–activity relationship has been discussed. 相似文献
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In the present study, we are reporting permeability and pharmacokinetics of nobiletin in rat plasma and brain, using a validated reverse phase high performance liquid chromatographic method. Protein precipitation method was used for the extraction of nobiletin and coumarin (IS) from rat plasma and brain tissue. The system was run in isocratic mode with mobile phase consisting of potassium dihydrogen ortho-phosphate (pH 4.5; 0.04 mM) and acetonitrile in ratio of 50:50, v/v. The total chromatographic run time was 9.0 min. The method was proved to be accurate and precise at linearity range of 0.05–10 μg/mL with a correlation coefficient (r) of ≥ 0.994 in rat plasma and ≥ 0.995 in rat brain. The intra- and inter-day precision and accuracy values are found to be within the assay variability limits as per the FDA guidelines. Nobiletin was found stable in the battery of stability studies viz., bench-top, auto-sampler, freeze/thaw cycles and long term storage in a freezer at − 70 ± 10 °C. Maximum concentrations of nobiletin in both plasma and brain were observed at 1 h after single oral dosing (50 mg/kg). The maximum concentration in plasma and brain were 1.78 and 4.20 μg/mL, respectively. The AUC0–t in plasma and brain were 7.49 and 20.66 μg·h/mL, respectively. The mean elimination half life (t1/2) in plasma and brain were 1.80 and 11.42 h, respectively. The Parallel Artificial Membrane Permeability Assay (PAMPA) permeability of nobiletin was found to be high at both pH 4.0 and 7.0. 相似文献
68.
Vivek Ahluwalia Ritu Sisodia Suresh Walia Om P. Sati Jitendra Kumar Aditi Kundu 《Journal of pest science》2014,87(2):341-349
Essential oils from inflorescences and roots of Eupatorium adenophorum Spreng (Asteraceae) have been investigated for their antimicrobial, phytotoxic and antioxidant activities. Based on GC–MS, the oil from inflorescences is dominated by sesquiterpenes (55.9 %) with γ-cadinene (18.4 %), γ-muurolene (11.7 %), 3-acetoxyamorpha-4,7(11)-diene-8-one (7.4 %) and bornyl acetate (6.3 %) as the major constituents. The oil obtained from the roots contained both sesquiterpenes (34.3 %) and monoterpenes (32.5 %) in almost equal proportions with E,E-cosmene (19.9 %), γ-muurolene (10.1 %), isothymol (7.5 %), β-cadinene (7.0 %) and α-phellandren-8-ol (5.9 %) as the major constituents. Both oils exhibited significant antifungal activity against five phytopathogenic fungi. The inflorescence oil showed higher antibacterial activity against Klebsiella pneumoniae, while the root oil was more effective against Staphylococcus aureus. The oils strongly inhibited or delayed germination and seedling growth of the weed Phalaris minor in a dose-dependent manner. As evidenced by a DPPH assay, the essential oils also exhibited significant free radical scavenging activity. 相似文献
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