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排序方式: 共有181条查询结果,搜索用时 15 毫秒
61.
Fatemeh Zarei Namdar Yousofvand Mozafar Khazaei Ali Ghanbari 《Iranian Biomedical Journal》2013,17(4):221-224
Background: The secretion of thyroxin (T4) as the main hormone of thyroid gland is regulated by androgens. The present study aimed to evaluate the effect of testosterone and finasteride administration and castration on serum levels of T4 and to show the effect of this regulation on total body weight, weight of testis, and the weight of prostate. Methods: Male adult rats (n = 32) were divided into 4 groups (n = 8): Group 1 (control), Group 2 (castration), Group 3 (finasteride: 20 mg/kg/day) and Group 4 (testosterone: 5 mg/kg/day). At the end of the study (35 days), serum level of thyroxin, body weight, weight of testis, and prostate were determined. Results: The data showed that the body weight increased in castrated (P = 0.04) and decreased in testosterone (P = 0.00) groups but did not differ in finasteride (P>0.05) group. There were not any differences in the weight of testis among control, finasteride, and testosterone groups but the weight of prostate increased in testosterone group (P = 0.00) and decreased in castrated (P = 0.03) and finasteride groups (P = 0.04). In addition, the serum level of T4 (nmo/ml) decreased in the three groups: finasteride (P = 0.03), testosterone (P = 0.04), and castrated (P = 0.00). Conclusion: Testosterone in both high and low levels decreased the amount of T4 with a time-dependent manner. Key Words: Finasteride, Rats, Testosterone, Thyroxin 相似文献
62.
Melissa A. Fitzgerald Christine J. Bergman Adoracion P. Resurreccion Jürgen Mller Rosario Jimenez Russell F. Reinke Margrit Martin Pedro Blanco Federico Molina Ming‐Hsuan Chen Victoria Kuri Marissa V. Romero Fatemeh Habibi Takayuki Umemoto Supanee Jongdee Eduardo Graterol K. Radhika Reddy Priscila Zaczuk Bassinello Rajeswari Sivakami N. Shobha Rani Sanjukta Das Ya Jane Wang Siti Dewi Indrasari Asfaliza Ramli Rauf Ahmad Sharifa S. Dipti Lihong Xie Nguyen Thi Lang Pratibha Singh Dmaso Castillo Toro Fatemeh Tavasoli Christian Mestres 《Cereal Chemistry》2009,86(5):492-498
Amylose content is a parameter that correlates with the cooking behavior of rice. It is measured at the earliest possible stages of rice improvement programs to enable breeders to build the foundations of appropriate grain quality during cultivar development. Amylose is usually quantified by absorbance of the amylose‐iodine complex. The International Network for Quality Rice (INQR) conducted a survey to determine ways that amylose is measured, reproducibility between laboratories, and sources of variation. Each laboratory measured the amylose content of a set of 17 cultivars of rice. The study shows that five different versions of the iodine binding method are in use. The data show that repeatability was high within laboratories but reproducibility between laboratories was low. The major sources of variability were the way the standard curve was constructed and the iodine binding capacity of the potato amylose used to produce the standard. Reproducibility is much lower between laboratories using a standard curve of potato amylose alone compared with those using calibrated rice cultivars. This study highlights the need to standardize the way amylose is measured, and presents research avenues for doing so. 相似文献
63.
Abdullah Darzi-Naftchali Ali Shahnazari Fatemeh Karandish 《Archives of Agronomy and Soil Science》2016,62(11):1554-1566
This research was conducted to quantify total phosphorus (TP) losses in poorly drained-consolidated paddy fields equipped with different surface and shallow subsurface drainage systems including drain depth of 0.9 m and drain spacing of 30 m (D0.9L30), drain depth of 0.65 m and drain spacing of 30 m (D0.65L30), drain depth of 0.65 m and drain spacing of 15 m (D0.65L15), drain spacing of 15 m and drain depths of 0.65 and 0.9 m as alternate depths (Bilevel). Typical surface drainage system of consolidated paddy fields was also considered as conventional practice of the study area (control). The subsurface drained fields were under year-round crop production of rice-canola, while the surface drained fields experienced only rice cropping once a year. During three rice-canola-rice growing seasons, TP losses through drainage and leaching in the D0.9L30, Bilevel, D0.65L30, D0.65L15 and control treatments were respectively, 1.12, 0.98, 1.44, 1.53 and 24.48 kg ha?1, equivalent to about 3.9%, 3.4%, 5.1%, 5.3% and 85.7% of applied triple superphosphate fertilizer. In the rice growing seasons, TP losses through surface runoff were higher than those through subsurface drainage effluents. Shallow subsurface drainage systems were promising for the study area compared surface drainage as phosphorus risks were reduced by 79%, 77%, 64% and 57% through D0.9L30, Bilevel, D0.65L30 and D0.65L15, respectively. These results demonstrated that, by providing suitable condition for winter cropping, subsurface drainage systems can diminish concerns related to phosphorus losses from poorly drained paddy fields in the north of Iran. 相似文献
64.
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66.
Malekinejad Hassan Rahmani Fatemeh Bahrampour Kobra 《Tropical animal health and production》2010,42(6):1229-1234
Zearalenone (ZEA) as a mycoestrogen is found frequently in human foods and animal feeds. Its estrogenic effects depend on
its biotransformation fate including both first- and second-phase reactions, which are predominantly governed by hydroxylation
and glucuronidation, respectively. In this study, we investigate the hepatic biotransformation of ZEA in river buffalo. To
evaluate the hepatic biotransformation of ZEA, both subcellular fractions of the liver were prepared. ZEA was incubated with
intracellular subfractions in the presence of nicotinamide dinucleotide phosphate, and the products were determined by means
of high-performance liquid chromatography. Moreover, in the same frame of experiment and in the presence of uridine diphosphate
glucuronic acid, the rate of glucuronidation for substrate and products were estimated as well. We found that α-zearalenol
(α-ZOL) is the major hydroxylated hepatic metabolite of ZEA produced by both studied subcellular fractions. The enzymatic
kinetics analyses indicated that the α-ZOL and β-ZOL production by microsomal fraction were two- and three-fold higher than
those by postmitochondrial fraction, respectively. The calculated data showed that α-ZOL is conjugated with glucuronic acid
more than ZEA and β-ZOL, especially at the lower concentrations, which seems to be more applicable. Our data suggest that
unlike other domestic ruminants including cattle and sheep, the hepatic biotransformation of ZEA in river buffalo results
in bioactivation and formation of potent estrogenic metabolite. Moreover, at the relevant concentrations, the produced potent
estrogenic metabolite is entirely conjugated with glucuronic acid and, consequently, may cause the prolongation of presence
of the compound in the body due to enterohepatic cycle. 相似文献
67.
Fatemeh Davami Farnaz Eghbalpour Leila Nematollahi Farzaneh Barkhordari Fereidoun Mahboudi 《Iranian Biomedical Journal》2015,19(4):194-205
Background:
The optimization of bioprocess conditions towards improved growth profile and productivity yield is considered of great importance in biopharmaceutical manufacturing. Peptones as efficient sources of nutrients have been studied for their effect on media development; however, their role on metabolic pathway is not well understood.Methods:
In the present study, the effect of different concentration of peptones on a recombinant Chinese hamster ovary (CHO) cell line grown in three serum-free suspension cultures was determined. Six peptones of different origins and available amino acid profiles were investigated regarding their impact on cell growth, productivity, and metabolic pathways changes.Results:
In optimized feeding strategies, increases of 136% and 159% in volumetric productivity (for a low-nutrient culture media) and 55% (for a high-nutrient culture media) were achieved. Furthermore, particular sources of peptones with specific amino acid profile developed preferential results for each different culture medium. Two peptones, SoyA2SC and SoyE-110, were the only hydrolysates that showed production improvement in all three media. Casein Peptone plus Tryptone N1 and SoyA3SC showed different improved results based on their implemented concentration for each individual basal medium.Conclusion:
The amino acid profile of peptones may provide clues to identify the most effective feeding strategies for recombinant CHO cells.Key Words: CHO cells, Culture media, Peptones, Recombinant proteins 相似文献68.
Sohani NZ Shishehbor P Kocheili F 《Pakistan journal of biological sciences: PJBS》2008,11(7):1015-1020
Laboratory experiments were conducted to measure the functional and numerical responses of Eretmocerus mundus Mercet parasitizing cotton whitefly, Bemisia tabaci Gennadius. Parasitoids were isolated singly for 24 h in 5 cm petri dishes with either 5, 10, 20, 40, 60 or 100 second nymphal stages of B. tabaci. Results showed a typical type II functional response, with up to 43.2 hosts attacked when 100 hosts were provided. The rate of attack and handling time were 0.0465 and 0.3341 days, respectively. At above mentioned densities, the parasitoids lived an average of approximately 4 days. At host densities of < or =20 host/day, the total number of eggs laid was limited by the number of hosts available. Total fecundity was highest with an average of 196 eggs/female at density 100. 相似文献
69.
BACKGROUND: Trichophyton tonsurans is one of the dermatophyte fungi which invades the skin and hair of human. Several properties of this fungus have been investigated so far. However a few studies were carried out in the field of molecular biology of this fungus. In the present study, we tried to identify the Squalene epoxidase gene which is related to synthesis of ergosterol in this fungus. METHODS: Pairs of 23 and 24 nucleotides primers were designed from highly conserved regions of the similar genes in other fungi. Mentioned primers were utilized in PCR by using isolated genomic DNA of T. tonsurans whereas the PCR fragments were then sequenced. RESULTS AND CONCLUSION: Nucleotides (n = 558) have been sequenced from this new gene which encodes a polypeptide with 186 amino acids. Sequences comparison in gene data banks (NCBI, NIH) for this part of DNA and its deduced amino acid revealed significant homology with members of the eukaryotic Squalene epoxidase. 相似文献
70.
Naser Agh Mansour Torfi Mozanzadeh Fatemeh Jafari Farzaneh Noori Reza Jalili 《Aquaculture Research》2020,51(3):918-931
A 90‐day feeding trial was carried out to examine the influence of fish oil (FO) substitution with blends of vegetable oils (VOs) on reproductive efficiency of female brooders and fluctuation in fatty acid (FA) profile of embryos in Oncorhynchus mykiss. A basal diet was formulated in which 20% (80FO/20VO), 50% (50FO/50VO), 75% (25FO/75VO) and 100% (100VO) of FO were replaced by mixture of VO. Reproductive performance of brooders was not affected by drastic alternations in FA profile of diets. The level of saturated and monounsaturated FAs (MUFAs) significantly increased, whereas the levels of long‐chain polyunsaturated FAs (LC‐PUFAs), mainly docosahexaenoic acid, profoundly decreased during embryogenesis. The concentrations of MUFA and n?6 PUFA increased in the eggs with increasing the incorporation of VO mixture in diets; however, the concentration of LC‐PUFA and n?3/n?6 PUFA ratio decreased. Haematological parameters and humoral immune responses including total immunoglobulin content, lysozyme and alternative complement pathway activities in brooders fed with the experimental diets did not statically different. In summary, incorporating mixture of various VO sources especially linseed and sunflower oils as good sources of α‐linolenic and linoleic acids, respectively, along with low levels of residual fat from fish meal in diet suggested a good strategy for providing the appropriate essential FA requirements of O. mykiss brooders for their successful reproduction. 相似文献