Analysis on Sustained Release of Protein from Microcapsule Prepared by Alginate

The paper studies a drug deliversy system for protein and find the optimum preparation condition.Cross-linked alginate(Alg) microcapsule was used to prepare microcapsule for protein,using bovine serum album(BSA) as a model drug.Effect of different cations and content of protein on configuration,size and enveloped rate of microcapsule were investigated.It is shown that Ba-Alg microcapsule has steady configuration,homogeneous size and high-enveloped rate.Also electrophoresis of native BSA before microencapsulation and after microencapsulation is measured by(SDS-PAGE),it is found that no significant change is observed BSA integrity.Release of BSA from microcapsule in vitro presents sustained release in some extent,and initial burst effect is significantly obvious.Microenpsulation drug in alginate will be a wishful drug delivery system.     

Synthetic Assessment of Power Transformer Condition Based on Matter-element Theory

Condition assessment on power transformer is an important approach to improve reliability of transformer and provide proper decision-making for condition-based maintenance. For long, static assessment method used in the past has already not adapted to the development of modem electricity transmission and distribution technology. So based on the deficiency of fuzzy synthetic assessment method, matter-element synthetic assessment method is introduced. The method can evaluate transformer condition not only in quality but also in quantity. Because each index weight can be given fairly and fast through improved analytic hierarchy process, which need not carry on consistency chec accuracy of assessment can be improved. Examples analysis has proved that assessment method of power transformer condition based on matter-element theory is rational and effective.     

Engineering Calculation Mode Based on Reformative B/S Architecture

Engineering designed mode has entered a new stage because of the development of network. New calculating system based on network appeared. By analyzing the common B/S architecture, this paper brings forward an reformative architecture based on Web services and ASP. NET in order to build the new mode of engineering calculation. It can fully implement the sharing of the resources and provide the engineering designers a wonderful calculating environment, and the working eifficiency of designers can be enhanced.     

夏大豆齐黄29号配套栽培技术

齐黄29号是由山东省农业科学院作物研究所以济3045作母本、潍8640作父本有性杂交，经系谱选育而成的早熟、高产、高油、抗病虫夏大豆新品种，2003年通过国家审定（审定编号：国审豆2003019）。     

病态池的检查和维修技术

随着沼气建设的快速发展,病态池的数量也随之增多。本文就如何分辨沼气池和输气线路病态、确定病态沼气池的病态类型、查找病态池漏水漏气部位及维修病态池提出了具体的方法。     

Expression of cathepsin C and tumor necrosis factor-α in human coronary artery and their relationships with coronary heart disease

AIM To explore the possible mechanism of cathepsin C （CTSC） and tumor necrosis factor-α （TNF-α） in coronary heart disease （CHD） by detecting the protein expression of CTSC and TNF-α in human coronary artery tissue. METHODS The coronary artery tissues from 52 cases of CHD and 25 cases of accidental death without any heart disease in the Forensic Judicial Expertise Center of Guizhou Medical University from October 2018 to December 2019 were collected as CHD group and control group, respectively. The coronary artery stenosis and intimal plaque formation were examined by histopathology, the protein expression of CTSC and TNF-α was determined by Western blot, and the intracellular expression of CTSC and TNF-α was analyzed by immunohistochemical staining. RESULTS The results of HE staining showed that the intima of coronary artery in control group was smooth, and no thickening or stenosis was observed. In CHD group, the intima thickened irregularly, atherosclerotic plaques formed, the intima became thinner and the lumen showed eccentric stenosis in varying degrees （P<0.05）. The results of Western blot showed that the expression of CTSC and TNF-α in CHD group was significantly higher than that in control group （P<0.05）. Immunohistochemical staining showed that both CTSC and TNF-α were expressed in the cytoplasm of foam cells, and their positive expression was significantly higher than that in control group （P<0.05）. The results of Pearson moment correlation analysis showed that there was positive correlation between the expression of CTSC and TNF-α in CHD （r²=0.743, P<0.05）. CONCLUSION The up-regulated expression of CTSC in coronary artery tissue may promote the expression of TNF-α and affect the occurrence and development of CHD.     

医学院校图书馆读者信息需求调查与分析

对川北医学院读者的文献信息需求进行了问卷调查,对调查结果进行了定量统计和定性分析,同时基于读者文献信息需求特点、需求规律及其影响因素等对该院图书馆文献资源建设提出了一些建议。     

联苯肼酯与2种杀螨剂复配对柑橘全爪螨的联合毒力

柑橘全爪螨是一种世界性害螨, 目前对许多药剂已经产生抗性。药剂复配是治理抗性问题, 延长药剂使用寿命的重要手段。为筛选出增效明显的复配新产品, 本文选取联苯肼酯作为标准药剂, 与阿维菌素和氟啶胺分别进行复配, 并采用叶碟喷雾法测定其联合毒力及增效作用。结果表明, 联苯肼酯、阿维菌素和氟啶胺的单剂LC50分别为16.43、0.29 mg/L和12.63 mg/L。联苯肼酯与阿维菌素复配比例为19∶1和15∶5的共毒系数分别为135.02和158.40, 具有增效作用。联苯肼酯与氟啶胺在6∶4、7∶3、5∶5、9∶1、8∶2复配比例的共毒系数分别为466.28、410.61、370.22、311.15和275.85, 增效作用显著。     

新疆干旱半干旱农田应用0.2%莪术醇饵剂防治害鼠的效果

为了解0.2%莪术醇饵剂在新疆干旱半干旱农田应用的可行性,2022年4月至7月, 在新疆博州温泉县进行了该药防治害鼠试验。施药在3个试验点(即3个重复)进行, 在害鼠繁殖高峰期前施药, 投放药饵后30、60 d和90 d调查防控效果。结果显示:3个试验区域的结果趋势相似, 校正灭效基本维持在50%以上。与空白对照区相比, 优势鼠种灰仓鼠与根田鼠试验投饵区的雌鼠怀孕率明显下降, 小家鼠、灰仓鼠平均胎仔数明显降低, 小家鼠、灰仓鼠和根田鼠施药区域的鼠类个体的亚成体比例与对照区域明显下降, 说明该药剂对当地害鼠的繁殖具有明显的控制作用, 可达到控制害鼠数量的目的, 适口性也较好, 可以在当地推广应用。