排序方式: 共有66条查询结果,搜索用时 15 毫秒
31.
LAUREN E. ABBITT LLOYD E. DAVIS † CAROL A. NEFF DAVIS 《Journal of veterinary pharmacology and therapeutics》1978,1(4):299-308
The effect of carbon tetrachloride (CT) induced toxic hepatitis on the pharmacokinetics of sodium salicylate was studied in beagle dogs. Plasma concentrationtime profiles were determined for sodium salicylate in ten healthy dogs and in the same dogs after CT administration. Laboratory tests for liver disease were performed before and after liver injury in order to examine the feasibility of using commonly employed laboratory tests as a guide for determining dosage regimens of sodium salicylate in the presence of liver dysfunction. The disappearance of sodium salicylate from the plasma of dogs was a first-order process through 8 h in both the normal and liver disease states. After CT, there was an alteration in the kinetic behavior between 8 and 24 h after salicylate administration. This change was linked to the decreased ability of the damaged liver to form glucuronides. The changes observed in the pharmacokinetics of salicylate before and after CT induced liver dysfunction were minimal and not statistically significant. The majority of the dogs, however, demonstrated a slightly decreased half-life after CT administration. This was due to an increase in the urinary excretion of unchanged salicylate. It was not possible to correlate laboratory parameters with pharmacokinetic parameters. Therefore, dosage alterations could not be based upon laboratory data. Data from this investigation, however, did not suggest the need to routinely alter the dosage of salicylate in the presence of CT induced toxic hepatitis. 相似文献
32.
The effects on clover and grass growth of five levels of ammonium nitrogen (NH4-N) applied before sowing, at sowing and after nodule initiation have been investigated. A pot experiment in which S184 white clover was grown in a peat soil showed that NH4-N up to 688 mg N per pot (approx. equivalent to a field rate of 120 kg ha-1 N) applied before sowing and at sowing did not affect clover growth. N-fixing activity (C2H2-reduction), on the other hand, was reduced progressively up to the highest level (688 mg N per pot). Application after nodule initiation increased growth relative to the zero-N treatment at all levels of application. Maximum growth and N fixation occurred at 516 mg N per pot where the DM yield was 70% higher than in the absence of added N. A field trial in which S184 clover and S24 perennial ryegrass were surface sown on to a peat soil showed an increase in grass and clover growth in the first year in response to 120 kg ha-1 N applied at sowing. Grass growth alone was increased at 120 kg ha -1 N applied 40 d before sowing. Lower rates of application before sowing and at sowing did not affect clover or grass growth. The effect of the delayed application of NH4-N on legume growth was less marked than that in the pot experiment, 90 kg ha-1 N stimulating clover growth by 40% in the first year. The effect was however different from that in the pot experiment, in that, whilst 30kg ha-1 N increased N fixation relative to the zero-N treatment, plants exposed to higher levels showed a depression in N-fixing capacity. N-fixation was correlated with nodule numbers in the delayed NH4-N application, the closest correlation being with the number of multilobed nodules which was highest at 30 kg ha-1 N and lowest at 120 kg ha-1 N. It is suggested that circumstances exist when the use of a relatively low starter N dressing (20–60 kg ha-1 N) at sowing would not increase clover or grass growth in the early stages of the establishment of a hill reseed. Under such circumstances higher rates of application (100 kg ha -1 N), preferably delayed until the seedlings are in a position to take up the nitrogen rapidly, would have the greatest effect. 相似文献
33.
ELIZABETH M. SANTSCHI dvm CAROL B. GRINDEM dvm PhD Diplomateacvp LLOYD P. TATE Jr vmd Diplomateacvs WAYNE T. CORBETT vmd DrPH 《Veterinary surgery : VS》1988,17(1):6-9
Ten student surgery ponies were subjected to exploratory laparotomy. Abdominal paracentesis was performed preoperatively and daily postoperatively for 6 days, then the ponies were euthanatized and necropsied. Initial baseline peritoneal fluid parameters were within established reference limits. Postoperatively, the total leukocyte count and total protein in the peritoneal fluid rose and remained elevated for the 6 days of the study. Complete blood counts (CBCs) were performed preoperatively and on days 1 and 4 postoperatively. On day 1, a stress leukogram with a mild inflammatory component developed, but by day 4, the CBCs were within normal limits. The mean plasma fibrinogen levels, which were determined daily, peaked on day 4. 相似文献
34.
Anal sac gland adenocarcinoma in the dog: 14 cases 总被引:2,自引:0,他引:2
Anal sac gland adenocarcinomas were identified in 14 dogs, 11 of which were female. The majority of the dogs were over 9 years old. Recurrence and metastasis to regional lymph nodes were common. Pseudo-hyper-parathyroidism may be seen in association with this tumour. 相似文献
35.
Artificial filariae, infused into the venous system in dogs, were preferentially distributed within the pulmonary arteries to the right side, in particular, the right caudal artery. These findings are discussed in relation to the distribution of natural filariae (D. immitis). 相似文献
36.
CHRISTINA M. ELLIS DVM TIMOTHY M. LYNCH DVM Diplomate ACVS DONNIE E. SLONE DVM Diplomate ACVS FAITH E. HUGHES DVM Diplomate ACVS CAROL K. CLARK DVM Diplomate ACVIM 《Veterinary surgery : VS》2008,37(8):786-790
Objective— To report complications and survival after large colon resection and end‐to‐end anastomosis in horses with strangulating large colon volvulus. Study Design— Retrospective case series. Animals— Horses (n=73) with strangulating large colon volvulus. Methods— Records (January 1995 to December 2005) of horses that had large colon resection and anastomosis for strangulating large colon volvulus were reviewed for complications. Follow‐up data were obtained by telephone questionnaire at least 1 year postoperatively. Cox proportional hazards model was used for multivariate association with survival time. Variables included admission date, age, temperature, heart rate, packed cell volume, total plasma protein concentration, white blood cell count, breed, and sex. Significance was set at P<.05. Results— The most common postoperative complication was diarrhea. None of the 9 variables of interest were significant for survival. Short‐term survival rate (to discharge) was 74%. Overall survival rates at 1, 2, and 3 years postoperatively were 67.8%, 66.0%, and 63.5%, respectively. Four horses died of colic in the first year after surgery. All horses surviving long‐term (>1 year) returned to their intended use (37 brood mares, 2 racehorses, and 1 show horse) with no chronic problems related to the surgical procedure. Conclusion— None of the variables examined were associated with survival. Outcomes were similar to other large studies of surgical colic in the horse. Self‐limiting diarrhea is common after large colon resection and the prognosis for survival after hospital discharge is favorable. Clinical Relevance— Horses that survive the early postoperative period and are discharged after large colon resection and anastomosis have a good chance for long‐term survival with minimal negative impact on quality of life and use. 相似文献
37.
38.
C. A. MARRIOTT 《Grass and Forage Science》1988,43(3):253-262
The seasonal variation in herbage mass and nitrogen fixing (acetylene reducing) activity of white clover in an upland sward, cut weekly to 3·5 cm from mid-May until mid-October, was measured. Acetylene reducing activity (ARA) was measured over a 24-h period at 3-weekiy intervals starting on 3 March 1983. Clover leaf and Stalon biomass was measured by harvest of the assay truces, and from mid-May quadrat euts to 3·5 cm above the soil surface provided estimates of herbage accumulation.
Little A RA was detected in March, but activity increased substantially after 10 cm soil temperatures reached > 3°C, and peak activity per unit of clover leaf dry weight occurred in June and July; standing clover leaf dry matter increased during the season to a maximum of 60·5 g m−1 in June. Acetylene reducing activity was positively correlated with the number of rooted nodes, and Stalon and leaf dry weights in early spring. Thereafter, except during a period of summer drought, ARA was positively correlated with the amount of clover leaf material.
Clover population density increased during the season and maximum growing point numbers (5540 m−1 ) occurred in September; maximum leaf number per unit area (12 984 m−1 ) was found in October, prior to the final cutting of the site.
Results suggest that higher levels of nitrogen fixation in upland swards should be obtained if sward management regimes, which encourage a high clover leaf area, are adopted. 相似文献
Little A RA was detected in March, but activity increased substantially after 10 cm soil temperatures reached > 3°C, and peak activity per unit of clover leaf dry weight occurred in June and July; standing clover leaf dry matter increased during the season to a maximum of 60·5 g m
Clover population density increased during the season and maximum growing point numbers (5540 m
Results suggest that higher levels of nitrogen fixation in upland swards should be obtained if sward management regimes, which encourage a high clover leaf area, are adopted. 相似文献
39.
Abstract. A microsporidian parasite was found in the gills of the brook trout, Salvelinus fontinalis (Mitchill), which was similar to Loma morhua Morrison and Sprague, a microsporidian parasite in the gills of cod. It was described and designated as Loma sp. Plistophora (=Pleistophora) salmonae Putz, Hoffman and Dunbar in gills of rainbow and steelhead trout, Salmo gairdneri Richardson, was also observed and was transferred to the genus Loma. All microsporidia known in gills of Gadidae and Salmonidae were judged to belong to the genus Loma but the data were not sufficient to provide a basis for a definitive separation of species. Provisionally, Loma morhua, L. branchialis, L. salmonae and Loma sp. were recognized. 相似文献
40.
The annual dormancy cycle was investigated in buried seeds of Polygonum aviculare L. exposed to natural temperature changes in Lexington, Kentucky, U.S.A. Seeds were exhumed monthly from December 1984 to February 1987 and tested in light (14-h daily photoperiod) and continuous darkness at 12/12-h daily alternating temperature regimes of 15/6, 20/10, 25/15, 30/15 and 35/20°C. During autumn and winter, seeds became non-dormant, and in March 1985 they germinated to 95-100% at all thermoperiods in light and to 7-61% in darkness. Seeds remained non-dormant during spring but became more specific in their germination requirements in early summer. During July and August 1985, seeds germinated to 17-53% in light at 30/15 and 35/20°C but to 0-10% at all other test conditions. By September, about 65% of the seeds were dormant, but the others were able to germinate under the higher alternating temperatures in light. A similar seasonal cycle was recorded in the following year through to the spring of 1987. The results confirm the seasonal pattern of dormancy in this species (Courtney, 1968) but indicate that alternating temperatures combined with light are important in determining germination potential in P. aviculare. 相似文献