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S. Gujja T.H. Terrill J.A. Mosjidis J.E. Miller A. Mechineni D.S. Kommuru S.A. Shaik B.D. Lambert N.M. Cherry J.M. Burke 《Veterinary parasitology》2013,191(1-2):51-58
Feeding sun-dried sericea lespedeza [SL; Lespedeza cuneata (Dum-Cours.) G. Don.] reduces gastrointestinal nematode (GIN) infection in goats fed in confinement, but effects of this forage when fed as a supplement to goats on pasture are unclear. A study was completed in which supplemental feeds (75 and 95% SL leaf meal pellets and a commercial pellet, all fed at 0.91 kg/head/day) were offered to thirty growing male Spanish goats (9 months old, 20.6 ± 2.8 kg, 10/treatment) grazing perennial warm-season grass pastures in Fort Valley, GA, from September to November, 2010. Fecal and blood samples were taken from individual animals weekly to determine fecal egg count (FEC) and packed cell volume (PCV), respectively, and animal weights were recorded at the start and end of the trial. After 11 weeks grazing, animals were slaughtered for recovery, counting, and speciation of adult GIN from the abomasum and small intestines. There was no difference in FEC between goats fed the 75 and 95% SL leaf meal pellets, but both groups had lower (P < 0.05) FEC than the goats fed the commercial pellets from days 35 to 77. The PCV values were not affected by the dietary treatments. Animal gain per day averaged 102.0, 77.2, and 53.3 g for goats fed 95% SL, commercial, and 75% SL pellets, respectively (P < 0.05). The 95% SL leaf meal pellet goats had 93.0 and 47.3% fewer (P < 0.05) total (male + female) adult Haemonchus contortus and Teladorsagia circumcincta, respectively, than control animals, while only male H. contortus were lower (47.6%; P < 0.05) in 75% SL-fed goats compared with commercial pellet-fed animals. Feeding supplemental SL leaf meal pellets improved animal performance (95% SL pellets) and reduced worm burdens (75 and 95% SL pellets) in young grazing goats and is a useful tool for natural GIN control in small ruminants. 相似文献
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Vettorato E Schöffmann G Burke JG Gibson AJ Clutton ER 《Veterinary anaesthesia and analgesia》2012,39(5):495-502
Objective To compare isoflurane and sevoflurane in lambs undergoing prolonged anaesthesia for spinal surgery. Study design Prospective randomised clinical study. Animals Eighteen Scottish blackface lambs 3–6 weeks of age and weighing 10–17 kg. Methods After intramuscular medetomidine, anaesthesia was induced and maintained with either isoflurane (group I) or sevoflurane (group S) delivered in oxygen. Meloxicam, morphine, a constant rate infusion of ketamine and atracurium were given intravenously (IV) during surgery. Lungs were ventilated to maintain normocapnia. with peak inspiratory pressures of 20–25 cmH2O. Ephedrine or dextran 40% was administered when mean arterial pressure (MAP) was <55 mmHg. Intrathecal morphine, and IV meloxicam and edrophonium were injected before recovery. Time to loss of palpebral reflex (TLPR) upon induction, cardiorespiratory variables, time at first swallowing and other movement, tracheal extubation, vocalisation, spontaneous head lifting (>1 minute), reunion with the ewe, and the number of MAP treatments were recorded. Statistical analysis utilised anova , Mann–Whitney, t‐test or Pearson’s correlation test as relevant. p < 0.05 was considered significant. Results End‐tidal carbon dioxide (mean ± SD) was significantly lower in group S (5.5 ± 0.6 kPa) than in group I (5.8 ± 0.5 kPa) while MAP (70 ± 11 mmHg) and diastolic arterial blood pressure (60 ± 11 mmHg) were higher in group S than in group I (65 ± 12 and 54 ± 11 mmHg, respectively). No differences were found with TLPR and MAP treatments. Time (median, range) from end of anaesthesia to ewe‐lamb reunion was briefer (p = 0.018) in group S (48, 20–63 minutes). Conclusion Isoflurane and sevoflurane are both suitable for maintaining general anaesthesia in lambs although sevoflurane, as used in this study, allows a more rapid reunion with the ewe. Clinical relevance The principal advantage of sevoflurane over isoflurane during prolonged anaesthesia in lambs is a more rapid recovery. 相似文献
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J. Turrel B. Burke S. Ullman M. McEntee R. Page 《Veterinary and comparative oncology》2005,3(1):52-53
Introduction: Greater than 50% of dogs with thyroid tumors present with surgically unresectable disease for which external beam radiotherapy has been reported to prolong survival. The success of 131 I for control of thyroid tumors in cats and in humans suggests such therapy may also play a role in the management of canine thyroid cancer.
Methods: Thirty‐nine dogs with WHO stage II/III (invasive or ectopic; n = 32) or IV (metastatic; n = 7) thyroid tumors were treated with131 I alone. Changes in thyroid function, 99M Tc‐pertechnetate (99M Tc) scintigraphic changes, and tumor response were recorded. Dogs with ventral cervical tumors were evaluated for feasibility of surgical resection following 131 I.
Results: Median overall survival was 839 days and 366 days for dogs with stage II/III and stage IV tumors, respectively. Thyroid hormone status, site and surgical resection were not associated with outcome in dogs with stage II/III tumors. Three dogs developed severe bone marrow suppression.
Conclusions: These findings suggest131 I should be investigated more thoroughly in dogs with thyroid tumors not considered surgical candidates to more clearly characterize the indications for therapy and followup recommendations. 131 I dosimetry in dogs with thyroid tumors remains problematic. Administration of 131 I is currently based on empiric recommendations and, in general, the treatment is well tolerated although additional studies are indicated to optimize response and minimize toxicity. 相似文献
Methods: Thirty‐nine dogs with WHO stage II/III (invasive or ectopic; n = 32) or IV (metastatic; n = 7) thyroid tumors were treated with
Results: Median overall survival was 839 days and 366 days for dogs with stage II/III and stage IV tumors, respectively. Thyroid hormone status, site and surgical resection were not associated with outcome in dogs with stage II/III tumors. Three dogs developed severe bone marrow suppression.
Conclusions: These findings suggest
197.
An experiment was completed to determine if copper oxide wire particles (COWP) had any effect on the activity of the nematode-trapping fungus Duddingtonia flagrans in growing lambs. COWP has been used recently as a dewormer in small ruminants because of nematode resistance to anthelmintics. D. flagrans has been used to control free-living stages of parasitic nematodes in livestock. Katahdin and Dorper lambs, 4 months of age, were administered no or 4 g COWP (n=24/dose) in early October 2003. Haemonchus contortus was the predominant gastrointestinal parasite during the trial, which was acquired naturally from pasture. Half the lambs from each COWP group were supplemented with corn/soybean meal with or without D. flagrans for 35 days. Fecal egg counts (FEC) and packed cell volume (PCV) were determined weekly between days 0 (day of COWP administration) and 35. Feces from lambs in each treatment group were pooled and three replicates per group were cultured for 14 days at room temperature. Larvae (L3) were identified and counted per gram of feces cultured. Treatment with COWP was effective in decreasing FEC, which remained low compared with FEC from lambs not treated with COWP. This led to an increase in PCV in these lambs (COWP x day, P<0.001). Number of larvae was decreased in feces from lambs treated with COWP and D. flagrans between days 14 and 35 compared to the other groups of lambs (COWP x D. flagrans x day, P<0.003). Percentage of larvae identified as H. contortus decreased in feces collected from lambs treated with COWP and D. flagrans between days 14 and 28 compared with other treatments (COWP x D. flagrans x day, P<0.05). Other trichostrongyles were present and remained less than 7% in feces collected from control lambs. There was no adverse effect of COWP on the ability of D. flagrans to trap residual larvae after COWP treatment. With fewer eggs being excreted due to the effect of copper on H. contortus, and the additional larval reducing effect exerted by the nematode destroying fungus D. flagrans, the expected result would be a much lower larval challenge on pasture when these two tools are used together in a sustainable control strategy. 相似文献
198.
L W George M L Tanner E L Roberson T M Burke 《Journal of the American Veterinary Medical Association》1981,179(8):820-822
A 6-year-old Thoroughbred gelding was examined because of respiratory disease that developed after it was placed on pasture occupied by a donkey. Clinical signs in the gelding included a harsh, dry paroxysmal cough and increased expiratory effort. Eosinophils were seen in smears of mucus aspirated from the trachea and the bronchi. Immature, 5th-stage Dictyocaulus arnfieldi was identified in the tracheal mucus. The cough and other clinical signs were not diminished by corticosteroid therapy or by the administration of bronchodilators. Treatment with 10-fold therapeutic dosages of thiabendazole (440 mg/kg) on each of 2 successive days resulted in permanent cessation of the clinical signs. 相似文献
199.
Richard T. Mayer John W. Jermyn M.Danny Burke Russell A. Prough 《Pesticide biochemistry and physiology》1977,7(4):349-354
Methoxy-, ethoxy-, propoxy-, and butoxyresorufin were prepared and tested as substrates for the fluorometric assay of O-dealkylation by the mixed-function oxidase system in house flies, Musca domestica L. Methoxyresorufin proved to be the most suitable substrate because of the favorable reaction rates. This sensitive assay can be performed with a minimum of microsomal protein (<0.3 mg/ml) in 5 min or less. The apparent Km and maximum velocity were calculated as 2.88 μM and 0.27 nmol of resorufin produced/min/mg of microsomal protein, respectively. The O-dealkylation reaction required O2 and NADPH and was inhibited by CO. 相似文献
200.
S. McDougall C. R. Burke K. L. Macmillan N. B. Williamson 《Research in veterinary science》1995,58(3)
The ovaries of 17 Friesian cows aged two to seven years were examined daily by transrectal ultrasound from one week after calving. The position and size of all follicles more than 2 mm in diameter were recorded. A large (more than 9 mm in diameter) follicle was present on at least one ovary by six to 17 days after calving, and in two of the cows it ovulated; the remaining cows had from two to nine large follicles before they ovulated. The mean (
) interval from calving to the first ovulation was 43 ·4 (5·3) (range 13 to 93) days, after 4·2 (0·6) waves of follicles. 相似文献