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921.
Matthews H Granger N Wood J Skelly B 《Veterinary journal (London, England : 1997)》2012,191(3):396-398
The effects of essential fatty acid supplementation (EFA) on the control of idiopathic epilepsy in dogs were investigated in a blinded, placebo-controlled trial. Fifteen dogs were treated with triple purified Ω-3 oil containing 400 mg eicosapentaenoic acid, 250 mg docosahexaenoic acid and 22 mg vitamin E per 1.5 mL at a dose of 1.5 mL/10 kg once daily for 12 weeks, followed by a 12 week placebo period of supplementation with olive oil. Owners recorded seizure frequency and severity and any adverse events. EFA supplementation did not reduce seizure frequency or severity in dogs with idiopathic epilepsy. 相似文献
922.
A retrospective study assessing treatment-related toxicities in tumor-bearing cats treated with temozolomide (TMZ) alone or in combination with doxorubicin was conducted. TMZ was administered orally once a day for 5 days every 3 weeks at a dose of 20 mg/cat. Tumor response was evaluated with standard World Health Organization criteria and toxicity was monitored using veterinary co-operative oncology group-common terminology criteria for adverse events (VCOG--CTCAE) criteria. Ten tumor-bearing cats with various types of malignancies were treated with TMZ-based chemotherapy. Eight cats were evaluable for response. Two cats achieved a complete response, one achieved stable disease and five achieved a partial response. Four grade III and one grade IV hematological toxicities, and one grade IV gastrointestinal toxicity were observed. Four cats were euthanased as a result of apparent toxicity. One cat was euthanased as a result of severe and prolonged myelosuppression with fever. Three were euthanased for grade III pleural and pericardial effusions. Effusion was seen in cats treated with higher cumulative dose of TMZ (P = 0.0046). Planned additional case accrual was discontinued because of unacceptable levels of toxicity despite evidence of efficacy in some of the cats. Additional investigation is needed to elucidate this unexpected apparent cumulative toxicity. 相似文献
923.
Yaling Zhang Carl Menke Barbara Drigo Shahla Hosseini Bai Ian Anderson Zhihong Xu Hong Chen Manyun Zhang 《Journal of Soils and Sediments》2017,17(10):2410-2419
Purpose
Re-establishment of soil nitrogen (N) capital is a priority in mine rehabilitation. We aimed to evaluate the effects of biochar addition on improving mine spoil N pools and the influence of elevated CO2 concentration on mine rehabilitation.Materials and methods
We assessed the effects of pinewood biochar, produced at three temperatures (650, 750 and 850 °C, referred as B650, B750 and B850, respectively), on mine spoil total N concentrations with five different plant species, including a tree species (Eucalyptus crebra), N-fixing shrubs (Acacia floribunda and Allocasuarina littoralis) and C3 and C4 grasses (Austrodanthonia tenuior and Themeda australis) incubated at ambient (400 μL L?1) and elevated (700 μL L?1) atmospheric CO2 concentrations, as well as the effects of elevated CO2 on mine rehabilitation.Results and discussion
Soil total N significantly improved following biochar incorporation under all plant species (P < 0.05) except for T. Australis. E. crebra had the highest soil total N (0.197%, 0.198% and 0.212% for B650, B750 and B850, respectively). Different from the negligible influence of elevated CO2 on soil properties under the grasses and the N-fixing shrubs, elevated CO2 significantly increased soil water and hot water extractable organic C (WEOC and HWEOC, respectively) and decreased total C under E. crebra, indicating that the nutrient demands were not met.Conclusions
Biochar addition showed the potential in mine rehabilitation in terms of improving soil N pool, especially with E. crebra. However, it would be more difficulty to rehabilitate mine spoils in future with the rising atmospheric CO2 concentration.924.
925.
926.
Jamal El Khattabi Barbara Louche Hanan Darwishe Fadi Chaaban Erick Carlier 《Water, air, and soil pollution》2018,229(4):128
In France, the quality of water resources with respect to nitrates deteriorated between the beginning of 1970s and 2000s. A stabilization of the situation and of the improvements has been observed punctually since the 2000s. Despite the application of the Nitrates Directive in France (91/676/CEE), the overall situation remains degraded, with numerous increases in nitrate concentrations in the underground waters. In the North of France, an alluvial groundwater’s nitrate concentration exceeds the drinking water limit fixed at 50 mg/l, in the sectors of Catillon-sur-Sambre and Rejet-de-Beaulieu. In order to quantify and model the impact of agricultural nitrogen on groundwater, an approach based on an integrated model has been established using three specific codes for each lithological horizon: Agriflux (for the root zone), VS2DT (for the unsaturated zone), and ModFlow-MT3D (for the saturated zone). The results illustrate the sensitivity of quality to agricultural crops used. Based on scenarios over 20 years, the predictions show a link between nitrate concentrations in the groundwater and agricultural crops as well as fertilization. Improving quality with a concentration of nitrate less than 50 mg/l requires a reasoned management accompanied by rotations of crops and transformations into grasslands and for sensitive areas the use of the culture producing the least nitrogen flow such as beets. The integrated model constitutes an efficient tool for predicting the evolution of the groundwater quality, especially in sensitive areas like the valleys with a rapid nitrate transfer to the aquifer. The model makes it possible to correctly evaluate the concentrations of nitrates reaching the groundwater with a monitoring of the concentration evolution in each lithological horizon, thus constituting a good tool for the management of agricultural pollution. 相似文献
927.
Tanya Duke-Novakovski Barbara Ambros Cindy Feng Anthony P. Carr 《Veterinary anaesthesia and analgesia》2017,44(3):589-593
Objective
To determine the accuracy of high-definition oscillometry (HDO) for arterial pressure measurement during injectable or inhalation anesthesia in horses.Study design
Prospective, clinical study.Animals
Twenty-four horses anesthetized for procedures requiring lateral recumbency.Methods
Horses were premedicated with xylazine, and anesthesia induced with diazepam–ketamine. Anesthesia was maintained with xylazine–ketamine–guaifenesin combination [TripleDrip (TD; n = 12) or isoflurane (ISO; n = 12)]. HDO was used to obtain systolic (SAP), mean (MAP) and diastolic (DAP) arterial pressures, and heart rate (HR) using an 8-cm-wide cuff around the proximal tail. Invasive blood pressure (IBP), SAP, MAP, DAP and HR were recorded during HDO cycling. Bland–Altman analysis for repeated measures was used to compare HDO and IBP for all measurements. The generalized additive model was used to determine if means in the differences between HDO and IBP were similar between anesthetic protocols for all measurements.Results
There were >110 paired samples for each variable. There was no effect of anesthetic choice on HDO performance, but more variability was present in TD compared with ISO. Skewed data required log-transformation for statistical comparison. Using raw data and standard Bland–Altman analysis, HDO overestimated SAP (TD, 3.8 ± 28.3 mmHg; ISO, 3.5 ± 13.6 mmHg), MAP (TD, 4.0 ± 23.3 mmHg; ISO, 6.3 ± 10.0 mmHg) and DAP (TD, 4.0 ± 21.2 mmHg; ISO, 7.8 ± 13.6 mmHg). In TD, 26–40% HDO measurements were within 10 mmHg of IBP, compared with 60–74% in ISO. Differences between HDO and IBP for all measurements were similar between anesthetic protocols. The numerical difference between IBP and HDO measurements for SAP, MAP and DAP significantly decreased as cuff width:tail girth ratio increased toward 40%.Conclusion and clinical relevance
More variability in HDO occurred during TD. The cuff width:tail girth ratio is important for accuracy of HDO. 相似文献928.
Aline M. Ambrosio Tatiana P.A. Carvalho-Kamakura Keila K. Ida Barbara Varela Felipe S.R.M. Andrade Lara L. Facó Denise T. Fantoni 《Veterinary anaesthesia and analgesia》2017,44(2):254-263
Objective
To examine the intrapulmonary gas distribution of low and high tidal volumes (VT) and to investigate whether this is altered by an alveolar recruitment maneuver (ARM) and 5 cmH2O positive end-expiratory pressure (PEEP) during anesthesia.Study design
Prospective randomized clinical study.Animals
Fourteen client-owned bitches weighing 26 ± 7 kg undergoing elective ovariohysterectomy.Methods
Isoflurane-anesthetized dogs in dorsal recumbency were ventilated with 0 cmH2O PEEP and pressure-controlled ventilation by adjusting the peak inspiratory pressure (PIP) to achieve a low (7 mL kg?1; n = 7) or a high (12 mL kg?1; n = 7) VT. Ninety minutes after induction (T90), an ARM (PIP 20 cmH2O for 10 seconds, twice with a 10 second interval) was performed followed by the application of 5 cmH2O PEEP for 35 minutes (RM35). The vertical (ventral=0%; dorsal=100%) and horizontal (right=0%; left=100%) center of ventilation (CoV), four regions of interest (ROI) (ventral, central-ventral, central-dorsal, dorsal) identified in electrical impedance tomography images, and cardiopulmonary data were analyzed using two-way repeated measures anova.Results
The low VT was centered in more ventral (nondependent) areas compared with high VT at T90 (CoV: 38.8 ± 2.5% versus 44.6 ± 7.2%; p = 0.0325). The ARM and PEEP shifted the CoV towards dorsal (dependent) areas only during high VT (50.5 ± 7.9% versus 41.1 ± 2.8% during low VT, p = 0.0108), which was more distributed to the central-dorsal ROI compared with low VT (p = 0.0046). The horizontal CoV was centrally distributed and cardiovascular variables remained unchanged throughout regardless of the VT, ARM, and PEEP.Conclusions and clinical relevance
Both low and high VT were poorly distributed to dorsal dependent regions, where ventilation was improved following the current ARM and PEEP only during high VT. Studies on the role of high VT on pulmonary complications are required. 相似文献929.
Chutsuda Junsopa Sanun Jogloy Weerasak Saksirirat Patcharin Songsri Thawan Kesmala Barbara B. Shew 《European journal of plant pathology / European Foundation for Plant Pathology》2018,151(1):251-255
Stem rot caused by Sclerotium rolfsii is an important problem for Jerusalem artichoke production. Host plant resistance is the most promising method to control disease. If resistant genotypes can be identified in seedlings and this resistance is closely related to resistance at maturity, the evaluation of disease resistance in adult plants could be curtailed or omitted, increasing the speed and efficiency of screening. The objective of this study was to determine the relationship between resistance to S. rolfsii in Jerusalem artichoke in seedling and in adult stages under field conditions. Field experiments were set up in different soil fertility environments in the rainy season during July to October 2014. In each environment, 10 varieties of Jerusalem artichoke with differences in resistance to S. rolfsii were planted and inoculated either 15 or 45 days after transplanting. Higher disease incidence was observed on adult plant stage, but disease severity was similar for both plant stages. The correlations between seedling and adult responses were positive and significant for disease incidence, area under disease progress curve and severity index. Screening for resistance to S. rolfsii in Jerusalem artichoke can be carried out on seedlings, thus improving the efficiency of selection. 相似文献
930.
Lahoz Ernesto Tarantino Paola Mormile Pasquale Malinconico Mario Immirzi Barbara Cermola Michele Carrieri Raffaele 《植物病害和植物保护杂志》2018,125(3):287-296
Journal of Plant Diseases and Protection - Two field trials in integrated cultivation (2014 and 2016) were carried out with the aim to evaluate the efficacy and the persistence of copper... 相似文献