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91.
Hans D. Westermeyer Daniel A. Ward Jacqueline C. Whittemore Jeremiah A. Lyons 《Veterinary ophthalmology》2013,16(6):459-463
An 8‐year‐old, brachycephalic, mixed breed cat underwent full mouth tooth extractions for the treatment of tooth root abscessation. Subsequently, the cat developed anterior uveitis refractory to topical therapy that eventually necessitated enucleation. Actinomyces species were isolated from both the tooth root abscesses and the anterior chamber after enucleation. Histopathology of the enucleated eye revealed panophthalmitis with abundant intralesional bacteria morphologically consistent with Actinomyces. Between the time of tooth root extraction and enucleation (20 weeks), the cat was diagnosed with hyperthyroidism and treated with oral steroids for inflammatory bowel syndrome. We believe this report represents a rare case of endogenous endophthalmitis secondary to dental disease, possibly precipitated by concurrent immunosuppression. 相似文献
92.
AS Watts 《New Zealand veterinary journal》2013,61(2):111-114
Abstract CASE HISTORY: A 10-year-old Friesian dairy cow presented with a history of weight loss, decreased milk production and fluid splashing on auscultation of the heart. Previous antibiotic therapy included oxytetracycline, marbofloxacin and penicillin. CLINICAL AND PATHOLOGICAL FINDINGS: Following a failure to respond to treatment, prescribed by the referring veterinarian for respiratory infection and septic arthritis, the cow was referred to Massey University Veterinary Teaching Hospital with suspected pericarditis. Clinical examination identified a predominantly left sided holodiastolic heart murmur with tachycardia and cording of the jugular veins. Cardiac ultrasound showed an enlarged aortic valve with turbulent blood flow and regurgitation, consistent with bacterial endocarditis. Blood culture demonstrated Paenibacillus spp. Due to the severity of the clinical signs and poor prognosis, euthanasia was performed and a post-mortem examination carried out. DIAGNOSIS: Traumatic reticuloperitonitis with abscessation of the reticulum and rumen wall, which progressed to a bacteraemia and presumptively caused endocarditis, endometritis, septic arthritis, and renal and myocardial infarcts due to emboli from the endocarditis lesions. CLINICAL RELEVANCE: New Zealand dairy cattle are at risk of traumatic reticuloperitonitis and due to varying presentations diagnosis can be complicated. Subsequent bacteraemia is common and in this case the novel bacterial species Paenibacillus was implicated as a potential pathogen. 相似文献
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Effect of Manuka honey gel on the transforming growth factor β1 and β3 concentrations,bacterial counts and histomorphology of contaminated full‐thickness skin wounds in equine distal limbs
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95.
J.C. Whittemore J.R. Hawley W.A. Jensen M.R. Lappin 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2010,24(2):306-313
Background: Cats inoculated with feline herpesvirus 1, calicivirus, and panleukopenia (FVRCP) vaccines grown on the Crandell Rees feline kidney (CRFK) cell line have been shown to develop anti‐CRFK antibodies. The identities of common CRFK antigens are unknown. Hypothesis: Cats inoculated with CRFK lysates and FVRCP vaccines will develop autoantibodies measurable by Western blot immunoassay. Antigens associated with these antibodies can be isolated for further study. Animals: One CRFK hyperinoculated rabbit, 44 age‐matched unvaccinated kittens purchased from a commercial vendor. Methods: Commonly recognized CRFK antigens were identified by comparison of Western blot immunoassays using sera from a hyperinoculated rabbit and kittens inoculated with CRFK lysate or 1 of 4 commercially available FVRCP vaccines. Antigens were purified from CRFK lysates and sequenced. Antigen recognition was confirmed by Western blot immunoassay and indirect ELISA for 2 proteins using sera from CRFK and FVRCP inoculated kittens. Results: CRFK antigens 47, 40, and 38 kD in size were identified. Protein isolation and sequencing identified 3 CRFK proteins as α‐enolase, annexin A2, and macrophage capping protein (MCP). Sera from FVRCP and CRFK inoculated cats were confirmed to recognize annexin A2 and α‐enolase by Western blot immunoassay and indirect ELISA. Conclusions and Clinical Relevance: This study validated the use of Western blot immunoassay for detection of antibodies against CRFK proteins and identified 3 CRFK antigens. In humans, α‐enolase antibodies are nephritogenic; α‐enolase and annexin A2 antibodies have been associated with autoimmune diseases. Further research will be necessary to determine the clinical relevance of these findings. 相似文献
96.
I. FRANCISCO J. A. SÁNCHEZ F. J. CORTIÑAS R. FRANCISCO E. MOCHALES M. ARIAS P. MULA J. L. SUÁREZ P. MORRONDO P. DÍEZ‐BAÑOS R. SÁNCHEZ‐ANDRADE A. PAZ‐SILVA 《Equine veterinary journal》2009,41(7):713-715
The aim of this study was to assess, by a clinical trial, the efficacy of an ivermectin‐based pour‐on treatment against gastrointestinal parasitic nematodes in naturally infected horses using 2 groups of mature indigenous Pura Raza Galega grazing mares. Faecal and blood samples were collected individually over a 21 week period. Faeces were analysed by the coprological flotation, sedimentation and migration techniques. Changes in circulating blood cells were monitored over the study period. The administration of the ivermectin suppressed the eggelimination of ascarids and pinworms throughout the study and no strongyle‐eggs were observed in the treatment group between the 3rd and 10th weeks. The numbers of red cells increased significantly after the anthelmintic therapy, and a statistical reduction in circulating leucocytes was recorded. No side effects were observed. The pour‐on ivermectin formulation was highly successful against gastrointestinal nematodes and appears to be a useful therapeutic routine for large groups of horses. 相似文献
97.
In this study, the effects of aqueous extracts from Zygophyllum fabago L. on two plant phytopathogenic fungal species (namely, Fusarium oxyosporum f. sp. melonis and Pythium aphanidermatum) were studied under laboratory conditions. The plant extracts (10% w/v) were prepared by using deionized water and fresh tissues. Dilutions (2, 4, 6, and 8% w/v) were obtained to test their effect on the mycelial growth of the phytopathogenic species. Additionally, the recovery of the fungi after their exposure to the Z. fabago extract was analyzed. The plant extracts inhibited the growth of F. oxyosporum and P. aphanidermatum (the maximum mean inhibition that was recorded with the 10% w/v extracts was 42.9% and 85.3%, respectively). A second series of experiments demonstrated the existence of residual effects in both species. The amount of residual inhibition by the 10% w/v extracts was 28.6% in F. oxyosporum and 53.8% in P. aphanidermatum. A dose–response was clearly observed in P. aphanidermatum, while an increase in extract concentration was not associated with a significantly greater reduction in the growth of F. oxyosporum. These findings give insights into the potential of Z. fabago as a growth inhibitor of F. oxyosporum and P. aphanidermatum, thus suggesting an interesting potential role for this common weed as a source of natural fungicides. 相似文献
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