( 3 H)lysergic acid diethylamide: cellular autoradiographic localization in rat brain

Intravenous administration of [(3)H]lysergic acid diethylamide(LSD) to rats resulted in accumulation of the drug in the brain within 15 minutes. Autoradiographic methods were used to differentiate free and bound [(3)H]LSD in brain tissue.Free [(3)H]LSD was generally distributed in the pituitary and pineal glands, cerebellum, hippocampus,and choroid plexus.Bound [(3)H]LSD was localized in neurons of the cortex, caudate nucleus, midbrain, and medulla,as well as in choroid plexus epithelium.     

Double-labeled metabolic maps of memory

The physical changes representing a memory are believed to be localized to specific neurons, widely distributed in multiple parallel pathways in the brain. 2-Fluorodeoxyglucose, labeled with two discriminable radioactive tracers, was used to construct quantitative metabolic maps in split-brain cats during a visual task. One side of the brain served to estimate the metabolic variability of nonspecific influences. The other side was used to map metabolic changes related to the presence of previously learned visual cues, as well as changes related to nonspecific influences, in the same periods of time. When the two sides were compared, between 5 million and 100 million neurons (depending upon the significance level selected) were identified in which activity increased during presentation of the familiar cues. The wide distribution of these neurons throughout the brain is compatible with prior evidence of a distributed memory system. However, the large number of neurons involved is difficult to reconcile with theories in which individual neurons are dedicated to specific memories.     

Highly polarized photoluminescence and photodetection from single indium phosphide nanowires

We have characterized the fundamental photoluminescence (PL) properties of individual, isolated indium phosphide (InP) nanowires to define their potential for optoelectronics. Polarization-sensitive measurements reveal a striking anisotropy in the PL intensity recorded parallel and perpendicular to the long axis of a nanowire. The order-of-magnitude polarization anisotropy was quantitatively explained in terms of the large dielectric contrast between these free-standing nanowires and surrounding environment, as opposed to quantum confinement effects. This intrinsic anisotropy was used to create polarization-sensitive nanoscale photodetectors that may prove useful in integrated photonic circuits, optical switches and interconnects, near-field imaging, and high-resolution detectors.     

Hierarchical self-assembly of F-actin and cationic lipid complexes: stacked three-layer tubule networks

We describe a distinct type of spontaneous hierarchical self-assembly of cytoskeletal filamentous actin (F-actin), a highly charged polyelectrolyte, and cationic lipid membranes. On the mesoscopic length scale, confocal microscopy reveals ribbonlike tubule structures that connect to form a network of tubules on the macroscopic scale (more than 100 micrometers). Within the tubules, on the 0.5- to 50-nanometer length scale, x-ray diffraction reveals an unusual structure consisting of osmotically swollen stacks of composite membranes with no direct analog in simple amphiphilic systems. The composite membrane is composed of three layers, a lipid bilayer sandwiched between two layers of actin, and is reminiscent of multilayered bacterial cell walls that exist far from equilibrium. Electron microscopy reveals that the actin layer consists of laterally locked F-actin filaments forming an anisotropic two-dimensional tethered crystal that appears to be the origin of the tubule formation.     

商标权价格评估探析

商标权价格评估是资产评估的重要内容。分析了商标权价值形成的因素及商标权价格评估的基础,确立了商标权价格评估的原则,概括了商标权评估的范围,阐述了商标权价格评估的基本方法,探讨了商标权价格评估应注意的问题。     

国槐、剌槐幼苗根系固氮酶活性的研究

研究了刺槐(Robinia pseudoacacia)、国槐(Sophora japonica)一年生幼苗根系固氮酶活性的季节性变化,并且通过植物离体根尖接种根瘤菌试验和分析植物根系分泌物反映了国槐、刺槐根系固氮的某些特性。     

立式浮放储罐三维地震动台模型试验分析

为分析立式浮放储罐在三维地震动作用下的结构反应,进行了1000m3储罐模型地震动模拟试验,通过输入水平、竖向、三维地震激励,测试立式浮放储罐的地震响应。结果表明:储罐在三维地震动激励下的地震反应与一维激励相比具有较明显的放大效应。加速度反应放大1.76%~79.08%,平均放大幅度42.86%;三维激励下位移主要表现为放大趋势,平均放大幅度为31.83%;三维激励条件下储罐发生提离的概率及提离高度明显增大,增幅在20.47%~79.54%。建议立式浮放储罐应考虑三维地震动进行地震反应分析。     

糯玉米杂交种主要经济性状及品质因素研究

利用2001年、2002年、2004年山东省特种玉米区域试验汇总资料,通过对参试糯玉米品种株型、鲜穗采收期、产量性状、商品果穗率、品质性状、抗病性等指标进行综合分析,为指导山东省糯玉米育种提供借鉴和参考。研究结果表明:目前山东省糯玉米品种紧凑型株型偏少;鲜穗采收期存在较大差异;参试品种的产量和穗粒数差异显著;一些参试品种的双穗率过高,影响商品果穗率偏低;参试品种蛋白质、游离氨基酸、赖氨酸、可溶性糖的含量差异都很显著,风味品质分差异不明显;参试品种对茎腐病、大斑病、弯孢菌叶斑病的抗性较差。     

Prostaglandins stimulate thyroid function in pregnant women

Intravaginal or intravenous administration of prostaglandin F(2alpha) to pregnant women produced significant elevations of plasma triiodothyronine and thyroxine concentrations, but no rise of thyrotropin. These observations are consistent with those of previous in vitro studies indicating that prostaglandins can act directly on the thyroid gland to stimulate thyroid hormone synthesis or release, or both.     

蛋白PAGE法鉴定玉米近缘自交系的初步研究

以种子蛋白图谱为指标，分析了由系谱法、回交法所选育的一套遗传梯度不同的玉米自交系和姊妹系的差异。结果表明，用ＰＡＧＥ法所测定的种子蛋白谱带能鉴别出遗传成分差异在１３％以上的两个自交系及自交后代材料的纯合程度的遗传稳定性，可以作为玉米自交系选育的一个辅助指标。