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排序方式: 共有537条查询结果,搜索用时 31 毫秒
441.
MG Stevens B De Spiegeleer L Peelman XJ Boulougouris AV Capuco C Burvenich 《Veterinary immunology and immunopathology》2012,149(3-4):151-156
During early lactation, dairy cow are prone to developing severe mastitis in responses to intramammary Escherichia coli infections. These severe inflammatory responses have been correlated with reduced neutrophil function during the periparturient period. However, the causative mechanism of neutrophil dysfunction has not been elucidated. Studies in murine sepsis models have shown that during sepsis neutrophils are functionally paralysed due to the presence of high concentrations of complement factor 5a (C5a). In this review, we hypothesize that C5a as a critical early mediator in the development of severe E. coli mastitis. Furthermore, preliminary data suggest that crosstalk between C5a and TLR4 signalling in neutrophils may provide a positive feedback mechanism that may be involved in the pathogenesis of a severe mastitis response. Finally, we focus on the therapeutic potential of disrupting the C5a signalling pathway as an important strategy for treatment of severe E. coli mastitis in dairy cattle. 相似文献
442.
Jon S. West James A. Townsend Mark Stevens Bruce D. L. Fitt 《European journal of plant pathology / European Foundation for Plant Pathology》2012,133(1):315-331
This review describes environmental factors that influence severity of crop disease epidemics, especially in the UK and north-west
Europe, in order to assess the effects of climate change on crop growth and yield and severity of disease epidemics. While
work on some diseases, such as phoma stem canker of oilseed rape and fusarium ear blight of wheat, that combine crop growth,
disease development and climate change models is described in detail, climate-change projections and predictions of the resulting
biotic responses to them are complex to predict and detailed models linking climate, crop growth and disease development are
not available for many crop-pathogen systems. This review uses a novel approach of comparing pathogen biology according to
‘ecotype’ (a categorization based on aspects such as epidemic type, dissemination method and infection biology), guided by
detailed disease progress models where available to identify potential future research priorities for disease control. Consequences
of projected climate change are assessed for factors driving elements of disease cycles of fungal pathogens (nine important
pathogens are assessed in detail), viruses, bacteria and phytoplasmas. Other diseases classified according to ‘ecotypes’ were
reviewed and likely changes in their severity used to guide comparable diseases about which less information is available.
Both direct and indirect effects of climate change are discussed, with an emphasis on examples from the UK, and considered
in the context of other factors that influence diseases and particularly emergence of new diseases, such as changes to farm
practices and introductions of exotic material and effects of other environment changes such as elevated CO2. Good crop disease control will contribute to climate change mitigation by decreasing greenhouse gas emissions from agriculture
while sustaining production. Strategies for adaptation to climate change are needed to maintain disease control and crop yields
in north-west Europe. 相似文献
443.
444.
Abstract Malathion seed treatments were evaluated as a means of protecting aerially‐sown rice from attack by Chironomus tepperi Skuse and other chironomids in New South Wales, Australia. Four treatments were examined: malathion applied to seed at 150, 300, and 450 ga.i/ha, and malathion applied directly to water at 300 ga.i./ha. Chironominae were significantly suppressed for 10 days by all treatments, but populations were often significantly above control levels at 20 and 25 days post‐treatment. None of the treatments significantly reduced other chironomids(predominantly Tanypodinae) at any stage of the trial. Emergence trap data from control and water treatment bays showed that there was, in practical terms, only a single generation of C. tepperi during crop establishment, and that malathion applied directly to water at 300 ga.i./ha almost completely eliminated adult emergence in this species. Bioassays of field‐collected water samples showed that malathion dissipates readily from seed into the water column. Toxicity profiles over time for the 150 and 300 g a.i./ha seed treatments were statistically similar to that for the 300 ga.i./ha water treatment. Although the 450 ga.i./ha seed treatment provided slightly longer residual toxicity, control was not enhanced sufficiently to justify an increase in the existing application rate of 300 ga.i./ha. 相似文献
445.
S. Hughes D. A. Norris P. A. Stevens B. Reynolds T. G. Williams C. Woods 《Water, air, and soil pollution》1994,77(1-2):115-139
The influence of forest development on soil solution and surface drainage water aluminium chemistry was investigated in Sitka spruce (Picea sitchensis) plantations in Wales. Comparisons with semi-natural grassland and moorland sites are described. A highly significant positive relationship was shown between increasing forest age and soilwater aluminium concentrations in the B horizons. Shortterm/episodic peaks in Al concentrations were strongly related to incidences of high concentrations of neutral, marine-derived, salts in the soilwater. Nitrification may be an important factor in soil acidification and the mobilization of Al in soilwaters beneath the older mature-forest plantations in Wales. Labile monomeric Al concentrations were largest in surface waters draining the oldest forestry plantations compared with younger forest catchments and moorland, although response to discharge of soilwater acidity to the surface waters at individual sites was dependent on the acid neutralizing capacity of the groundwater component of the surface waters. 相似文献
446.
A new 15N tracing model was developed to analyse nitrogen (N) transformations in old grassland soil. There was a need to develop a new model because existing models such as FLUAZ were not able to simulate the observed N dynamics. The new features of the model are: (a) simulation of heterotrophic nitrification, (b) simulation of dissimilatory nitrate (NO3−) reduction to ammonium (NH4+) (DNRA), (c) release of adsorbed or stored fertiliser N into the available mineral N pools and (d) immobilisation of NH4+ and NO3− into two separate organic N pools with different re-mineralisation characteristics. The tracing model contains six N pools and nine simultaneous N transformations either at zero- or first-order kinetics. The model is set up in the modelling software ModelMaker which contains non-linear optimisation routines based on the Marquardt-Levenberg algorithm. The model is able to simulate data obtained from triple labelling studies where either the NH4+, the NO3− or both pools were labelled with 15N. The flexible modelling environment allows the user to develop the model further. 相似文献
447.
448.
Gosling A Stevens GW Barber AR Kentish SE Gras SL 《Journal of agricultural and food chemistry》2011,59(7):3366-3372
Prebiotic galactosyl oligosaccharides (GOS) are produced from lactose by the enzyme β-galactosidase. It is widely reported that the highest GOS levels are achieved when the initial lactose concentration is as high as possible; however, little evidence has been presented to explain this phenomenon. Using a system composed of the commercial β-galactosidase derived from Bacillus circulans known as Biolacta FN5, lactose and sucrose, the relative contribution of water activity, and substrate availability were assessed. Oligosaccharide levels did not appear to be affected by changes in water activity between 1.0 and 0.77 at a constant lactose concentration. The maximum oligosaccharide concentration increased at higher initial concentrations of lactose and sucrose, while initial reaction rates for transfer increased but remained constant for hydrolysis. This suggests that the high oligosaccharide levels achieved at the raised initial saccharide concentration are due to increases in reactions that form oligosaccharides rather than decreases in concurrent reactions, which degrade oligosaccharides. There were different effects from changing the initial concentration of lactose compared to sucrose, suggesting that the ability of lactose to act as a donor saccharide may be more important for increasing maximum oligosaccharide concentrations than the combined ability of both saccharides to act as galactosyl acceptors. 相似文献
449.
Andrew M. Griffiths Jonathan S. Ellis Darryl Clifton-Dey Gonzalo Machado-Schiaffino Dylan Bright Eva Garcia-Vazquez Jamie R. Stevens 《Biological conservation》2011,144(11):2733-2738
Since the 1970s, when major improvements to the water quality were made, the River Thames has been subject to a high-profile project aimed at restoring Atlantic salmon to the catchment. Whilst initially successful, with hundreds of salmon returning each year in the late 1980s, the number of adults returning to the river has declined steeply again in recent years, reaching a low in 2005 when no salmon were recorded. Using a baseline of genetic information gathered from 3830 salmon from throughout their southern European range, and incorporating samples from the hatchery fish used to stock the Thames, all 10 tagged hatchery fish captured in 2003 and all 16 returning untagged adult salmon captured between 2005 and 2008 were assigned to their most likely river of origin. The results suggest that untagged salmon currently ascending the river originate not from exogenous fish stocked into the Thames, but predominantly from other rivers in southern England. This highlights the potential for natural processes of recolonisation to operate in rivers where salmon have become locally extirpated. These findings also underscore several important considerations when undertaking species restoration projects: (i) previous causes of declines must be sufficiently ameliorated to allow new/translocated individuals to thrive, (ii) introduced individuals should originate from a stock that is closely related to the extirpated population, according to the principles of contemporary conservation biology, and (iii) dispersal and gene-flow from neighbouring populations may play a significant role in establishing new populations. 相似文献
450.
How successful are plant species reintroductions? 总被引:1,自引:0,他引:1
Sandrine Godefroid Carole Piazza Graziano Rossi Stéphane Buord Albert-Dieter Stevens Ruth Aguraiuja Carly Cowell Carl W. Weekley Gerd Vogg José M. Iriondo Isabel Johnson Bob Dixon Doria Gordon Sylvie Magnanon Bertille Valentin Kristina Bjureke Rupert Koopman Magdalena Vicens Myriam Virevaire Thierry Vanderborght 《Biological conservation》2011,(2):672-682
Reintroduction of native species has become increasingly important in conservation worldwide for recovery of rare species and restoration purposes. However, few studies have reported the outcome of reintroduction efforts in plant species. Using data from the literature combined with a questionnaire survey, this paper analyses 249 plant species reintroductions worldwide by assessing the methods used and the results obtained from these reintroduction experiments. The objectives were: (1) to examine how successful plant species reintroductions have been so far in establishing or significantly augmenting viable, self-sustaining populations in nature; (2) to determine the conditions under which we might expect plant species reintroductions to be most successful; (3) to make the results of this survey available for future plant reintroduction trials. Results indicate that survival, flowering and fruiting rates of reintroduced plants are generally quite low (on average 52%, 19% and 16%, respectively). Furthermore, our results show a success rate decline in individual experiments with time. Survival rates reported in the literature are also much higher (78% on average) than those mentioned by survey participants (33% on average). We identified various parameters that positively influence plant reintroduction outcomes, e.g., working in protected sites, using seedlings, increasing the number of reintroduced individuals, mixing material from diverse populations, using transplants from stable source populations, site preparation or management effort and knowledge of the genetic variation of the target species. This study also revealed shortcomings of common experimental designs that greatly limit the interpretation of plant reintroduction studies: (1) insufficient monitoring following reintroduction (usually ceasing after 4 years); (2) inadequate documentation, which is especially acute for reintroductions that are regarded as failures; (3) lack of understanding of the underlying reasons for decline in existing plant populations; (4) overly optimistic evaluation of success based on short-term results; and (5) poorly defined success criteria for reintroduction projects. We therefore conclude that the value of plant reintroductions as a conservation tool could be improved by: (1) an increased focus on species biology; (2) using a higher number of transplants (preferring seedlings rather than seeds); (3) taking better account of seed production and recruitment when assessing the success of reintroductions; (4) a consistent long-term monitoring after reintroduction. 相似文献