A survey of yield differences between transgenic and non-transgenic crops

In the current survey, there was no clear evidence that GM (genetically modified) crops are higher yielding than those conventionally bred<fnoteref rid="fn1">1</fnoteref>. Furthermore, there were no trials to support valid comparisons of yield per se. This article investigates GM crop yields, introducing the importance of hybrid vigour and a non-stress environment for higher percentage heritability selection and therefore more productive conventional plant breeding and improved crops. GM technology and crops are compared with proven plant breeding methods, with respect to hybrid vigour and the economic viability of both systems. These proven methods of plant breeding are (1) traditional landrace cropping, (2) conventional Mendelian breeding and (3) Isolection Mendelian breeding, and are also considered historically.     

A preliminary investigation comparing pre-operative morphine and buprenorphine for postoperative analgesia and sedation in cats

Objective To compare the postoperative analgesic and sedative properties of buprenorphine and morphine in cats. Study Design Prospective, randomized, blinded study. Animals Thirty‐two domestic cats undergoing surgery. Methods Cats received pre‐anaesthetic medication with acepromazine (0.05 mg kg^?1) given intramuscularly and were randomly allocated to group M and given morphine (0.1 mg kg^?1) intramuscularly (IM) or to group B and given buprenorphine (0.01 mg kg^?1) IM. Anaesthesia was induced with propofol and maintained with halothane in oxygen and nitrous oxide. Pain and sedation scores using visual analogue scales, and heart and respiratory rates, were measured immediately before, and 30, 60, 120, 180, 300 and 420 minutes after anaesthesia. Results Pain scores were significantly lower at 60, 120 and 180 minutes after anaesthesia in group B. Group B also had higher heart rates at 30 minutes. There were no other statistically significant differences between the groups. Clinical relevance Buprenorphine (0.01 mg kg^?1) appeared to provide better postoperative analgesia than morphine (0.1 mg kg^?1) and may also have a longer duration of action.     

Effects of rotation, stubble retention and cultivation on take-all and eyespot of wheat in northeastern Victoria, Australia

The effects of different rotations and methods of seed-bed preparation on take-all (Gaeumannomyces graminis var. tritici) (Ggt) and eyespot (Tapesia yallundae; anomorph Pseudocercosporella herpotrichoides) of wheat (Triticum aestivum) were investigated in 1984–1986 in a long-term field experiment (established in 1981), on a fine sandy-clay loam in northeastern Victoria. One treatment, representing the conventional practice, involved burning stubble from the preceding crop followed by four passes with a scarifier in the autumn before sowing wheat each year. Other treatments were direct drilled each year (sown without prior cultivation) and included two stubble treatments (retained or burnt) in either continuously cropped wheat or in lupin (Lupinus angustifolius)-wheat rotations.

High levels of take-all and eyespot developed in the continuously cropped wheat (up to 79% and 66% plants affected, respectively). On the other hand, the incidence of plants with either disease was very low or negligible in wheat that was preceded by lupins. In continuous wheat the incidence of plants with Ggt lesions were up to two times higher in the conventionally cultivated treatment (14% 74% and 79% plants affected in 1984, 1985 and 1986, respectively) than in direct drilled treatment (5%, 36% and 39% plants affected, respectively). Generally, the incidence of plants with Ggt lesions and the severity of root symptoms in direct drilled wheat did not differ significantly between the two stubble treatments.

The incidence of eyespot in direct drilled wheat was exacerbated by the retention of wheat stubble on the uncultivated plots (3%, 46% and 66% plants affected in 1984, 1985, and 1986, respectively) but was reduced by burning the stubble (4%, 19% and 33% plants affected in 1984, 1985, 1986, respectively). However, cultivating soil after burning stubble resulted in more plants with eyespot (14%, 39% and 46% plants affected in 1984, 1985 and 1986, respectively) than did burning stubble alone, and in one year the incidence of affected plants in the cultivated treatment was as high as in wheat direct drilled into stubble. The incidence of eyespot was positively correlated (r=0.85, 0.84 and 0.61 in 1984, 1985 and 1986, respectively) with the incidence of lodged tillers. The incidence of lodging was, generally, highest each year in wheat sown directly into wheat stubble and was reduced by burning wheat stubble or by cropping wheat after lupins.

Wojnowicia graminis was frequently isolated, as was Tapesia yallundae, from eyespot lesions suggesting that perhaps not all symptoms of lodging in Victoria can be attributed to Tapesia yallundae.     

Predatory dinosaur remains from madagascar: implications for the cretaceous biogeography of gondwana

Recent discoveries of fossil vertebrates from the Late Cretaceous of Madagascar include several specimens of a large theropod dinosaur. One specimen includes a nearly complete and exquisitely preserved skull with thickened pneumatic nasals, a median frontal horn, and a dorsal projection on the parietals. The new materials are assigned to the enigmatic theropod group Abelisauridae on the basis of a number of unique features. Fossil remains attributable to abelisaurids are restricted to three Gondwanan landmasses: South America, Madagascar, and the Indian subcontinent. This distribution is consistent with a revised paleogeographic reconstruction that posits prolonged links between these landmasses (via Antarctica), perhaps until late in the Late Cretaceous.     

Physicochemical,Nutritional and In Vitro Antidiabetic Characterisation of Blue Whiting (Micromesistius poutassou) Protein Hydrolysates

Protein hydrolysates from low-value underutilised fish species are potential sources of high-quality dietary protein and health enhancing peptides. Six blue whiting soluble protein hydrolysates (BW-SPH-A_F), generated at industrial scale using different hydrolysis conditions, were assessed in terms of their protein equivalent content, amino acid profile and score and physicochemical properties in addition to their ability to inhibit dipeptidyl peptidase IV (DPP-IV) and stimulate the secretion of insulin from BRIN-BD11 cells. Furthermore, the effect of simulated gastrointestinal digestion (SGID) on the stability of the BW-SPHs and their associated in vitro antidiabetic activity was investigated. The BW-SPHs contained between 70–74% (w/w) protein and all essential and non-essential amino acids. All BW-SPHs mediated DPP-IV inhibitory (IC₅₀: 2.12–2.90 mg protein/mL) and insulin secretory activity (2.5 mg/mL; 4.7 to 6.4-fold increase compared to the basal control (5.6 mM glucose alone)). All BW-SPHs were further hydrolysed during SGID. While the in vitro DPP-IV inhibitory and insulin secretory activity mediated by some BW-SPHs was reduced following SGID, the activity remained high. In general, the insulin secretory activity of the BW-SPHs were 4.5–5.4-fold higher than the basal control following SGID. The BW-SPHs generated herein provide potential for anti-diabetic related functional ingredients, whilst also enhancing environmental and commercial sustainability.     

Clinical diagnosis and treatment of suspected neuropathic pain in three dogs

Three dogs were referred to The Queen's Veterinary School Hospital at University of Cambridge for chronic behavioural or locomotor disorders associated with pain. All three had been unsuccessfully treated with conventional analgesics, including non-steroidal anti-inflammatory drugs, glucocorticoids and opiate agonists, prior to referral, with minimal or no response. They were investigated by neurological examination plus conventional ancillary diagnostic tests and therapeutic drug trials. Ruling out other causes of pain and applying previously well-described criteria, each case was diagnosed as consistent with neuropathic pain, a poorly recognised condition in domestic dogs. Treatment with the tricyclic antidepressant drug, amitriptyline, or the antiepileptic drug, gabapentin, resulted in either a dramatic improvement or full resolution of clinical signs in all cases.