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91.
Münker C Pfänder JA Weyer S Büchl A Kleine T Mezger K 《Science (New York, N.Y.)》2003,301(5629):84-87
It has been assumed that Nb and Ta are not fractionated during differentiation processes on terrestrial planets and that both elements are lithophile. High-precision measurements of Nb/Ta and Zr/Hf reveal that Nb is moderately siderophile at high pressures. Nb/Ta values in the bulk silicate Earth (14.0 +/- 0.3) and the Moon (17.0 +/- 0.8) are below the chondritic ratio of 19.9 +/- 0.6, in contrast to Mars and asteroids. The lunar Nb/Ta constrains the mass fraction of impactor material in the Moon to less than 65%. Moreover, the Moon-forming impact can be linked in time with the final core-mantle equilibration on Earth 4.533 billion years ago. 相似文献
92.
93.
Helmy M. Youssef Ravi Koppolu Thorsten Schnurbusch 《Genetic Resources and Crop Evolution》2012,59(7):1319-1328
Labile-barleys (Hordeum vulgare convar. labile (Schiem.) Mansf.) are found in the highlands of Ethiopia, Eretria and North India-Pakistan districts. They represent a distinct spike form showing row-type alterations even within individual spikes of the same genotypes. Variation at the six-rowed spike 1 (vrs1) locus is sufficient to control barley lateral spikelet fertility, which is also modified by alleles at the intermedium-c (int-c) locus. This study aimed at re-sequencing these two loci to investigate whether labile-barleys have a two-rowed genetic background, resulting in increased lateral spikelet fertility, or show reduced lateral spikelet fertility if they possess a six-rowed genetic background. The Vrs1 re-sequencing results of 221 supposedly labile-barley accessions from Ethiopia revealed 13 accessions with two novel vrs1.a1 haplotypes. Following the current nomenclature of vrs1 haplotypes, the new haplotypes were named as haplotypes 66 and 67. Re-sequencing at the int-c locus showed that 118 of the labile-barleys possessed the previously described Int-c.a allele but only one accession was found having a novel Int-c.a haplotype in the homozygous state (termed Int-c.a haplotype1; Hap_1). Interestingly, 101 labile-barleys carried the Int-c.a allele and Int-c.a haplotype1 simultaneously, suggesting maintained heterozygosity or recent gene duplication at this locus. Only one accession had a two-rowed haplotype (Vrs1.b3, int-c.b1) and one accession possessed the Vrs1.t (deficiens) and Int-c.a alleles (six-rowed). These two accessions were considered as misclassified labile genotypes and not included in further analysis. Thus, these results confirmed that all of the 219 labile accessions studied in this work showed six-rowed alleles at vrs1 but reduced lateral spikelet fertility. This reduction is most likely caused by the recessive labile (lab) locus which we are in the process to characterize further. 相似文献
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95.
Sieber JJ Willig KI Kutzner C Gerding-Reimers C Harke B Donnert G Rammner B Eggeling C Hell SW Grubmüller H Lang T 《Science (New York, N.Y.)》2007,317(5841):1072-1076
Most plasmalemmal proteins organize in submicrometer-sized clusters whose architecture and dynamics are still enigmatic. With syntaxin 1 as an example, we applied a combination of far-field optical nanoscopy, biochemistry, fluorescence recovery after photobleaching (FRAP) analysis, and simulations to show that clustering can be explained by self-organization based on simple physical principles. On average, the syntaxin clusters exhibit a diameter of 50 to 60 nanometers and contain 75 densely crowded syntaxins that dynamically exchange with freely diffusing molecules. Self-association depends on weak homophilic protein-protein interactions. Simulations suggest that clustering immobilizes and conformationally constrains the molecules. Moreover, a balance between self-association and crowding-induced steric repulsions is sufficient to explain both the size and dynamics of syntaxin clusters and likely of many oligomerizing membrane proteins that form supramolecular structures. 相似文献