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11.
Numerical modeling of the orbital evolution of interplanetary dust particles revealed that, over the past 1.2 million years, the rate of accretion of dust by Earth has varied by a factor of 2 to 3. These variations display a 100,000-year periodicity and are anticorrelated with Earth's changing orbital eccentricity. Extraterrestrial helium-3 concentrations in a deep-sea sediment core display a similar periodicity but are 50,000 years out of phase with the predicted variations. Also, because collisions between large bodies in the asteroid belt are inevitable, it is expected that large-amplitude stochastic variations on 10(7)- to 10(8)-year time scales would be superimposed on the 10(5)-year periodic variations. 相似文献
12.
SJ Glaser T Schulte-Herbruggen M Sieveking O Schedletzky NC Nielsen OW Sorensen C Griesinger 《Science (New York, N.Y.)》1998,280(5362):421-424
Experiments in coherent magnetic resonance, microwave, and optical spectroscopy control quantum-mechanical ensembles by guiding them from initial states toward target states by unitary transformation. Often, the coherences detected as signals are represented by a non-Hermitian operator. Hence, spectroscopic experiments, such as those used in nuclear magnetic resonance, correspond to unitary transformations between operators that in general are not Hermitian. A gradient-based systematic procedure for optimizing these transformations is described that finds the largest projection of a transformed initial operator onto the target operator and, thus, the maximum spectroscopic signal. This method can also be used in applied mathematics and control theory. 相似文献
13.
During the last interglacial, Antarctic climate changed before that of the Northern Hemisphere. Large local changes in precession forcing could have produced this pattern if there were a rectified response in sea ice cover. Results from a coupled sea ice-ocean general circulation model supported this hypothesis when it was tested for three intervals around the last interglacial. Such a mechanism may play an important role in contributing to phase offsets between Northern and Southern Hemisphere climate change for other time intervals. 相似文献
14.
Reconstructing past ocean pH-depth profiles 总被引:1,自引:0,他引:1
Measurement of boron isotope compositions in species of planktonic foraminifera that calcified their tests at different depths in the water column are used to reconstruct the pH profile of the upper water column of the tropical ocean. Results for five time windows from the middle Miocene to the late Pleistocene indicate pH-depth profiles similar to that of the modern ocean in this area, which suggests that this method may greatly aid in our understanding of the global carbon cycle. 相似文献
15.
The demography of bovine infections caused by Mycobacterium avium subspecies paratuberculosis (MAP) in Ireland is poorly defined. The objective of this study was to describe the demographics of cattle positive to MAP on faecal culture, based on submissions to the Cork Regional Veterinary Laboratory (Cork RVL) from 1994 to 2006. The study focused on all available faecal samples from adult cattle with non-responsive chronic diarrhoea that were submitted by private veterinary practitioners to Cork RVL for MAP culture. For each MAP-positive by faecal culture animal, data were collated from Cork RVL and Cattle Movement Monitoring Scheme (CMMS) records. Johne's disease (JD) was confirmed in 110 animals from 86 herds by the Cork RVL between 1994 and 2006, with a rate of positive cases between 15% and 18% over last four years of the study. Two breeds (Holstein/Friesian or Limousin) made up 78% of submissions. Movements were assessed for the 57 study animals with available movement information, 90% died within one year of the test and 26% tested positive in the herd they were born into. The study provides preliminary information about movement trends and demographics of animals with MAP positive submissions. Although the study area is restricted, it includes the most intensive (and economically-important) dairy region in Ireland. The demographics of JD infection from the study area are in agreement with international reports. Further work is required to determine demographic trends, incidence and prevalence of JD throughout Ireland. It is hoped this work may contribute to the development of a surveillance strategy for MAP by regional veterinary laboratories. 相似文献
16.
Popescu F Wyder M Gurtner C Frey J Cooke RA Greenhill AR Posthaus H 《Veterinary microbiology》2011,153(1-2):173-177
Clostridium perfringens type C causes fatal necrotizing enteritis in different mammalian hosts, most commonly in newborn piglets. Human cases are rare, but the disease, also called pigbel, was endemic in the Highlands of Papua New Guinea. Lesions in piglets and humans are very similar and characterized by segmental necro-hemorrhagic enteritis in acute cases and fibrino-necrotizing enteritis in subacute cases. Histologically, deep mucosal necrosis accompanied by vascular thrombosis and necrosis was consistently reported in naturally affected pigs and humans. This suggests common pathogenetic mechanisms. Previous in vitro studies using primary porcine aortic endothelial cells suggested that beta-toxin (CPB) induced endothelial damage contributes to the pathogenesis of C. perfringens type C enteritis in pigs. In the present study we investigated toxic effects of CPB on cultured primary human macro- and microvascular endothelial cells. In vitro, these cells were highly sensitive to CPB and reacted with similar cytopathic and cytotoxic effects as porcine endothelial cells. Our results indicate that porcine and human cell culture based in vitro models represent valuable tools to investigate the pathogenesis of this bacterial disease in animals and humans. 相似文献
17.
18.
The effects of vaccination of Merino ewes with an attenuated Australian bluetongue virus serotype 23 at different stages of gestation 总被引:1,自引:0,他引:1
SUMMARY A cell culture attenuated Australian bluetongue virus serotype 23 (BLU23) prototype vaccine was assessed for its effects on pregnant Merino sheep. Seventy-six ewes were vaccinated at 5 different stages of gestation, and the failure to lamb at term was as follows: 35 to 43 days of gestation, 20/36 (56%); 57 to 64 days of gestation, 3/10 (30%); 81 to 88 days of gestation, 3/10 (30%); 109 to 116 days of gestation, 0/10 (0%); 130 to 137 days of gestation, 0/10 (0%). Of 30 ewes vaccinated with a cell culture supernatant fluid control between 35 and 43 days of gestation, 6.7% (2/30) failed to lamb at term. Two ewes vaccinated with BLU23 vaccine between 35 and 43 days of gestation had lambs with hydranencephaly. All other lambs born were clinically normal. Three ewes vaccinated with BLU23 aborted. Two of these were vaccinated between 35 and 43 days of gestation, the 3rd between 81 and 88 days of gestation. Five lambs were born with BLU group antibody. Four of these were from ewes vaccinated between 35 and 43 days of gestation, and 2 of these had hydranencephaly. The fifth was from a ewe vaccinated between 57 and 64 days of gestation. The vaccine did not produce disease in adult sheep, but was a potent cause of early foetal death and to a much lesser extent foetal malformation. 相似文献
19.
Forty seven free-ranging, adult, male koalas were captured and administered an intramuscular injection of the dissociative anaesthetic, Telazol (tiletamine HCl plus zolazepam HCl), at dose rates of 5.0 to 7.7 mg/kg body weight. Anaesthesia induction was rapid and smooth and resulted in a surgical plane of anaesthesia lasting 30 to 45 min. There was no depression of heart rate or respiration. Mild salivation occurred in most animals, but was not a problem because the swallowing reflex was retained. There was no mortality or morbidity and the anaesthesia level was sufficient to allow electroejaculation and multiple blood sampling with no apparent animal discomfort. For 10 of 19 males in which anaesthesia was required for a 90 min protocol, a supplementary Telazol injection (average, 2.5 mg/kg) was necessary. All koalas recovered completely within 3 to 4 h of the initial injection. The results suggest that the optimal Telazol dosage for the adult male koala is 7.0 mg/kg body weight. The retrospective analysis of 259 anaesthesia records involving 14 species indicated that Telazol was equally effective and safe in other captive marsupials. 相似文献
20.
Magnetic Field and Plasma Observations at Mars: Initial Results of the Mars Global Surveyor Mission 总被引:2,自引:0,他引:2
MH Acu?a JEP Connerney P Wasilewski RP Lin KA Anderson CW Carlson J McFadden DW Curtis D Mitchell H Reme C Mazelle JA Sauvaud C d'Uston A Cros JL Medale SJ Bauer P Cloutier M Mayhew D Winterhalter NF Ness 《Science (New York, N.Y.)》1998,279(5357):1676-1680
The magnetometer and electron reflectometer investigation (MAG/ER) on the Mars Global Surveyor spacecraft has obtained magnetic field and plasma observations throughout the near-Mars environment, from beyond the influence of Mars to just above the surface (at an altitude of approximately 100 kilometers). The solar wind interaction with Mars is in many ways similar to that at Venus and at an active comet, that is, primarily an ionospheric-atmospheric interaction. No significant planetary magnetic field of global scale has been detected to date (<2 x 10(21) Gauss-cubic centimeter), but here the discovery of multiple magnetic anomalies of small spatial scale in the crust of Mars is reported. 相似文献