Serous cystadenoma in a normally cyclic mare with high plasma testosterone values

Serous cystadenoma was diagnosed by histologic examination of a large ovary removed from a 16-year-old Thoroughbred mare with normal estrous cycles. Palpation and ultrasound examination per rectum had revealed an excessive number of follicles in the right ovary. The ovulation fossa was palpable on the right ovary, and the left ovary appeared to have normal activity. Plasma testosterone values were high at the time of examination (0.15 ng/ml), but decreased to normal values (0.09 ng/ml) after removal of the cystadenoma.     

Use of dynamic compression plates for treatment of tibial diaphyseal fractures in foals: nine cases (1980-1987)

The medical records of 9 foals less than 4 months old, with fracture of the tibial diaphysis, were reviewed. Open reduction was accomplished by use of 3 approaches; however, a cranial approach was preferred and was used in 7 foals. Two dynamic compression plates were implanted in all foals except the first of this series. The technique of plate luting was used in 7 foals and appeared to improve the ability of implants to resist failure. Complications after surgery included partial or complete failure of fracture fixation (n = 3 foals), osteomyelitis (n = 2 foals), angular limb deformity (n = 2 foals), minor dehiscence of the surgical wound (n = 3 foals), and mild extensor deficits of the injured limb (n = 4 foals). One foal was euthanatized 12 hours after surgery because of complete loss of fracture fixation. All other foals were discharged 10 to 295 days after surgery. One or both plates were subsequently removed in 7 foals. Follow-up information was obtained 6 to 36 months after discharge. Excellent results were reported for 6 foals, and good or fair results were reported for the remaining 2 foals.     

Experimental infection of dogs with Brucella abortus: effect of exposure dose on serologic responses and comparison of culture methods

Two studies of experimentally induced Brucella abortus infections in dogs are reported. Twenty dogs in experiment 1 were fed approximately 4.8 X 10(10) colony forming units of B. abortus strain 2308 (BA 2308), and 11 dogs in experiment 2 were fed approximately 3.4 X 10(14) BA 2308. Serum samples from each infected dog and noninfected control were tested on the day of infection and at weekly and biweekly intervals post-infection (PI) for antibodies to B. abortus. The standard tube agglutination (STA) and rivanol (RIV) mean log-titers of the infected dogs in the 2 experiments were compared statistically on the day of infection and on PI days 7, 14, 21, 35, 42 and 49. The STA and RIV titers of the infected dogs in experiment 2 were significantly higher than were those of the dogs in experiment 1. Brucella abortus was isolated from 29 infected dogs in experiments 1 and 2 including 10 dogs, which were seronegative when cultured.     

Conservative treatment of an incomplete longbone fracture of a hindlimb of four horses

Four horses with an incomplete fracture of a hindlimb longbone were examined. In two, the tibia had been fractured by external trauma. In the other two horses proximal metatarsal 3 had fractured during normal activity. The diagnoses were made radiographically and the horses were treated conservatively by box rest. The fractures healed satisfactorily and the horses became sound.     

Evaluation of plate luting, using an in vivo ovine osteotomy model

Bilateral, midshaft metacarpal osteotomies were performed in 11 sheep and bilateral, midshaft radial osteotomies were performed in 7 sheep. The lesions were repaired with bone plates. One of each pair of plates was luted with polymethylmethacrylate and all screws were tightened uniformly with a torque screwdriver. Sheep were allowed unrestricted exercise after surgery. At 8 weeks, 10 of 11 sheep with metacarpal osteotomies were sound and both osteotomies were healing. Seven were lame on the limb with the unluted plate during the first 3 weeks; 4 were never lame on either limb. The screws of the unluted plates were significantly (P less than 0.01) looser at 8 weeks than those in the luted plates. All of the sheep with radial osteotomies were lame in the limb with the unluted plate. Four of 7 sheep had overt loosening of the unluted plates. One sheep only had mild screw loosening with continued alignment of the osteotomy. Two of 7 sheep fractured the radius with the luted plate; these 2 sheep were lame in the limb with the unluted plate and were using the limb with the luted plate vigorously. Excluding the 2 sheep with fractures, all had substantially more screw loosening in the unluted plate. Histologically, there were no discernible differences in the vascularity or porosity of the bone under the luted vs the unluted plates. The only adverse consequence of the luting technique was introduction of a small amount of polymethylmethacrylate into the osteotomy gap in 5 bones.     

Tropical theileriosis in Bos taurus and Bos taurus cross Bos indicus calves: response to infection with graded doses of sporozoites of Theileria annulata.

This work extends basic knowledge of tropical theileriosis in taurine and crossbred cattle. Infection of Bos taurus and Bos taurus cross Bos indicus (Sahiwal) calves with graded doses of sporozoites of Theileria annulata (Hissar), an Indian stock of the parasite, showed the following to be dose dependent in both cattle types: the time to appearance and population size of macroschizonts, microschizonts and piroplasms, time and severity of pyrexia, anaemia manifested by erythrocyte counts and haematocrit. All infections were accompanied by a prompt and severe panleucopenia. This effect was dose related in both the taurine and the Sahiwal crossbred calves. Lymphocyte counts returned to preinfection levels in the blood of animals which recovered, but death from theileriosis was characteristically accompanied by a persistent and severe lymphocytopenia. Flow cytometry using monoclonal antibodies to bovine mononuclear cells was used to identify the lymphocyte subsets involved in lymphocytopenia. The outcome of infection was dose dependent in the crossbred calves but not in taurine calves. Although the results obtained did not differ qualitatively between the two cattle types, they provided some preliminary evidence for resistance to tropical theileriosis in Sahiwal crossbred calves.     

Influence of diet on urine pH and the Feline urological syndrome

The hypothesis that feline urine pH can be manipulated by use of varying amounts of natural food components was tested. A relatively simple experimental model was constructed whereby soybean meal in a basal calculogenic diet was substituted by other components at varying levels and the changes in urine pH measured. In a different phase of the experiment the result of rapid change of diet was used to show the speed of response of urine pH. The effect of urine acidifying compounds was also demonstrated by the model. The prophylactic effect of three food components on urine pH was compared, with corn gluten meal the most potent. The model also demonstrated that feline urological syndrome (FUS) is possible in the presence of reduced levels of magnesium confirming previous work noting that the effect of urine pH is greater in the prevention of the condition than magnesium levels per se.     

The distribution of C-bands in canine transmissible venereal tumor cells

Colchicine-arrested metaphase preparations, derived from canine transmissible venereal tumor (TVT) cells grown in culture, were characterized based on the occurrence and distribution of constitutive heterochromatin. Analysis of the data with regard to the distribution of C-bands in the pericentric, interstitial and telomeric segments revealed a nonrandom distribution along the arms of many chromosomes with the bulk of the bands occurring in the centromeric region. The frequency of C-banded regions differed from those reported for normal dog cells and both primary and transplanted tumors. These results suggest that similar nondifferentially-stained TVT karyotypes do not necessarily exhibit identical distribution of constitutive heterochromatin.