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61.
Progressive ethmoidal haematomas (PEH) have been described as encapsulated, gradually expanding masses, which typically develop from the ethmoidal turbinates. Plain skull radiographs have been shown to be useful in determining the extent of the soft tissue mass if it invades the paranasal sinuses; however, where it is available, computed tomography (CT) offers substantial advantages in the evaluation of the full extent of a PEH. This Case Report describes a PEH invading into the sphenopalatine sinus, and the use of CT in accurately identifying the extent of the lesion. 相似文献
62.
Equine amnionitis and fetal loss: The case definition for an unrecognised cause of abortion in mares
KH Todhunter NR Perkins RM Wylie C Chicken AJ Blishen DJ Racklyeft G Muscatello MC Wilson PL Adams JR Gilkerson WL Bryden AP Begg 《Australian veterinary journal》2009,87(1-2):35-38
A series of abortions occurred in mares in New South Wales during 2004 that involved similar and unusual findings on post mortem examination of aborted fetuses and fetal membranes. The term Equine Amnionitis and Fetal Loss (EAFL) was developed to describe the condition. This form of abortion had not been previously recognised in Australia. The pathology alone is not specific for EAFL and diagnosis requires demonstration of a combination of certain pathological and bacteriological features. The purpose of this paper is to describe patterns considered consistent with EAFL cases as a working case definition for use by veterinarians and veterinary pathologists in identifying future cases of EAFL. More detailed papers are in preparation to fully describe the epidemiological, histopathological, and microbiological aspects of EAFL. 相似文献
63.
Gillian A. Perkins Laura B. Goodman Koji Tsujimura Gerlinde R. Van de Walle Sung G. Kim Edward J. Dubovi Nikolaus Osterrieder 《Veterinary microbiology》2009,139(3-4):375-378
A single nucleotide polymorphism in the equine herpesvirus 1 (EHV-1) DNA polymerase gene (ORF30 A2254 to G) has been associated with clinical signs of equine herpes myeloencephalopathy (EHM). The purpose of our study was to determine the odds ratio for this genetic marker and EHM using a panel of field isolates from North America collected over the past twenty-three years. EHV-1 isolates cultured at the Cornell University Animal Health Diagnostic Laboratory from 1984 to 2007 were retrieved along with their clinical histories. DNA was extracted from these EHV-1 cultures and allelic discrimination was performed using real-time PCR. The results were confirmed by sequencing of the target region in ORF30. PCR and sequencing were in 100% agreement and showed that 19 out of the 176 isolates had the ORF30 G2254 allele (11%), of which16 were EHM cases and 3 respiratory or abortion cases. The odds of having neurologic disease with the ORF30 G2254 genotype were computed as 162 times greater than those with the opposite allele ORF30 A2254 (95% confidence interval: 35–742). Despite this strong statistical significance, 24% (5/21) of horses with neurologic disease in our study population harbored the “non-neurologic” form of the allele (ORF30 A2254), suggesting that other factors may also contribute to the onset of EHM. 相似文献
64.
Neil R Smalheiser Vetle I Torvik Amanda Bischoff-Grethe Lauren B Burhans Michael Gabriel Ramin Homayouni Alireza Kashef Maryann E Martone Guy A Perkins Diana L Price Andrew C Talk Ruth West 《Journal of Biomedical Discovery and Collaboration》2006,1(1):8
Arrowsmith is a unique computer-assisted strategy designed to assist investigators in detecting biologically-relevant connections between two disparate sets of articles in Medline. This paper describes how an inter-institutional consortium of neuroscientists used the UIC Arrowsmith web interface http://arrowsmith.psych.uic.edu in their daily work and guided the development, refinement and expansion of the system into a suite of tools intended for use by the wider scientific community. 相似文献
65.
Musculoskeletal injuries (MSI) in racehorses have been identified as the most common cause of lost training days and weeks spent resting at pasture. Several training-, track- and horse-related risk factors have been identified. However, there is no clear understanding of the inter-relationship between these factors. The aim of this longitudinal cohort study was to investigate risk factors for MSI in 2-year-old Thoroughbred racehorses. Australian Thoroughbred trainers were convenience sampled and enrolled in a 27-month longitudinal cohort study. The study population consisted of all 2-year-old Thoroughbred racehorses trained by a participating trainer. Horses were followed from the time of enrollment until the completion of the study or until they were lost to follow-up. Trainers were visited at approximately 14-day intervals to collect training and injury data. Training days were categorised as fast days if the maximum speed during training exceeded 800 m/min. For each horse, the first training period that included one or more fast days was analysed. A multiple logistic regression model was used to determine those horse- and training-related variables that were associated with MSI. Data from 274 horses trained by 14 trainers at five racetracks were analysed. Forty percent of the horses sustained a MSI during their first fast preparation. The average distance trained at speeds >or=800 m/min and the percentages of fast days from the first fast day until the end of the preparation were the only variables associated with MSI. After accounting for these variables there were still significant differences between trainers. This suggests that there are other training-related variables such as the rate of increase in distance trained at speeds >or=800 m/min that may be risk factors for MSI. In addition, other factors such as the level of veterinary involvement and the training centre/racetrack may be risk factors for MSI. More analysis using multi-level modelling is required to determine the relationship between trainer- and track-related risk factors. 相似文献
66.
Maria Barrandeguy Julio Perkins Jorge Mac Donough Aldana Vissani Cecilia Olguin Etienne Thiry 《Journal of Equine Veterinary Science》2010
Equine coital exanthema (ECE) is an acute, venereal disease caused by equid herpesvirus 3 (EHV-3), characterized by the formation of papules, vesicles, pustules, and ulcers on the vaginal and vestibular mucosa as well as on the skin of the penis, prepuce, and perineal region of mares and stallions. The present work describes an outbreak of ECE characterized by typical lesions around the anus and on the perineal skin, discomfort, and anorectal lymphadenopathy, which occurred in a large number of donor and recipient mares at an embryo transfer center in Argentina. We found that the horses' movement pattern, the environmental conditions, and the management procedures could have favored the introduction and/or reactivation from latency and spread of EHV-3. Although this is the first report of an outbreak of ECE in an embryo transfer facility, it reinforces the need to introduce additional hygienic and preventive measures to avoid EHV-3 spread and future ECE outbreaks. 相似文献
67.
Perkins JD Meighan H Windley Z Troester S Piercy R Schumacher J 《Veterinary surgery : VS》2011,40(3):305-310
Objective: To determine whether ventriculocordectomy (VCE) performed before prosthetic laryngoplasty (PL) results in increased rima glottidis size compared with PL alone. Study Design: Experimental study. Animals: Equine cadaver larynges (n=13). Methods: Right arytenoid cartilages were maximally abducted using a standard PL technique. Standard PLs were then performed on the left side and the force required to maximally abduct the left arytenoid cartilage recorded (Fmax). Photographs were taken of the rima glottidis at zero force and at five equal levels of force up to Fmax. The force applied was released, left VCE performed, and photographs repeated. Arytenoid left:right angle quotients (LRQ) and glottic cross‐sectional area ratios (CSAR) were calculated at each force level in each condition (PL and VCE‐PL). Results: Mean LRQ and CSAR for both PL and VCE‐PL increased with increasing force, initially rapidly before plateauing at ~50% of Fmax. LRQ and CSAR were significantly greater for VCE‐PL than for PL (P<.001). When VCE was performed before PL, 12% less force was required to achieve an LRQ of 0.8, and 45% less for a CSAR of 0.8. Conclusions: In vitro, VCE performed before PL enables the arytenoid cartilage to be abducted to a greater degree for a given PL suture force. 相似文献
68.
VC McIver AS Tsang NE Symonds NR Perkins E Uquillas CM Dart LB Jeffcott AJ Dart 《Australian veterinary journal》2020,98(6):250-255
69.
An enzyme-linked immunosorbent assay (ELISA) was developed to measure total antibody to Toxoplasma gondii in serum samples from macropods. The validity of the assay was established by comparing parasite isolation in mice for 17 Tasmanian pademelons (Thylogale billardierii) and 17 Bennett's wallabies (Macropus rufogriseus rufogriseus). The ELISA was then used to detect antibody against T. gondii in serum from 236 macropods, collected from 21 locations in Tasmania, including Flinders Island. Antibody against T. gondii was detected in 20 animals (15 T. billardierii and 5 M. rufogriseus). There was a significant (p less than 0.01) difference in possession of T. gondii antibodies between adult (greater than or equal to 1 year of age) Tasmanian pademelons and Bennett's wallabies. 相似文献
70.
Nineteen does (female goats) were dosed with 500,000 oocytes of Hammondia hammondi prior to breeding. At about 90 days of gestation these, and 18 uninoculated does were challenged with 25,000 Toxoplasma gondii oocysts. The 19 H. hammondi--inoculated does produced 26 live and one dead kid (newborn goat). The 18 does not given H. hammondi produced 12 live and 19 dead kids. However, examination of all of the kids by isolation of T. gondii in mice, serology and histology revealed that they were all infected with T. gondii. Thus, while H. hammondi "vaccination" is protective against the deleterious effects of T. gondii on pregnant does, perhaps by reducing the severity of placental lesions, it does not prevent foetal infection. 相似文献