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81.
82.
A series of monoazo disperse dyes based on 2-amino-4-phenylthiazole was prepared using variousN,N-dialkylaniline derivatives as the coupling component. The dyes were characterized by IR spectral studies, visible absorption
spectroscopy and elemental analysis. The dyeing performance of these dyes was assessed on cellulose triacetate and nylon fibers.
These dyes were found to give a wide range of colour shades varying from bright red to royal blue with very good depth, brightness
and levelness on fibers. The dyed fibers showed good to very good light fastness and very good to excellent fastness to washing,
perspiration, rubbing and sublimation. The dyebath exhaustion and fixation on the fibers were found to be very good. 相似文献
83.
Henrik Harms Barbora Orlikova Seungwon Ji Damun Nesaei-Mosaferan Gabriele M. K?nig Marc Diederich 《Marine drugs》2015,13(8):4949-4966
The Ascomycota Dichotomomyces cejpii was isolated from the marine sponge Callyspongia cf. C. flammea. A new gliotoxin derivative, 6-acetylmonodethiogliotoxin (1) was obtained from fungal extracts. Compounds 2 and 3, methylthio-gliotoxin derivatives were formerly only known as semi-synthetic compounds and are here described as natural products. Additionally the polyketide heveadride (4) was isolated. Compounds 1, 2 and 4 dose-dependently down-regulated TNFα-induced NF-κB activity in human chronic myeloid leukemia cells with IC50s of 38.5 ± 1.2 µM, 65.7 ± 2.0 µM and 82.7 ± 11.3 µM, respectively. The molecular mechanism was studied with the most potent compound 1 and results indicate downstream inhibitory effects targeting binding of NF-κB to DNA. Compound 1 thus demonstrates potential of epimonothiodiketopiperazine-derived compounds for the development of NF-κB inhibitors. 相似文献
84.
Claire Bouvard Isabelle Galy-Fauroux Fran?oise Grelac Wassila Carpentier Anna Lokajczyk Sophie Gandrille Sylvia Colliec-Jouault Anne-Marie Fischer Dominique Helley 《Marine drugs》2015,13(12):7446-7462
Low-molecular-weight fucoidan (LMWF) is a sulfated polysaccharide extracted from brown seaweed that presents antithrombotic and pro-angiogenic properties. However, its mechanism of action is not well-characterized. Here, we studied the effects of LMWF on cell signaling and whole genome expression in human umbilical vein endothelial cells and endothelial colony forming cells. We observed that LMWF and vascular endothelial growth factor had synergistic effects on cell signaling, and more interestingly that LMWF by itself, in the absence of other growth factors, was able to trigger the activation of the PI3K/AKT pathway, which plays a crucial role in angiogenesis and vasculogenesis. We also observed that the effects of LMWF on cell migration were PI3K/AKT-dependent and that LMWF modulated the expression of genes involved at different levels of the neovessel formation process, such as cell migration and cytoskeleton organization, cell mobilization and homing. This provides a better understanding of LMWF’s mechanism of action and confirms that it could be an interesting therapeutic approach for vascular repair. 相似文献
85.
Amaya-Guerra CA Alanis-Guzman MG Serna Saldívar SO 《Plant foods for human nutrition (Dordrecht, Netherlands)》2004,59(2):45-50
The physiological development of laboratory rats fed with a typical indigenous tortilla diet was studied for two generations. The experiment compared casein control diet and five different types of diets: (1) a diet of tortillas obtained from fresh masa (FM); (2) regular tortillas produced from enriched dry masa flour containing vitamins B1, B2, niacin, folic acid, and the microminerals iron and zinc (REDMF); (3) tortillas produced from enriched dry masa flour fortified with 6% defatted soybean meal (FEDMF); (4) tortillas produced from enriched quality protein maize flour (EQPM); and (5) and, tortillas produced from enriched quality protein maize flour fortified with 3% defatted soybean meal (FEQPM). The growth of rats fed FEDMF and FEQPM diets was significantly higher (P<0.05) in both generations than their counterparts fed EQPM, REDMF, or FM diet. Animals fed quality protein maize (QPM) tortilla had the highest protein digestibility, but the FEQPM and FEDMF diets had the highest biological value (BV), net protein utilization (NPU), and protein-digestibility-corrected EAA scores (PDCEAAS). The difference among treatments was more evident in the second-generation rats. The pregnancy rate, number of newborns/litter, litter weight, and newborn survival rate was also higher for rats fed FEDMF, EQPM, and FEQPM diets than their counterparts fed REDMF and FM. 相似文献
86.
The development of high tenacity, high modulus monofilaments from Polypropylene/Clay nanocomposite has been investigated.
Pure sodium montmorillonite nanoclay was modified using hexadecyl trimethyl ammonium bromide (HTAB) via an ion exchange reaction.
Pure and modified clay were characterized through X-ray diffraction, FTIR and TGA. The modified clay was melt blended with
polypropylene (PP) in presence of a swelling agent. Composite filaments from PP/Clay nanocomposite were prepared at different
weight percentages of nanoclay and the spinning and drawing conditions were optimized. The filaments were characterized for
their mechanical, morphological and thermal properties. The composite PP filaments with modified clay showed improved tensile
strength, modulus and reduced elongation at break. The composite filaments with unmodified clay did not show any improvement
in tensile strength but the modulus improved. The sharp and narrow X-ray diffraction peaks of PP/nanoclay composite filaments
indicate increase in crystallinity in presence of modified clay at small loadings (0.5%). The improved thermal stability was
observed in filaments with modified as well as unmodified clays. 相似文献
87.
Barbara M. Rezende Priscila T. T. Bernardes Carolina B. Resende Rosa M. E. Arantes Danielle G. Souza Fern?o C. Braga Marina G. M. Castor Mauro M. Teixeira Vanessa Pinho 《Marine drugs》2013,11(7):2595-2615
Lithothamnion muelleri (Hapalidiaceae) is a marine red alga, which is a member of a group of algae with anti-inflammatory, antitumor, and immunomodulatory properties. The present study evaluated the effects of treatment with Lithothamnion muelleri extract (LM) in a model of acute graft-versus-host disease (GVHD), using a model of adoptive splenocyte transfer from C57BL/6 donors into B6D2F1 recipient mice. Mice treated with LM showed reduced clinical signs of disease and mortality when compared with untreated mice. LM-treated mice had reduced tissue injury, less bacterial translocation, and decreased levels of proinflammatory cytokines and chemokines (interferon-γ (IFN-γ), tumor necrosis factor-α (TNF-α), chemokine (C-C motif) ligand 2 (CCL2), chemokine (C-C motif) ligand 3 (CCL3) and chemokine (C-C motif) ligand 5 (CCL5)). The polysaccharide-rich fraction derived from LM could inhibit leukocyte rolling and adhesion in intestinal venules, as assessed by intravital microscopy. LM treatment did not impair the beneficial effects of graft-versus-leukaemia (GVL). Altogether, our studies suggest that treatment with Lithothamnion muelleri has a potential therapeutic application in GVHD treatment. 相似文献
88.
夷优180系福建省南平市农业科学研究所用自主选育的三系不育系夷A与恢复系南恢180配组而成的杂交中稻新品种。经多年在福建省各地试验、试种表现群体整齐、适应性广、产量高、抗性好等特点,2014年通过福建省农作物品种审定。简述了杂交水稻夷优180的选育及应用。 相似文献
89.
Wojciech Czajkowski Justyna Mamnicka Wies?awa Lota Joanna Lewartowska 《Fibers and Polymers》2012,13(7):948-953
A number of water-soluble colourless fibre-reactive UV-absorbers derivatives of symmetrical triazine were used as additives during commercial laundering process. UV-protection factor (UPF) of such treated cotton tricot samples was measured. Changes in protection properties of modified textiles after repeated standard laundering process were determined. Carried-out experiments gave evidence of covalent bond formation between applied absorbers and cellulose fibre during standard washing process at 40 °C or 60 °C. Textiles modified by this method have provided UV-protective properties for prolonged time. 相似文献
90.
Xueli?Ding Yunfa?Qiao Timothy?Filley Haiying?Wang Xinxin?Lü Bin?ZhangEmail author Jingkuan?WangEmail author 《Biology and Fertility of Soils》2017,53(3):281-286
To test the impact of a range of long-term land use types on the partitioning of microbial residues among soil particles, samples from a Mollisol with plots under 100 years of continuous arable cropping, 30 years of simulated overgrazing to severely degraded bare soil, or 30 years of grassland restoration were investigated. The microbial residues, which were assessed among three particle-size fractions (<2, 2–20, and 20–250 μm) by amino sugar extraction, exhibited change with particle size and land use. Converting arable cropping to bare soil induced substantial depletion of amino sugars associated with the clay-size fraction, as a proportion of total carbon (C) and total soil mass, but not the silt- and sand-size fractions. Alternatively, switching arable soil to grassland increased amino sugar stocks in both the clay- and sand-size fractions. Analysis of the relative input of fungal and bacterial derived amino sugars indicated that fungal sources are the most dynamic with respect to land use change. These results highlight the selective vulnerability of microbial C pools in finer fractions under low plant C input and the selective recovery in specific fractions upon restoration, emphasizing the importance of the conversion of plant organic matter into mineral-associated microbial residues to promote stable soil organic C. 相似文献