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941.
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WEI Yan-ling NIU Chun-yu ZHAO Zi-gang LIU Zhi-quan ZHANG Yu-ping ZHANG Jing 《园艺学报》2010,26(8):1509-1514
AIM: To observe the effects of mesenteric lymph duct ligation and mesenteric lymph drainage on the vascular reactivity and calcium sensitivity in hemorrhagic shock (HS) rats, and to investigate the role of mesenteric lymph on the vascular hyporeactivity during shock. METHODS: Seventy-two male Wistar rats were randomly divided into sham group (only operation), shock (duplicating HS model) group, shock+ligation group (duplicating HS model and mesenteric lymph duct ligation) and shock+drainage group (duplicating HS model and mesenteric lymph drainage). The changes of mean artery pressure (MAP) after injection of norepinephrine (NE, 3 μg/kg) at different time points were recorded. After hypotension (40 mmHg) for 3 h, the vascular ring of superior mesenteric artery (SMA) was made for determining the vascular reactivity and sensitivity to calcium by observing the contraction initiated by NE and Ca2+ under depolarizing conditions (120 mmol/L K+) in the isolated organ perfusion system. Meanwhile, the effects of angiotensin Ⅱ (AngⅡ) and insulin (Ins) on the vascular reactivity were also observed. RESULTS: Compared to sham group, the △MAP in shock group was increased significantly at 0 h and 0.5 h after shock, and that was decreased markedly at 1.5 h, 2 h, 2.5 h and 3 h after shock, respectively, and that in shock+ligation group and shock+drainage group was increased at 0 h, 0.5 h and 1 h after shock, decreased at 2.5 h and 3 h after shock, respectively. The △MAP in shock+ligation group and shock+drainage group was higher than that in shock group at 0.5 h after shock and all the time points followed. The SMA reactivity to NE and sensibility to Ca2+ in shock group, shock+ligation group and shock+drainage group were lower markedly than those in sham group. The vascular reactivity and calcium sensitivity in shock+ligation and shock+drainage groups were higher than those in shock group. The vascular reactivity and calcium sensitivity in shock group, shock+ligation group and shock+drainage group were lower than those in sham group, and those in shock+ligation and shock+drainage groups were increased as compared to shock group, respectively. CONCLUSION: Blockage of mesenteric lymphatic return with the methods of mesenteric lymph duct ligation and mesenteric lymph drainage promotes the vascular reactivity of HS rats. The mechanism may be related to improving the calcium sensitivity in the vasculature. 相似文献
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Pathological pain or clinical pain is caused by tissue and nerve injuries, and is usually chronic and mainly divided into inflammatory pain and neuropathic pain. Pathological pain is typically characterized by hyperalgesia (increased responsiveness to noxious stimuli) and allodynia (painful responses to normally innocuous stimuli). The mitogen-activated proteins kinases (MAPKs) are a family of evolutionally conserved molecules that play a critical role in cell signaling, consisting of extracellular signal regulated kinase (ERK), p38, and c-Jun N-terminal kinase (JNK), which play an important role in neural plasticity of pathological pain. Inhibition of MAPKs alleviates inflammatory pain and neuropathic pain in different animal models. It is very important to study the inhibition of MAPKs as a therapeutic approach to treat pathological pain. 相似文献
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粘类小麦雄性不育系F_1结实性状的遗传分析 总被引:1,自引:0,他引:1
采用MINQUE统计方法、加性-显性(AD)及其与环境互作的遗传模型,对粘类小麦雄性不育系和恢复系杂交F1小穗两边结实数、中间结实数等结实性状进行了分析。结果表明,粘类小麦雄性不育系育性恢复性主要以加性效应为主,其次是显性效应,加性方差占表现型方差的比例变幅为38%~48%;不育系(V)-90-110、(Ven)-90-110、(K)-224、(V)-224所配制的组合,在2个结实性状上,包括国内法、国际法,平均结实率均具有正向显著或极显著的加性效应,亲本5253、02-7-215、00-6-247、M8003具有使不育系恢复度提高的加性效应;双亲加性效应高的组合多数表现出其显性效应比较差;国际法恢复度高的组合(K-224×5253),究其原因是双亲国际法恢复度的加性效应高,尤其亲本5253国际法恢复度的加性效应在供试材料中是最高的,其显性效应也较高(36.14%);粘类小麦雄性不育系杂交结实率的高低与环境的互作相对较小,育性恢复性在年份间的表现比较稳定。 相似文献
949.
黄淮海(南片)夏玉米高产高效栽培技术规程 总被引:8,自引:0,他引:8
本规程以高产、抗病、抗倒、稳产品种为核心,以精细播种、提高播种质量为基础;以中高密度为保证;以加强肥水调控为重点,以实现品种、技术和生态气候三个因素的最佳结合为目的,以技术、环境、产量指标与产量形成的动态关系为生长调控主线, 相似文献
950.
休闲农业作为拓展城市旅游的朝阳产业,满足了城市居民日益增长的游憩需求,同时也为城市发展提供了未来储备。笔者以郑州市为例,综合空间地域、分布类型、交通可达性等多种因素,对郑州市休闲农业的空间特征进行分析评价,并针对休闲农业存在的问题,从规划合理性、类型多样性、空间可达性和提高参与性等方面提出了一些建议,旨在推动郑州市休闲农业的合理化均衡化发展,同时也为城市规划、旅游规划、政府合理优化景点布局等提供参考。 相似文献