Cardiomyopathy in Dystrophin-Deficient Hypertrophic Feline Muscular Dystrophy

A colony of cats affected with hypertrophic feline muscular dystrophy was used to study the occurrence of cardiomyopathy associated with dystrophin deficiency. Affected male and female cats, obligate carrier females, and unaffected healthy littermates were followed from 12 weeks of age into adulthood. Thoracic radiography, 2-D echocardiography, and 2-D-derived M-mode echocardiography were performed at 3-month intervals until 12 months of age and regularly thereafter. From 9 months of age, all affected cats had larger hearts than normal and carrier animals. Left ventricular wall thickness in systole and in diastole and interventricular septal thickness in systole were greater in affected cats 12 months and older when compared with normal or heterozygous animals (P < .05). The myocardium of affected cats was diffusely hypoechoic and thickened. Multiple hyperechoic foci were in the myocardium and papillary musculature. Shortening fraction was normal in all cats. Changes seen in carrier females included enlargement and hyperechogenicity of the papillary musculature after the age of 2 years. Gross and light microscopic examination revealed left ventricular wall thickening with multiple foci of mineralization in 2 of 5 hearts from dystrophin-deficient cats. Although approximately 10% of the normal dystrophin amount was present in the skeletal muscle, dystrophin could not be detected in the myocardium. Early onset concentric myocardial hypertrophy was present in all adult cats. Lesions were mainly localized in the myocardium of the left ventricular free wall and interventricular septum, papillary musculature, and the endocardium. Clinical signs of heart failure developed only infrequently in cats with hypertrophic feline muscular dystrophy.     

Regulation of fibroblast growth factor 9 on the differentiation of goat intramuscular adipocytes

It has been found that fibroblast growth factor receptor (FGF-FGFR) signaling can regulate the expression of adipocyte differentiation genes. FGF9 is one of the members of FGFs that mainly binds receptors FGFR2 and FGFR3. FGF9 is highly expressed in the adipose tissue of humans and mice, but there are few reports on the role of FGF9 in goat intramuscular adipocyte differentiation. Therefore, this study explored the effect of FGF9 on adipocyte differentiation through cell culture, interference, and overexpression. The expression of receptors FGFR1–FGFR4 in adipocyte differentiation and their effects on differentiation were detected to screen receptor gene of FGF9. Finally, the interaction between FGF9 and the receptor was tested by cotransfection. Our results showed that FGF9 interacts with FGFR2 to inhibit goat intramuscular adipocyte differentiation by regulating peroxisome proliferator-activated receptor gamma (PPARγ) and preadipocyte factor 1 (Pref1), which is a data support for subsequent pathway research.     

羊的同期发情技术

论述了羊的同期发情技术原理、供受体同期发情处理方法、供受体发情时间以及发情检测方法,提出了羊的同期发情技术的应用范畴.     

奶牛杂交群体及其遗传评估的模拟研究

为验证在奶牛杂交群体中将品种组成和杂合度作为协变量的遗传评估理论,为奶牛杂交模式选择和杂交群体遗传评估等实际问题提供理论依据,结合我国奶业现状,本研究模拟了在低产荷斯坦牛群引入法系蒙贝利亚牛、德系西门塔尔牛进行杂交,采用随机交配和三品种轮回杂交模式、群体世代重叠17年的繁育过程.群体杂合度在第7年后趋于平衡,轮回杂交模式的群体杂合度高于随机交配.经过杂交,原中低产荷斯坦牛群体在产奶性能、生长性能方面都有进展,轮回杂交提高幅度相对略高.此外,利用品种效应和杂合度效应剖分杂种优势,采用单性状和多性状动物模型对模拟群体进行遗传评估,效果基本一致,都可以很好地用于杂交群体的遗传评估.结果表明,对荷斯坦牛中低产群体进行杂交,可实现生产性能和效益的提高,回归模型可用于多元群体的遗传评估.     

草原生态保护红线划定的基本思路与政策建议

草原保护事关我国生态及经济协调、可持续发展大局。划定草原生态保护红线是构筑我国生态安全屏障的基础,是加强我国民族团结和边疆稳定的前提,是确保我国畜牧业产业安全的保证,是实现牧区可持续发展的重要保障。草原生态保护红线与耕地保护红线一样,具有不可撼动的国家战略意义和重大历史意义。本文在分析我国草原保护现状及存在问题的基础上,提出了草原生态保护红线的内涵和意义,阐述了划定生态红线的基本思路,给出了实现草原可持续发展、划定草原生态保护红线的具体政策建议。     

老年犬的养护

如果家里有一头老年犬,它一定陪伴你走过了好几个年头,在这么多年里它也许是你的精神寄托;有了它你的生活更快乐了,是它提高了你的生活品质。这个时候,它仍然在你的身旁,但它已经不像年轻时那样爱玩爱闹了,对事情的注意力、警惕性也有明显下降。这些都是不可避免的,你深爱的犬正在逐渐衰老。这个时候,它的需求正在变化,它对你的依赖越来越强,它需要你给它保持一个健康的身体和安逸的老年生沽。     

家禽脂肪营养研究进展

脂肪代谢能值高,且是必需脂肪酸的来源,在家禽营养中发挥着重要的作用。饲料中添加合适的脂肪能改善家禽的生产性能、屠体品质、免疫性能、产蛋性能、蛋品质及繁殖性能。本文综述了国内外近十年关于脂肪在肉禽、蛋禽和种禽上的研究报道,旨在为脂肪在家禽饲料中的合理应用提供科学依据。     

紫花苜蓿灌溉的理论与技术

本文系统地阐述了紫花苜蓿灌溉的理论与技术,内容包括需水量、需水强度、入渗速率、灌溉需要量、灌溉定额、灌水深度、灌水定额、灌水周期、灌水次数、灌水时期、灌水强度、灌溉方法等内容。     

基于TM和ASTER的植被指数建模性能对比

在对TM、ASTER数据进行多种植被指数生成的基础上,结合研究区48个杨树样地的测树因子数据,分别就杨树单位面积蓄积量、杨树平均高和杨树年龄进行了遥感统计建模研究,通过植被指数及其变形式共65个特征对比结果表明,由ASTER数据派生的植被指数中RVI3(0.5)对于上述3个测树因子的估测性能最好,由TM数据导出的植被指数中则是DVI2对上述3个测树因子回归效果最好,从建模性能上分析,ASTER数据生成的植被指数要优于TM数据生成的植被指数。