Protection of dogs against death from experimental rabies by postexposure administration of rabies vaccine and hyperimmune globulin (human).

Two experiments on simulated postexposure treatment were carried out in dogs using human rabies immunoglobulin (RIGH) and human diploid cell vaccine for human use. In one experiment, when animals were challenged by injecting street virus into the masseter muscle and treated with a combination of RIGH and vaccine, 50% of the animals were protected from rabies. In the other trial, in which animals were challenged by injecting the virus into the femoral muscle, treatment with RIGH and vaccine protected all the animals against rabies. To our knowledge this is the highest rate of postexposure survival in animals reported to date. In addition, five out of eight (62.5%) dogs that received RIGH alone after the virus challenge were protected, while none of the animals receiving vaccine alone were protected from rabies. These trials suggest that animals can be protected from rabies by postexposure treatment. The route of exposure and timing of the administration of vaccine and hyperimmune serum would seem to be important.     

Reproduction of proliferative enteritis in gnotobiotic pigs

Gnotobiotic pigs dosed orally with filtrates (0.8 and 0.65 micron) of intestinal mucosa from a pig affected by proliferative haemorrhagic enteropathy developed lesions of proliferative enteritis, affecting mainly the ilea. Other piglets dosed with filtrates of affected mucosa from the same source and from other proliferative haemorrhagic enteropathy or intestinal adenomatosis mucosae, did not develop lesions. All inocula contained numerous campylobacter-like organisms evident in stained smears, Campylobacter coli and C mucosalis. C coli colonised the intestines of all the pigs, C hyointestinalis (which was not detected in the inocula) did so in some affected and unaffected pigs while C mucosalis was not recovered from any of the intestines. Although other explanations are possible the number and viability of the intracellular campylobacter-like forms is likely to be the critical factor in infectivity. In affected intestines the crypts were colonised by campylobacter-like organisms, and their attachment and entry into enterocytes was associated with cellular proliferation. Immunofluorescence reactions suggested that the intracellular campylobacter-like organisms were antigenically distinct from the known Campylobacter species. It is possible, therefore, that porcine proliferative enteritis is caused by a further unidentified Campylobacter species, or that there is a marked antigenic change of C hyointestinalis or C coli on entry into porcine enterocytes.     

Serological diagnosis of the porcine proliferative enteropathies: implications for aetiology and epidemiology

Campylobacter mucosalis and C hyointestinalis have been associated with the proliferative enteropathies of pigs. An examination of the antibody response to these organisms and to the intracellular campylobacter-like organism was undertaken. Antibody to the campylobacter-like organism was predominantly IgM, short lived, and could be detected by an immunofluorescence test using bacteria released from lesions as antigen. The majority (75 per cent) of pigs with proliferative enteropathy at necropsy were antibody positive and a small number (4 per cent) of pigs in which lesions were not observed were found to have antibody. Antibody appeared to be correlated with the presence of lesions rather than with exposure to infection and was independent of the presence of antibody to C mucosalis or C hyointestinalis. In natural outbreaks of the disease antibody to the campylobacter-like organism was more prevalent than clinical signs in the affected animals.     

Proliferative haemorrhagic enteropathy.

This study indicates that viable Campylobacter sputorum subsp mucosalis are not present or are present in small numbers in the mucosa of pigs dying of proliferative haemorrhagic enteropathy. The changes present in the mucosa are similar to those seen in pigs recovering from adenomatosis and the evidence obtained indicates that the intracellular organisms observed in this condition are indeed mucosalis. The presence of large amounts of IgA in the altered tissue of both proliferative haemorrhagic enteropathy and porcine intestinal adenomatosis indicates that the failure to recover bacteria may be immunologically mediated but is not simply related to the presence or absence of antibody in the respective conditions.     

The use of Pulse Monitors in Dogs and Cats

Abstract— A report is presented of a limited study on the possible application of electronic pulse meters in the dog and cat. Three instruments of two different types were examined. Two instruments were found satisfactory when used as pulse monitors, while only one could be used successfully to measure systolic blood pressures. The instruments are most useful for anaesthetized animals applied to either the tail or a limb.
Résumé— –On fait le compte-rendu d'une courte étude sur l'application possible d'un compteur de pouls électronique chez le chien et le chat. On examina trois instruments de deux types différents. Deus d'entre eux se montrèrent satisfaisants quand on les utilisa pour contrôler le pouls, tandis qu'un seul put être employé avec succès pour mesurer la tension artérielle systolique. Ces instruments sont très utiles chez les animaux anesthésiés où on les applique sur la queue on sur un membre.
Zusammenfassung— Es wird Bericht erstattet über eine begrenzte Untersuchung einer möglichen Verwendung von elektronischen Pulsmessern bei Hunden und Katzen, Es wurden drei Instrumente zweier verschiedener Typen einer Prüfung unterzogen. Zwei Instrumente wurden als brauchbar für die Pulsüberwachung befunden, während nur eines mit Erfolg zur Messung des systolischen Blutdruckes verwendet werden konnte. Die Instrumente werden am besten bei in Narkose befindlichen Tieren entweder am Schwanz oder an einer Extremität angebracht.     

山西沁河上游河岸植被缓冲带评价与恢复重建研究

在对河岸带特性进行调查的基础上,针对我国北方河岸带的特点.提出了从植被结构完整性和河岸结构稳定性两方面的14个指标组成的河岸带植被结构和功能评价体系、对山西省沁河的一级支流赤石桥河和紫红河的河岸带植被进行了评价;同时进行河岸缓冲带恢复重建试验,研究了不同恢复措施下纯草、乱石滩、纯灌三种沁河上游河岸带典型地块的植被恢复效...