大电流电流源实现方法

提出2种大电流可控电流源方法:对于输出中小电流电流源,对通用的串联式线性调整可控电流源进行改进,降低调整管的温升;对于输出大电流的电流源,采用PWM控制方法,使调整管工作处于开关状态,调整管的功耗很小,温升低.根据上述方法,分别制作1台样机并进行性能测试,实践证明这2种方法是可行的.     

二维结合彩色多普勒超声对诊断乳腺肿块的价值

目的探讨二维及彩色多普勒超声(CDFI)对乳腺肿块鉴别诊断的价值。方法120例女性患者,术前应用二维超声观察乳腺肿块的大小、形态、位置、边界、包膜、内部回声;采用CDFI检测肿块周边及内部的血流形态、特点,并将彩色血流分为0~Ⅲ级。结果超声诊断乳腺肿块检出率为100%,良、恶性肿瘤超声诊断符合率分别为88.5%、85.7%。良性肿瘤多表现为边界光滑,侧缘回声减弱,CDFI血流分级以Ⅰ~Ⅱ级为主;恶性肿瘤多表现为形态不规则,边界不清,内部回声不均,CDFI血流分级以Ⅱ~Ⅲ级为主。恶性组的收缩期峰值流速(Vmax)、阻力指数(RI)、搏动指数(PI)分别为(28.2±7.3)cm/s、(0.78±0.09)、(1.8±0.3),良性组则分别为(13.5±6.7)cm/s、(0.63±0.07)、(1.2±0.2),差异均有统计学意义(P<0.01)。结论二维超声联合CDFI在乳腺良恶性肿瘤的鉴别诊断中有较高的应用价值。     

浅谈电子阅览室的建设

本文主要从运行环境、管理和安全问题探讨电子阅览室的建设。     

单宁-醛-胶原的反应——对植醛结合鞣机理的再认识

以黑荆树单宁为植物鞣剂，嗯唑烷为醛鞣剂，较系统地研究了氢键、疏水键、胶原氨基在植鞣、醛鞣和植-醛结合鞣中的作用。证实了植-醛结合鞣的反应机理与已有的认识有很大的区别。醛类化合物即使在植鞣后加入，其主要的反应基团仍然是皮胶原的氨基。但是当单宁分子中含有亲核活性较高的反应基团时，醛类化合物可以在皮胶原和单宁分子之间形成交联键。这种交联作用可以对提高皮胶原的热稳定性产生协同效应，而且使单宁与皮胶原的结合稳定性进一步加强，能够抵御氢键破坏试剂和疏水键破坏试剂的作用。采用缩合类单宁时，容易形成胶原-醛-单宁交联键；但采用水解类单宁时，形成这种交联键的几率很小。     

果胶酶酶解红枣制汁工艺的研究

以红枣为原料,采用果胶酶酶解浸提的方法制备红枣汁。以红枣汁可溶性固形物含量为参考指标,通过单因素试验和正交试验,研究了果胶酶添加量、酶解时间、酶解温度和p H值对枣汁浸提效果的影响。结果表明,最佳酶解工艺如下:果胶酶添加量为0.3%,酶解时间为4h,酶解温度为55℃,最适p H值为3.5,此工艺条件下所获得的红枣汁可溶性固形物含量为15.87%,所得红枣汁枣香浓郁,无苦味,颜色红亮,稳定性好。     

剪枝再生对不同辣椒品种植株生长及产量的影响

针对3个不同类型的辣椒品种开展了剪枝再生栽培试验。结果表明,苏椒958不适宜剪枝再生栽培;镇研早翠和镇研20号剪枝再生后病毒病发生率较低,产量比秋茬栽培增产均达显著以上水平,并均高于春茬栽培,始收期提早6 d,适宜剪枝再生栽培,且镇研20号的果实性状变化不大。     

2004—2013年我国空间格局分析的方法-点格局分析法研究文献分析

为了解我国近十年来点格局分析法方面的研究现状,采用文献计量学等统计方法,对2004—2013年我国空间格局分析的方法-点格局分析法研究方面的文献进行了分类统计分析。结果共检索出点格局分析法方面的文献232篇。其中不同期刊的载文分布,发文量达10篇以上的期刊有5种,占32.33%。不同年份发文量,2004年发表的文献量最少,仅3篇;2012年最多,达到41篇。不同第一作者发文量,发文量少于5篇的作者最多,占59.48%;发文量为5篇的有9人,占19.40%;发文量为6~9篇的有5人,占16.38%;发文量为10篇或以上的仅1人,占4.74%。作者机构分布,在所搜集的232篇文献中,有9个机构在此期间发表的论文7篇,占71.55%。文献的研究层次,基础与应用基础研究的发文量最多,占93.10%。     

斜纹夜蛾性诱剂不同使用方法对诱蛾量的影响

通过对性诱剂及诱捕器不同悬挂使用方法对诱蛾量的影响进行应用观察研究,以期明确性诱剂诱捕器摆放高度、间距等较为合理的使用方法。试验结果表明,诱捕器在时间、气候条件等相同情况下,放置在作物顶端上方30~50 cm,诱蛾量最大;从节本和诱蛾效果来看,放置间距以50~80 m为宜;诱芯以单放为宜。     

Effects of maternal limb ischemic preconditioning on structural and functional changes of mitochondria in fetal hippocampal neurons induced by intrauterine distress-reoxygenation in rats

AIM: To investigate the effects of maternal limb ischemic preconditioning (LIP) on the mitochondrial structures and functions of the hippocampal neurons induced by reoxygenation in the intrauterine distress fetal rats. METHODS: Pregnant rats (n=40) were randomly divided into 4 groups: sham (S) group, LIP group, fetal distress (FD) group and LIP+FD group. Intrauterine ischemia model was established through the experimental design. The ultrastructure of the mitochondria in CA1 area of the hippocampus was observed. The mitochondrial membrane potential and reactive oxygen species (ROS) were measured. The content of ATP and MDA in the hippocampus tissue was detected. The activity of Mn-SOD was observed. RESULTS: Compared with sham group, the ultrastructure of mitochondria in CA1 area of the hippocampus was damaged in FD group and LIP+FD group. The mitochondrial membrane potential, the content of ATP and the activity of Mn-SOD were decreased. However, the content of ROS and MDA was increased. Compared with FD group, the ultrastructure of mitochondria in CA1 area of the hippocampus was intact in LIP+FD group. Furthermore, the reduced mitochondrial membrane potential and ATP content were inhibited. The activity of Mn-SOD was increased, but the content of ROS and MDA was decreased in LIP+FD group. CONCLUSION: Limb ischemia preconditioning inhibits the damage the mitochondria of fetal hippocampal neurons induced by reoxygenation in the intrauterine distress fetal rats.     

Effect of microRNA-155 on regulation of angiogenesis in diabetic rats with cerebral ischemic injury

AIM: To evaluate the effect of microRNA-155(miRNA-155) on the regulation of angiogenesis in diabetic rats with cerebral ischemic injury. METHODS: Adult male Sprague-Dawley rats were randomly divided into 5 groups:sham group, cerebral ischemia group, diabetic cerebral ischemia group, diabetic cerebral ischemia+miRNA-155 inhibitors group and diabetic cerebral ischemia+scramble group. Diabetes model was made by injection of streptozocin and permanent cerebral ischemic model was developed by suture-occluded method. The scores of neurological deficit and infarct volume were estimated at 24 h after cerebral ischemia. miRNA-155 level was detected by real-time polymerase chain reaction. The expression of platelet endothelial cell adhesion molecule-1(PECAM-1/CD31) and vascular endothelial growth factor(VEGF) was detected by Western blotting. RESULTS: miRNA-155 inhibitor significantly reduced miRNA-155 levels in the ischemic cortex(P<0.05), improved the scores of neurological deficit, reduced infarction size and upregulated the levels of CD31 and VEGF(P<0.05). CONCLUSION: miRNA-155 has a critical role in the regulation of angiogenesis in diabetic rats with cerebral ischemia. Down-regulation of miRNA-155 using miRNA-155 inhibitor attenuates brain infarct injury in diabetic rats.