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991.
992.
Dongjoon Choi Taesik Yun Dohee Lee Yoonhoi Koo Yeon Chae MhanPyo Yang ByeongTeck Kang Hakhyun Kim 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2022,36(4):1330
BackgroundAn imbalance in adipokines is associated with the progression of chronic kidney disease (CKD) in humans. However, alterations in adipokines in dogs with CKD remain unclear.ObjectivesTo examine whether adipokine concentrations in serum differ between healthy dogs and dogs with CKD and to determine the correlation between serum adipokine concentrations and CKD severity in dogs.AnimalsTwenty dogs with CKD and 10 healthy dogs.MethodsIn this cross‐sectional study, serum concentrations of leptin, adiponectin, interleukin (IL)‐6, IL‐10, IL‐18, and tumor necrosis factor (TNF)‐α were measured in healthy dogs and dogs with CKD, which were classified according to the International Renal Interest Society guidelines.ResultsSerum leptin concentrations were positively correlated with systolic arterial blood pressure (r = .41), creatinine concentrations (r = .39), and symmetric dimethylarginine concentrations (r = .73). Serum adiponectin concentrations (median [range]) in CKD dogs with borderline or non‐proteinuric (20.25 [14.9‐45.8] ng/mL) were significantly higher than those in proteinuric CKD dogs (13.95 [6.4‐22.1] ng/mL; P = .01). Serum IL‐6 (median [range]; 43.27 [24.30‐537.30] vs 25.63 [6.83‐61.03] pg/mL; P = .02), IL‐18 (median [range]; 25.98 [11.52‐280.55] vs 10.77 [3.53‐38.45] pg/mL; P = .01), and TNF‐α (median [range]) concentrations (11.44 [8.54‐38.45] vs 6.105 [3.97‐30.68] pg/mL; P = .02) were significantly different between proteinuric and borderline or non‐proteinuric CKD dogs.Conclusions and Clinical Importanceleptin and adiponectin concentrations in serum might be associated with severity of CKD and proteinuria in dogs with CKD, respectively. 相似文献
993.
Permethrin resistance in 16 field populations of Colorado potato beetle was established by bioassay. Permethrin-resistant genotypes were detected using two genotyping techniques, bidirectional polymerase chain reaction amplification of specific alleles (bi-PASA) and single stranded conformational polymorphism (SSCP). The bi-PASA technique was 86% and SSCP was 95% reliable. In terms of accuracy, bi-PASA determined the correct genotype compared to the actual sequencing data 98% and SSCP 93% of the time. There was marked correlation between increasing survivorship (increasing LD50values) and increasing proportions of resistant genotypes (increasing percentage of resistant allele). These techniques allowed the detection of a resistant allele 98% of the time when sampling only 384 beetles from an overwintering adult population (4995 beetles/ha) that possessed a 1% resistant allele frequency at a cost of $500/ha, substantiating the cost effectiveness of the genotyping approaches to monitoring. 相似文献
994.
Mundy NI Badcock NS Hart T Scribner K Janssen K Nadeau NJ 《Science (New York, N.Y.)》2004,303(5665):1870-1873
A key question in evolutionary genetics is whether shared genetic mechanisms underlie the independent evolution of similar phenotypes across phylogenetically divergent lineages. Here we show that in two classic examples of melanic plumage polymorphisms in birds, lesser snow geese (Anser c. caerulescens) and arctic skuas (Stercorarius parasiticus), melanism is perfectly associated with variation in the melanocortin-1 receptor (MC1R) gene. In both species, the degree of melanism correlates with the number of copies of variant MC1R alleles. Phylogenetic reconstructions of variant MC1R alleles in geese and skuas show that melanism is a derived trait that evolved in the Pleistocene. 相似文献
995.
Dong Woo Chang Bora Kim Jae Hoon Shin Young Min Yun Jung Ho Je Yeu kuang Hwu Jung Hee Yoon Je Kyung Seong 《Journal of veterinary science (Suw?n-si, Korea)》2011,12(2):107-113
The X-ray synchrotron is quite different from conventional radiation sources. This technique may expand the capabilities of conventional radiology and be applied in novel manners for special cases. To evaluate the usefulness of X-ray synchrotron radiation systems for real time observations, mouse fetal skeleton development was monitored with a high resolution X-ray synchrotron. A non-monochromatized X-ray synchrotron (white beam, 5C1 beamline) was employed to observe the skeleton of mice under anesthesia at embryonic day (E)12, E14, E15, and E18. At the same time, conventional radiography and mammography were used to compare with X-ray synchrotron. After synchrotron radiation, each mouse was sacrificed and stained with Alizarin red S and Alcian blue to observe bony structures. Synchrotron radiation enabled us to view the mouse fetal skeleton beginning at gestation. Synchrotron radiation systems facilitate real time observations of the fetal skeleton with greater accuracy and magnification compared to mammography and conventional radiography. Our results show that X-ray synchrotron systems can be used to observe the fine structures of internal organs at high magnification. 相似文献
996.
Jae-Woo Choi Seung-Gun Chung Kie-Yong Cho Kyung-Youl Baek Seok-Won Hong Dong-Ju Kim Sang-Hyup Lee 《Water, air, and soil pollution》2012,223(3):1437-1441
This study investigated the encapsulation and photocatalysis of chlorophenol compounds in water using porphyrin-(polystyrene-b-2-dimethylaminoethyl acrylate) star polymer. The chloride ions generated during photocatalytic process were identified and
quantified. 2,4,6-Trichlorophenol, pentachlorophenol, and 2,4-dichlorophenol were satisfactorily decomposed in the photoreactor
using porphyrin-(polystyrene-b-2-dimethylaminoethyl acrylate) star polymer, with removal efficiencies of 2,454, 498, and 760 mg/g of porphyrin-(polystyrene-b-2-dimethylaminoethyl acrylate) star polymer. The half-life times reached around 30 min, with the exception of that for 2,4-dichlorophenol.
The star polymer-impregnated porphyrin is a promising photocatalyst for the removal of chlorophenols. 相似文献
997.
Jae Hong Kim 《Growth and change》2013,44(4):650-675
Although urban growth boundaries (UGBs) are increasingly used as a containment policy to promote contiguous and compact urban forms, little is known about how UGBs affect development within the designated area or how development is displaced to other cities. This study analyzes the UGB's containment and spillover effects, focusing on the case of the Portland metropolitan area where UGBs have long been implemented. This is accomplished by employing a spatial market disequilibrium framework in which explicit consideration is given to the containment and spillover processes when under the influences of UGBs. The findings suggest that UGBs can promote development within the boundaries, but that cooperation with neighboring municipalities is necessary to effectively attain the policy goals. 相似文献
998.
999.
SooHwan Kim Taehwan Oh Siyeon Yang Hyejean Cho Chanhee Chae 《Canadian journal of veterinary research》2021,85(1):77
The objective of this study was to evaluate the efficacy of a new Mycoplasma hyopneumoniae bacterin against a Korean M. hyopneumoniae challenge under experimental conditions. Fifteen pigs were allocated randomly into 3 groups (5 pigs per group) that were designated in 1 of 3 ways: vaccinated-challenged, unvaccinated-challenged, or unvaccinated-unchallenged. The pigs in the vaccinated-challenged group were immunized with an M. hyopneumoniae whole-cell bacterin at a 1.0 mL dose-level at 21 d old. At 42 d old (0 d post-challenge), the pigs in the vaccinated-challenged and unvaccinated-challenged groups were inoculated intranasally with a strain of Korean M. hyopneumoniae. Vaccinated-challenged pigs elicited a strong cell-mediated immunity as measured by M. hyopneumoniae-specific interferon-γ secreting cells when compared with unvaccinated-challenged pigs. Vaccination of pigs with this new M. hyopneumoniae bacterin reduced nasal shedding and lung lesions. The evaluated vaccine was therefore considered effective in controlling M. hyopneumoniae infection. 相似文献
1000.
Sung‐Eun Lee Byoung‐Ho Lee Won‐Sik Choi Byeoung‐Soo Park Jeong‐Gyu Kim Bruce C Campbell 《Pest management science》2001,57(6):548-553
The fumigant toxicity of various volatile constituents of essential oils extracted from sixteen Korean spices and medicinal plants towards the rice weevil, Sitophilus oryzae L (Coleoptera: Curculionidae), was determined. The most potent toxicity was found in the essential oil from Mentha arvensis L var piperascens (LC50 = 45.5 µl litre?1 air). GC–MS analysis of essential oil from M arvensis showed it to be rich in menthol (63.2%), menthone (13.1%) and limonene (1.5%), followed in abundance by β‐pinene (0.7%), α‐pinene (0.6%) and linalool (0.2%). Treatment of S oryzae with each of these terpenes showed menthone to be most active (LC50 = 12.7 µl litre?1 air) followed by linalool (LC50 = 39.2 µl litre?1 air) and α‐pinene (LC50 = 54.9 µl litre?1 air). Studies on inhibition of acetylcholinesterase activity of S oryzae showed menthone to have a nine‐fold lower inhibitory effect than menthol, despite menthone being 8.1‐fold more toxic than menthol to the rice weevil. Different modes of toxicity of these monoterpenes towards S oryzae are discussed. © 2001 Society of Chemical Industry 相似文献