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51.
V.B. Meacham BS 《Journal of Equine Veterinary Science》1984,4(5):210-214
Mineral metabolism in the equine is a complex process involving absorption sites and interactions between the minerals themselves and other compounds. Factors such as the digestibility of the minerals and the extent of the interactions all play an important role in the mineral amounts required in the diet.Inadequate levels of minerals in the diet can lead to physiological maladies such as HNS and Ricketts. A knowledge and understanding of mineral metabolism is essential to the success of equine management. 相似文献
52.
Mark P. Nasisse DVM Barbara J. Davis VMD James S. Guy DVM PhD Michael G. Davidson DVM Wendy Sussman BS 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1992,6(2):102-103
Feline herpesvirus 1 (FHV-1) is one of the most common viral infections of domestic cats worldwide, estimated to cause 50% of all respiratory infections in this species. Feline herpesvirus 1 is also an important ocular pathogen of cats, causing conjunctivitis, epithelial and stromal keratitis, symblepharon formation, keratocon-junctivitis sicca, and corneal sequestration. Despite the importance of this viral disease, major questions remain unanswered concerning the pathogenesis of its most important manifestation, the recrudescent infection. Although the taxonomic classification of FHV-1 as an alpha herpesvirus implies the ability of FHV-1 to establish neural latency, attempts at recovering the virus from the trigeminal ganglia of latently infected cats have typically yielded negative results. This failure has stimulated speculation that neural tissue is not an important site for latent FHV-1. However, in the most successful of such studies, FHV-1 was isolated from the trigeminal ganglia of 3 of 17 cats using an explant technique. In the present study, we describe the successful isolation of FHV-1 from the trigeminal ganglia of cats using a similar tissue culture method. 相似文献
53.
Sandra A. Loftus BA Jill M. Montplaisir BS Jing-wen Kuo MS Dale P. DeVore PhD 《Journal of Equine Veterinary Science》1988,8(2)
A standardized investigation was conducted to compare the biophysical properties of hyaluronate products used in the treatment of joint dysfunction in horses. Results showed that two of the five products, Hyvisc® and Hylartin®V, contained higher-weight molecular hyaluronate (greater than 1.5×106). Other investigations have shown that higher molecular weight hyaluronate is effective in providing physical resistance to shear, in stimulating endogenous hyaluronate synthesis, and in inhibiting excess cell proliferation which may be associated with synovial pannus formation. It is suggested that the therapeutic benefits of hyaluronate products may be dependent on the molecular size of the hyaluronate molecules. Higher molecular weight hyaluronate products would be expected to be more effective than lower molecular hyaluronate products in providing therapeutic benefits. 相似文献
54.
C. A. BLAZE BVSC DipiomateACVA R. E. HOLLAND DVM MS A. L. GRANT BS 《Veterinary surgery : VS》1988,17(3):155-159
Ten neonatal calves were anesthetized with xylazine and ketamine intramuscularly and breathed air spontaneously. Drug injection was repeated after 45 minutes. Each injection resulted in a rapid and sustained increase in respiratory rate, but arterial carbon dioxide tension (PaCO2) increased, indicating hypoventilation. Arterial hypoxemia, primarily caused by hypoventilation, developed within 15 minutes of each injection, but gradually disappeared. Acidemia was primarily respiratory in origin. Heart rate and arterial blood pressure decreased for the duration of anesthesia (90 minutes). This form of anesthesia is a satisfactory alternative to inhalation anesthesia of neonatal calves. 相似文献
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A recent study has suggested a central role for hyperactivated sperm motility in successful equine in vitro fertilization, as the highest apparent fertilization rates reported yet were obtained using exogenous stimulation of hyperactivated motility in sperm that had been incubated for capacitation. Hyperactivated motility has been studied intensively in other species, but little data are available in this area in the horse. Hyperactivated motility is associated with an influx of calcium from the extracellular space, and in other species this occurs because of an increase in intracellular pH during capacitation. Influx of calcium seems to trigger changes in flagellar function through calcium–calmodulin–calmodulin kinase-related effects on dynein function, but the exact mechanisms resulting in hyperactivated motility are still unclear. We have been exploring the physiology of hyperactivated motility in stallion spermatozoa and have found many of the mechanisms present in other species to be in place in the stallion. Further research is needed to determine why stallion spermatozoa seem to fail to undergo hyperactivation in response to capacitating environments that support this activity in other species. 相似文献
59.
Serum protein concentrations as predictors of serum immunoglobulin G concentration in neonatal foals
60.
Melinda H. MacDonald DVM PhD Anthony M. Tesch BS Hilary P. Benton PhD Neil H. Willits PhD 《Journal of Equine Veterinary Science》2002,22(1)
Objective: To characterize the impact of age, gender, location and individual animal variation on the composition of articular cartilage from the metacarpophalangeal joint of horses. Design: Cartilage specimens were obtained from the metacarpophalangeal joints of 28 male, female and castrated male horses ranging in age from one day to 27 years of age. Cartilage samples from the distal metacarpus, proximal first phalanx and proximal sesamoids were analyzed separately. Chondrocyte number, DNA content, proteoglycan concentration and total collagen content were determined for each animal and joint location. Results: Age and joint location had a significant effect on chondrocyte number and DNA content with higher cell counts and DNA content detected in cartilage from the youngest age groups and in cartilage from the metacarpus and proximal sesamoids. The influence of age on chondrocyte numbers was not significant in horses over two years of age. Both age and joint location also influenced total proteoglycan and collagen content. Lower proteoglycan and collagen concentrations were detected in younger horses, and cartilage from the metacarpus had lower proteoglycan and collagen concentrations than that from other joint locations. Gender did not appear to influence chondrocyte number or matrix content of equine articular cartilage. However, there was significant residual variation in cellularity, proteoglycan levels and collagen content between individual animals that could not be explained by the signalment factors considered in this study. Conclusions: Future studies examining equine articular cartilage should avoid direct morphologic comparisons between animals of different ages, and any comparisons made between individuals should be interpreted cautiously. In addition, in vitro tissue culture models should avoid the use of cartilage pooled from different animals or from different locations within the same joint. 相似文献