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243.
The mantle flow field beneath western North America 总被引:3,自引:0,他引:3
Although motions at the surface of tectonic plates are well determined, the accompanying horizontal mantle flow is not. We have combined observations of surface deformation and upper mantle seismic anisotropy to estimate this flow field for western North America. We find that the mantle velocity is 5.5 +/- 1.5 centimeters per year due east in a hot spot reference frame, nearly opposite to the direction of North American plate motion (west-southwest). The flow is only weakly coupled to the motion of the surface plate, producing a small drag force. This flow field is probably due to heterogeneity in mantle density associated with the former Farallon oceanic plate beneath North America. 相似文献
244.
The aim of the study was to assess whether the hair of stray and domestic dogs in Egypt was contaminated with the eggs of the zoonotic parasite Toxocara canis, and also to identify risk factors for T. canis for contamination. Paired samples of hair and feces were collected from 53 stray and 47 domestic dogs, and hair samples were obtained from a further 11 stray and 9 domestic dogs. All samples were examined to identify T. canis eggs and, if eggs were found, their maturation stage. Eggs were identified in 26.6% of stray and 10.7% of domestic dog's hair samples. A significantly increased risk of embryonated T. canis eggs in hair samples was found in stray dogs (p=0.04), stray dogs had 3.18 (95% CI: 1.04-9.74) times the odds of having T. canis eggs present compared with domestic dogs. There was also a significant difference (p=0.02) between the mean quantity of eggs per gram in stray (77.6±6.54) and domestic (48.7±6.65) dog's hair. Fecal examination found a T. canis egg prevalence of 35.8% and 21.3% in stray and domestic dogs, respectively. As no domestic dogs which were positive from hair samples had negative fecal samples, this indicates that the presence of T. canis eggs in hair is probably due to self contamination. Two stray dogs had positive hair samples but negative fecal samples indicating that contamination may also be environmental. As both non-embryonated and embryonated T. canis eggs were found in the hair of domestic dogs, direct contact with dogs may be a potential risk factor for transmission of T. canis eggs to humans. 相似文献
245.
Contamination of eggs by Salmonella Enteritidis has been a prominent cause of human illness for several decades and is the focus of a recently implemented national regulatory plan for egg-producing flocks in the United States. Salmonella Heidelberg has also been identified as an egg-transmitted pathogen. The deposition of Salmonella strains inside eggs is a consequence of reproductive tract colonization in infected laying hens, but prior research has not determined the relationship between the numbers of Salmonella that colonize reproductive organs and the associated frequency of egg contamination. In the present study, groups of laying hens in two trials were experimentally infected with large oral doses of strains of Salmonella Enteritidis (phage type 13a), Salmonella Heidelberg, or Salmonella Hadar. Reproductive tissues of selected hens were cultured to detect and enumerate Salmonella at 5 days postinoculation, and the interior contents of eggs laid between 6 and 25 days postinoculation were tested for contamination. Significantly more internally contaminated eggs were laid by hens infected with Salmonella Enteritidis (3.58%) than with strains of either Salmonella Heidelberg (0.47%) or Salmonella Hadar (0%). However, no significant differences were observed between Salmonella strains in either isolation frequency or the number of colony-forming units (CFU) isolated from ovaries or oviducts. Salmonella isolation frequencies ranged from 20.8% to 41.7% for ovaries and from 8.3% to 33.3% for oviducts. Mean Salmonella colonization levels ranged from 0.10 to 0.51 log CFU/g for ovaries and from 0.25 to 0.46 log CFU/g for oviducts. Although parallel rank-orders were observed for Salmonella enumeration (in both ovaries and oviducts) and egg contamination frequency, a statistically significant relationship could not be established between these two parameters of infection. 相似文献
246.
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer 总被引:195,自引:0,他引:195
D J Slamon W Godolphin L A Jones J A Holt S G Wong D E Keith W J Levin S G Stuart J Udove A Ullrich 《Science (New York, N.Y.)》1989,244(4905):707-712
Carcinoma of the breast and ovary account for one-third of all cancers occurring in women and together are responsible for approximately one-quarter of cancer-related deaths in females. The HER-2/neu proto-oncogene is amplified in 25 to 30 percent of human primary breast cancers and this alteration is associated with disease behavior. In this report, several similarities were found in the biology of HER-2/neu in breast and ovarian cancer, including a similar incidence of amplification, a direct correlation between amplification and over-expression, evidence of tumors in which overexpression occurs without amplification, and the association between gene alteration and clinical outcome. A comprehensive study of the gene and its products (RNA and protein) was simultaneously performed on a large number of both tumor types. This analysis identified several potential shortcomings of the various methods used to evaluate HER-2/neu in these diseases (Southern, Northern, and Western blots, and immunohistochemistry) and provided information regarding considerations that should be addressed when studying a gene or gene product in human tissue. The data presented further support the concept that the HER-2/neu gene may be involved in the pathogenesis of some human cancers. 相似文献
247.
Holt D 《Science (New York, N.Y.)》1987,237(4821):1401-1402
248.
The aim of this study was to determine the effect of whole-tree harvesting (WTH) on the growth of Scots pine (Pinus sylvestris L.) and Norway spruce (Picea abies (L.) Karst.) as compared to conventional stem harvesting (CH) over 10 and 20 years. Compensatory (WTH + CoF) and normal nitrogen-based (CH + F or WTH + F) fertilisation were also studied. A series of 22 field experiments were established during 1977-1987, representing a range of site types and climatic conditions in Finland, Norway and Sweden. The treatments were performed at the time of establishment and were repeated after 10-13 years at 11 experimental sites. Seven experiments were followed for 25 years.Volume increment was on average significantly lower after WTH than after CH in both 10-year periods in the spruce stands. In the pine stands thinned only once, the WTH induced growth reduction was significant during the second 10-year period, indicating a long-term response.Volume increment of pine stands was 4 and 8% and that of spruce stands 5 and 13% lower on the WTH plots than on CH during the first and the second 10-year period, respectively. For the second 10-year period the relative volume increment of the whole-tree harvested plots tended to be negatively correlated with the amount of logging residue. Accordingly, the relative volume increment decreased more, the more logging residue was harvested, stressing the importance of developing methods for leaving the nutrient-rich needles on site.If nutrient (N, P, K) losses with the removed logging residues were compensated with fertiliser (WTH + CoF), the volume increment was equal to that in the CH plots. Nitrogen (150-180 kg ha−1) or N + P fertilisation increased tree growth in all experiments except in one very productive spruce stand. Pine stands fertilised only once had a normal positive growth response during the first 10-year period, on average 13 m3 ha−1, followed by a negative response of 5 m3 ha−1 during the second 10-year period. The fertilisation effect of WTH + F and WTH + CoF on basal area increment was both smaller and shorter than with CH + F. 相似文献
249.
Kerry L. Howell Rebecca Holt Inés Pulido Endrino Heather Stewart 《Biological conservation》2011,144(11):2656-2665
Internationally there is political momentum to establish networks of marine protected areas for the conservation of threatened species and habitats. Practical implementation of such networks requires an understanding of the distribution of these species and habitats. Predictive modelling provides a method by which continuous distribution maps can be produced from limited sample data. This method is particularly useful in the deep sea where a number of biological communities have been identified as vulnerable ‘habitats’, including Lophelia pertusa reefs. Recent modelling efforts have focused on predicting the distribution of this species. However the species is widely distributed where as reef habitat is not. This study uses Maxent predictive modelling to investigate whether the distribution of the species acts as a suitable proxy for the reef habitat. Models of both species and habitat distribution across Hatton Bank and George Bligh Bank are constructed using multibeam bathymetry, interpreted substrate and geomorphology layers, and derived layers of bathymetric position index (BPI), rugosity, slope and aspect. Species and reef presence records were obtained from video observations. For both models performance is fair to excellent assessed using AUC and additional threshold dependant metrics. 7.17% of the study area is predicted as highly suitable for the species presence while only 0.56% is suitable for reef presence, using the sensitivity–specificity sum maximisation approach to determine the appropriate threshold. Substrate is the most important variable in the both models followed by geomorphology in the RD model and fine scale BPI in the SD model. The difference in the distributions of reef and species suggest that mapping efforts should focus on the habitat rather than the species at fine (100 m) scales. 相似文献
250.