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Albarède F 《Science (New York, N.Y.)》2005,310(5755):1777-1778
105.
Murphy WJ Larkin DM Everts-van der Wind A Bourque G Tesler G Auvil L Beever JE Chowdhary BP Galibert F Gatzke L Hitte C Meyers SN Milan D Ostrander EA Pape G Parker HG Raudsepp T Rogatcheva MB Schook LB Skow LC Welge M Womack JE O'brien SJ Pevzner PA Lewin HA 《Science (New York, N.Y.)》2005,309(5734):613-617
The genome organizations of eight phylogenetically distinct species from five mammalian orders were compared in order to address fundamental questions relating to mammalian chromosomal evolution. Rates of chromosome evolution within mammalian orders were found to increase since the Cretaceous-Tertiary boundary. Nearly 20% of chromosome breakpoint regions were reused during mammalian evolution; these reuse sites are also enriched for centromeres. Analysis of gene content in and around evolutionary breakpoint regions revealed increased gene density relative to the genome-wide average. We found that segmental duplications populate the majority of primate-specific breakpoints and often flank inverted chromosome segments, implicating their role in chromosomal rearrangement. 相似文献
106.
Edery P Marcaillou C Sahbatou M Labalme A Chastang J Touraine R Tubacher E Senni F Bober MB Nampoothiri S Jouk PS Steichen E Berland S Toutain A Wise CA Sanlaville D Rousseau F Clerget-Darpoux F Leutenegger AL 《Science (New York, N.Y.)》2011,332(6026):240-243
The spliceosome, a ribonucleoprotein complex that includes proteins and small nuclear RNAs (snRNAs), catalyzes RNA splicing through intron excision and exon ligation to produce mature messenger RNAs, which, in turn serve as templates for protein translation. We identified four point mutations in the U4atac snRNA component of the minor spliceosome in patients with brain and bone malformations and unexplained postnatal death [microcephalic osteodysplastic primordial dwarfism type 1 (MOPD 1) or Taybi-Linder syndrome (TALS); Mendelian Inheritance in Man ID no. 210710]. Expression of a subgroup of genes, possibly linked to the disease phenotype, and minor intron splicing were affected in cell lines derived from TALS patients. Our findings demonstrate a crucial role of the minor spliceosome component U4atac snRNA in early human development and postnatal survival. 相似文献
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Full disk images of Mars have been obtained with the use of the Very Large Array (VLA) to map the radar reflected flux density. The transmitter system was the 70-m antenna of the Deep Space Network at Goldstone, California. The surface of Mars was illuminated with continuous wave radiation at a wavelength of 3,5 cm. The reflected energy was mapped in individual 12-minute snapshots with the VLA in its largest configuration; fringe spacings as small as 67 km were obtained. The images reveal near-surface features including a region in the Tharsis volcano area, over 2000 km in east-west extent, that displayed no echo to the very low level of the radar system noise. The feature, called Stealth, is interpreted as a deposit of dust or ash with a density less than about 0.5 gram per cubic centimeter and free of rocks larger than 1 cm across. The deposit must be several meters thick and may be much deeper. The strongest reflecting geological feature was the south polar ice cap, which was reduced in size to the residual south polar ice cap at the season of observation. The cap image is interpreted as arising from nearly pure CO(2) or H(2)O ice with a small amount of martian dust (less than 2 percent by volume) and a depth greater than 2 to 5 m. Only one anomalous reflecting feature was identified outside of the Tharsis region, although the Elysium region was poorly sampled in this experiment and the north pole was not visible from Earth. 相似文献
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Marilyn Holly Carla A. Kirts Yvonne Everett Jan L. Flora David O. Hansen Cornelia Butler Flora John A. Hayward David Haenke Alessandro Bonanno 《Agriculture and Human Values》1988,5(4):57-78
Marilyn Holly is an Associate Professor of Philosophy at the University of Florida. Her special interests include political philosophy, ethics and ecology, Jungian thought, and Native American spirituality in its relation to the environment. She is currently at work on a monograph-length piece on the latter topic. She has taught an undergraduate course in ethics and ecology, and plans to do so again. The following essay emerged from her search for a suitable text for such a course. 相似文献
109.
Changes in land-uses, fire regimes, and climate are expected to promote savanna expansion in the Amazon Basin, but most studies that come to this conclusion fail to define “savanna” clearly or imply that natural savannas of native species will spread at the expense of forest. Given their different conservation values, we sought to differentiate between species-diverse natural savannas and other types of fire-maintained grass-dominated vegetation that replaced tropical forests between 1986 and 2005 in 22,500 km2 of eastern lowland Bolivia. Analysis of Landsat TM and CBERS-2 satellite imagery revealed that, in addition to 1200 km2 (7.1%) of deforestation for agriculture and planted pastures, 1420 km2 (8.4%) of forest was replaced by derived savannas. Sampling in 2008 showed that natural savannas differed from forest-replacing derived savannas floristically, in soil fertility, and in fuel loads. Natural savannas typically occurred on sandy, acidic, nutrient-poor soils whereas most derived savannas were on comparatively fertile soils. Fuel loads in derived savannas were twice those of natural savannas. Natural savannas supported a diversity of grass species, whereas derived savannas were usually dominated by Guadua paniculata (native bamboo), Urochloa spp. (exotic forages), Imperata brasiliensis (native invasive), Digitaria insularis (native ruderal), or the native fire-adapted herb Hyptis suaveolens (Lamiaceae). Trees in derived savannas were forest species (e.g., Anadenanthera colubrina) and fire-tolerant palms (Attalea spp.), not thick-barked species characteristic of savanna environments (e.g., Curatella americana). In addressing tropical vegetation transitions it is clearly important to distinguish between native species-diverse ecosystems and novel derived vegetation of similar structure. 相似文献
110.
Francis Zvomuya Francis J. Larney Walter D. Willms Ryan K. Beck Andrew F. Olson 《Strength and Conditioning Journal》2011,64(4):375-383
Landspraying while drilling (LWD) is an approved disposal method for water-based drilling mud (WBM) systems in western Canada. The mud is applied either on cultivated land, where it is incorporated by cultivation, or on vegetated land where it is not incorporated. This study examined the effects of summer WBM application (0, 15, 20, 40, and 80 m3 · ha?1) on native vegetation properties. Our results indicated that LWD increased bare ground but decreased lichen cover at the 80 m3 · ha?1 rate relative to the untreated control. Nitrogen (N), sulfur (S), and magnesium (Mg) concentrations in aboveground plant tissue increased with increasing LWD rate in samples taken 45 d after WBM application, but these differences disappeared 1 yr after treatment. Increase in tissue concentration of phosphorus (P) with LWD rate, however, was only detected 3 yr after LWD. Nonetheless, these changes in tissue chemistry were not associated with significant changes in biomass yield or species composition. Overall, our results suggest that single WBM applications at rates (≤ 20 m3 · ha?1) commonly used in western Canada, if properly managed, are unlikely to adversely affect native prairie vegetation. 相似文献