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91.
92.
H A Garverick M F Smith R G Elmore G L Morehouse L S Agudo W L Zahler 《Journal of animal science》1985,61(1):216-223
Changes and interrelationships among the cellular mechanisms that may regulate luteal progesterone synthesis during the bovine estrous cycle were studied. Corpora lutea (CL) were enucleated from 30 cows via a transvaginal incision on d 4, 7, 10, 13, 16 and 19 following estrus (estrus = d 0). Mean corpus luteum weight, and luteal progesterone and plasma progesterone concentrations increased (P less than .05) from d 4 to 7 or 10, and declined following luteal regression (d 19). Unoccupied LH receptor (UOR) concentrations increased (P less than .05) more than fourfold from d 4 (38 fmol/mg protein) to d 16 (173 fmol/mg protein) before declining (P less than .05) by d 19 (30 fmol/mg protein). The dissociation constant for UOR concentrations increased (P less than .05) during the estrous cycle. Concentrations of occupied LH receptors (OR) were less (P less than .05) on d 7 than other days; however, the total number of OR/CL increased fourfold from d 4 (47 fmol/CL) to d 10 (221 fmol/CL) and remained similar thereafter. Basal adenylate cyclase, LH-activated adenylate cyclase, and Gpp(NH)p-activated adenylate cyclase activities were greatest (P less than .05) on d 7 to 16 as compared with d 4 and 19. Luteinizing hormone stimulated (P less than .05) adenylate cyclase activity relative to basal activity on d 7, 10, 13, and 16; whereas, Gpp(NH)p stimulated (P less than .05) adenylate cyclase activity relative to basal activity at each period. Phosphodiesterase was 46% greater on d 19 as compared with d 4.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
93.
Jerome CJ Fryer 《Journal of circadian rhythms》2009,7(1):1-5
The nature of atonia in sleep continues to be enigmatic. This article discusses a new hypothesis for complete core muscle relaxation in REM sleep, suggesting a bottom-up recuperative perspective. That is, does the atonia in REM sleep provide a utility to help restore the mechanobiology and respective diurnal intervertebral disc hydraulic loss? By combining the effects of gravity with current compressive concepts in spinal stability, this article looks at vertebral approximation as a deleterious experience with an intrinsic biological need to keep vertebrae separated. Methods using polysomnography and recumbent MRI are discussed. 相似文献
94.
A 9‐year‐old Thoroughbred gelding was presented for swelling over the left neck and inappetence. There was recent history of intramuscular administration of flunixin meglumine into the left neck. On examination, there was evidence of focal myositis, anaemia, haemolysis and pigmenturia. Culture of aspirated fluid from the left side of the neck produced a heavy growth of a Clostridium species. Complications of infection included haemolytic anaemia, hepatopathy, osteitis and transient hypertrophic cardiomyopathy. Treatment included intravenous fluid therapy, antibiotics, anti‐inflammatory drugs, blood transfusion and surgical debridement. There was complete resolution of clinical, haematological, biochemical and echocardiographic abnormalities, and the horse returned to ridden work. This report highlights the complications that can arise from clostridial myonecrosis, including the effect on the myocardium. 相似文献
95.
Gastric dilatation-volvulus (GDV) is a disease in which there is gross distension of the stomach with fluid or gas and gastric malpositioning. It causes pathology of multiple organ systems and is rapidly fatal. It is common in large- and giant-breed dogs. The disease appears to have a familial predisposition. Thoracic depth/width ratio also appears to predispose dogs to GDV. Implicated dietary factors include dietary particle size, frequency of feeding, speed of eating, aerophagia and an elevated feed bowl. A fearful temperament and stressful events may also predispose dogs to GDV. Abdominal distension, non-productive retching, restlessness, signs of shock, tachypnoea and dyspnoea are possible clinical signs. Initial treatment includes treatment of shock and gastric decompression. Surgical treatment should be performed promptly. There are no studies comparing the use of different anaesthetic agents in the anaesthetic management of GDV. Pre-medication with an opioid/benzodiazepine combination has been recommended. Induction agents that cause minimal cardiovascular changes such as opioids, neuroactive steroidal agents and etomidate are recommended. Anaesthesia should be maintained with an inhalational agent. Surgical therapy involves decompression, correction of gastric malpositioning, debridement of necrotic tissue, and gastropexy. Options for gastropexy include incisional, tube, circumcostal, belt-loop, incorporating, and laparoscopic gastropexy. Expected mortality with surgical therapy is 15–24%. Prognostic factors include mental status on presentation, presence of gastric necrosis, presence of cardiac arrhythmia and plasma lactate levels. Prophylactic gastropexy should be considered in dogs identified as being at high risk. 相似文献
96.
Double-outlet right ventricle in a 10-month-old Friesian filly 总被引:1,自引:1,他引:0
LC Fennell S Church D Tyrell G Forbes JA Charles C McCowan CJ Savage 《Australian veterinary journal》2009,87(5):204-209
A 10-month-old Friesian filly had a presentation that was consistent with chronic left- and right-sided congestive heart failure. Clinical pathology findings included abnormal haematological and biochemical variables, abnormal blood gas values and increased serum concentration of cardiac troponin I. Echocardiography revealed cardiac chamber dilation and dextropositioning of the aorta. Radiography revealed a generally enlarged heart and pulmonary interstitial infiltration. These findings were supported at necropsy and the diagnosis of double-outlet right ventricle was confirmed. The pathological changes and physiological responses subsequent to double-outlet right ventricle have not previously been described in detail in horses. Clinical progression closely resembles that seen in humans, in whom antemortem diagnosis relies on echocardiography. In horses, complex cardiac disease presents a diagnostic challenge to the clinician. Appropriate therapy must be based on an accurate diagnosis. 相似文献
97.
Bob Thoolen Fiebo J.W. ten Kate Paul J. van Diest David E. Malarkey Susan A. Elmore Robert R. Maronpot 《Journal of toxicologic pathology》2012,25(3):189-199
In this comparative review, histomorphological features of common nonneoplastic and
neoplastic hepatocyte lesions of rats and humans are examined using H&E-stained
slides. The morphological similarities and differences of both neoplastic (hepatocellular
carcinoma and hepatocellular adenoma) and presumptive preneoplastic lesions (large and
small cell change in humans and foci of cellular alteration in rats) are presented and
discussed. There are major similarities in the diagnostic features, growth patterns and
behavior of both rat and human hepatocellular proliferative lesions and in the process of
hepatocarcinogenesis. Further study of presumptive preneoplastic lesions in humans and
rats should help to further define their role in progression to hepatocellular neoplasia
in both species. 相似文献
98.
Summary Soybean [Glycine max (L.) Merr.] producers in the Great Plains region usually employ either a seasonal soil water balance approach, or a growth stage sensitivity approach, relative to scheduling sprinkler irrigation events. We conducted an empirical evaluation of the response of six soybean cultivars to three irrigation strategies. One was an irrigation scheduling (IS) system based solely on maintaining a soil water content in the root zone between 50% and 80% of the total plant available soil water capacity. The other two strategies involved the same depletion criterion for triggering irrigation events, except that the first irrigation was intentionally delayed until the flowering (FL) stage, or the mid-pod elongation (PD) stage. The total water amount applied during each season was approximately similar for the IS, FL, and PD strategies. Thus, the primary difference among the three strategies was the time frame during which irrigation events were scheduled. In the 1983 test, the yields attained in the IS, FL, and PD treatments were not significantly different from each other (i.e. 4.08, 4.08, and 4.04 Mg/ha, respectively), and were nearly double the yield obtained in the nonirrigated (NI) check treatment (2.29 Mg/ha). In the 1984 test, the yields of the IS, FL, and PD treatments were again not significantly different (2.02, 2.05, and 2.22 Mg/ha, respectively). However, the 1984 yield response to irrigation was also not significant relative to the NI check (1.90 Mg/ha), primarily because of low plant populations and a shorter growing season. Thus, this two-year experiment indicated that delaying irrigation until the FL or the PD stages of soybean reproductive development could be just as effective (i.e. 1983 data), or at least no more ineffective (i.e. 1984 data), in enhancing soybean yield compared to the IS strategy (Fig. 1). The soil water balance and soybean growth stage sensitivity approaches, when combined, could thus constitute an effective strategy of soybean sprinkler irrigation management in the Great Plains region.Contribution of the Department of Agronomy and Department of Agricultural Engineering, University of Nebraska, Lincoln, NE 68583. Published as Paper no. 8461, Journal Series, Nebraska Agric. Exp. Stn. Project no. 12-091. Research partially funded by grants received from the Nebraska Soybean Development, Utilization, and Marketing Board 相似文献
99.
Identification of ectopic ovotestis in a dog with XX ovotesticular,SRY‐negative,disorder of sexual development
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M Diel de Amorim A Lerer T Durzi RA Foster CJ Gartley 《Reproduction in domestic animals》2018,53(3):822-825
A 1‐year‐old, previously spayed phenotypic female Poodle/Soft‐coated Wheaten Terrier (Whoodle) cross was presented for a suspected ovarian remnant. Serum luteinizing hormone (LH) concentration was below the detection limit (<1 ng/ml Witness® LH), and serum progesterone concentration was elevated in the chemiluminescence immunoassay (CLIA; 20 ng/ml), consistent with dioestrus and presence of ovarian tissue. Transabdominal ultrasound revealed a retroperitoneal soft tissue structure suspected to be a gonad. On exploratory laparotomy, a gonad was removed from the cranial retroperitoneum, cranial to the right kidney, after ligation of its primary blood supply. Histological examination proved the gonad to be an ovotestis. Subsequent cytogenetics revealed a 78 XX karyotype, thus confirming the diagnosis of ectopic ovotestis in a XX ovotesticular, SRY‐negative, disorder of sexual development in a dog. 相似文献
100.