Polychlorinated Dibenzo-p-dioxins and Dibenzofurans in Sediments from Siskiwit Lake, Isle Royale

Polychlorinated dibenzo-p-dioxins and dibenzofurans were found in sediment from Siskiwit Lake on Isle Royale, Lake Superior, a location which can receive only atmospheric inputs. The source of these compounds is the atmospheric transport of dioxins and furans formed by combustion of domestic and chemical waste.     

Scientific communication and national security in 1984

The federal government's concern about maintaining the lead of the United States over the Soviet Union and its allies in militarily critical technology has led it to attempt to control unwanted technology transfer. Its attempts have extended to control of open scientific communication as well as the transfer of physical devices and blueprints. In 1982, the Corson Panel (an independent ad hoc committee) reviewed the evidence on the costs and benefits of controls and suggested guiding principles for government policy. This article examines the major policy developments since the Corson Panel completed its work. The stringency and the reach of government restrictions, either proposed or in force, go considerably beyond the panel's recommendations.     

Exencephaly in chicken‐pheasant hybrids

1. The incidence of exencephaly was investigated in chicken‐pheasant hybrids.

2. With the pheasant as sire, fertility was 7.lb6%, but with the fowl it was 19.lb5%; hatchability of fertile eggs, however, was similar, 42% and 41% respectively.

3. Only one exencephalic hybrid was obtained when the sire was the pheasant but 70 were noted when the fowl was sire. The incidence of this malformation in hatched chicks was 12 times more in crosses with the fowl as sire than in the reverse cross.

4. The frequency of exencephaly was greater with Rhode Island Red, Barred Leghorn or White Leghorn roosters than with Columbian Rock roosters.     

Responses of immune and nonimmune adult rhesus macaques (Macaca mulatta) to adenovirus SV-20.

Adenovirus SV-20 (ASV-20) was inoculated subcutaneously into adult rhesus macaques (Macaca mulatta), and various immunologic parameters were studied. Similar changes were observed in macaques that had anti-ASV-20 serum-neutralizing antibodies prior to inoculation and in those lacking detectable antibodies. There were absolute decreases in numbers of peripheral blood lymphocytes (PBL), erythrocyte-rosetting lymphocytes, complement-receptor lymphocytes, and Fc-receptor lymphocytes. These changes were most significant (P less than 0.05) on postinoculation days (PID) 3 and 7. Mitogenic responsiveness to concanavalin A, phytohemagglutinin, and pokeweed mitogen in cultured PBL from immune and nonimmune macaques was depressed on PID 3, 7, and 14. Ultraviolet-inactivated ASV-20 caused moderate suppression of phytohemagglutinin-induced mitogenesis when viral particles and lectin were added simultaneously to PBL cultures. Plasma cortisol (hydrocortisone) values were not significantly altered following inoculation of ASV-20. High titers of anti-ASV-20 antibody developed by PID 7 in nonimmune macaques, and previously immune macaques showed a booster effect in the same time period. Antibody titers were still increased 120 days after inoculation. There was no clinical evidence of an adverse effect of ASV-20 infection in these macaques.