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51.
Objective To compare the efficacy of moxidectin to ivermectin, oxibendazole and morantel against some gastrointestinal nematodes in horses.
Design Faecal egg count reduction after treatment.
Procedure A farm was selected where the population of small strongyles in horses was known to be resistant to oxibendazole. Horses were allocated to treatment groups based on faecal egg counts. After treatment, faecal samples were taken up to 109 days after treatment and faecal egg counts estimated. Faecal cultures were used to estimate the contribution of small and large strongyles to the faecal egg counts at each sampling.
Results Moxidectin (0.4 mg/kg) suppressed faecal egg counts for 109 days after treatment in most horses compared to 40 days with ivermectin (0.2 mg/kg), 13 days with morantel (9.4 mg/kg) and less than 13 days with oxibendazole (10 mg/kg). Most of the faecal egg count was attributable to small strongyles based on faecal culture, although Strongylus vulgaris was present in some samples in low numbers. Oxibendazole resistance in small strongyles was confirmed and a less than expected efficacy of morantel was also seen.
Conclusion Moxidectin was highly effective in reducing faecal egg counts after treatment for at least 12 weeks and up to 16 weeks in most horses. These horses were infected with a population of small strongyles known to be resistant to oxibendazole and possibly morantel. The duration of the reduction in faecal egg counts after treatment with moxidectin (0.4 mg/kg) was at least twice that of ivermectin (0.2 mg/kg) and greater than four times that for morantel and oxibendazole. 相似文献
Design Faecal egg count reduction after treatment.
Procedure A farm was selected where the population of small strongyles in horses was known to be resistant to oxibendazole. Horses were allocated to treatment groups based on faecal egg counts. After treatment, faecal samples were taken up to 109 days after treatment and faecal egg counts estimated. Faecal cultures were used to estimate the contribution of small and large strongyles to the faecal egg counts at each sampling.
Results Moxidectin (0.4 mg/kg) suppressed faecal egg counts for 109 days after treatment in most horses compared to 40 days with ivermectin (0.2 mg/kg), 13 days with morantel (9.4 mg/kg) and less than 13 days with oxibendazole (10 mg/kg). Most of the faecal egg count was attributable to small strongyles based on faecal culture, although Strongylus vulgaris was present in some samples in low numbers. Oxibendazole resistance in small strongyles was confirmed and a less than expected efficacy of morantel was also seen.
Conclusion Moxidectin was highly effective in reducing faecal egg counts after treatment for at least 12 weeks and up to 16 weeks in most horses. These horses were infected with a population of small strongyles known to be resistant to oxibendazole and possibly morantel. The duration of the reduction in faecal egg counts after treatment with moxidectin (0.4 mg/kg) was at least twice that of ivermectin (0.2 mg/kg) and greater than four times that for morantel and oxibendazole. 相似文献
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NJ Kannegieter KL Schaaf DK Lovell CD Simon BM Stone 《Australian veterinary journal》2010,88(4):132-136
We describe a fibrosarcoma in a 12-year-old Quarterhorse × Arabian gelding as a sequela to equine influenza vaccination. Shortly after the second vaccination, swelling at the site was noticed by the owner and it continued to increase in size over the following 6 months. Biopsy of the mass indicated a fibrosarcoma had developed at the vaccination site. It was approximately 20 cm in diameter and elevated well above the level of the skin. There was no clinical evidence of metastases to the lungs or local lymph nodes. Surgical resection of the mass was performed and the wound healed by first and second intention. Histopathological examination and immunohistochemical staining confirmed a myofibroblastic fibrosarcoma with multifocal osseous metaplasia. To the authors' knowledge, this is the first equine case of a vaccine-associated fibrosarcoma. 相似文献
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H Lomander H Gustafsson J Frössling KL Ingvartsen T Larsen C Svensson 《Reproduction in domestic animals》2012,47(6):988-994
The aim of this field study was to evaluate the effect of supplemental feeding with glycerol (GLY) or propylene glycol (PG) during early lactation on the fertility of Swedish dairy cows. Within 17 commercial dairy herds, 798 cows were randomized to three groups that were daily fed supplements with 450 g GLY, 300 g PG or nothing (control, C). The supplements were given twice daily during 0–21 days in milk as a top dress on concentrates. Data on calving date, insemination dates, gynaecological examinations, as well as breed, parity and monthly milk yield were collected. From a subset of 308 cows in seven herds, milk samples for progesterone analysis were taken twice weekly and used to determine the time for onset of luteal activity. The effects of supplements on the intervals from calving to first luteal activity (FLA), first AI (FAI) and conception (CON), respectively, were analysed using semi‐parametric survival models (Cox proportional hazards models) controlling for the effect of parity, breed, calving season, milk yield and the clustering effect of herd. There was no difference in time to FLA between the cows in group C and in group GLY or PG. No differences in time to FAI or in time to CON were found between cows in group PG and group C. However, cows in the GLY group tended to get their FAI later compared with cows in the control group but without at subsequent delaying of time to CON. 相似文献
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KL Goularte EM Madeira CER Ferreira EH Duval AD Vieira RG Mondadori T Lucia Jr 《Reproduction in domestic animals》2015,50(6):972-979
Bull semen production centres (SPC) generally present satisfactory quality control for sperm processing, but non‐standardized hygiene procedures. This study describes a Hazard Analysis and Critical Control Points (HACCP) system developed for bull SPC and subsequently implemented in a commercial SPC. After the identification of hazards at each step of semen processing and the determination of their risk and severity, monitoring and corrective procedures were designed to assess the system's efficiency. The HACCP system identified six microbiological hazards, 10 physical hazards, four chemical hazards and three critical control points. After the establishment of Good Processing Practices, Standard Operating Procedures and Standard Sanitizing Operating Procedures, the system was validated through an audit, to identify eventual failures and to define measures to correct them. 相似文献
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