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91.
92.
Blake A. Barbaree Matthew E. Reiter Catherine M. Hickey Nathan K. Elliott Danica Schaffer-Smith Mark D. Reynolds Gary W. Page 《Landscape Ecology》2018,33(5):829-844
Context
Animal movements are inherently linked to landscape structure. Understanding this relationship for highly-mobile species requires documenting their responses to spatiotemporal variability of resources. To that end, characterizing movement behaviors and resource distributions using the principles of habitat connectivity facilitates coordinated landscape planning efforts within highly modified landscapes.Objectives and methods
We tracked locations and movements for 156 dunlin (Calidris alpina) and 109 long-billed dowitchers (Limnodromus scolopaceus) overwintering in two regions with distinct water distributions in California’s Central Valley. We then compared residency rates, functional connectivity to other regions, and associations between movement distances and average habitat availability and structural connectivity of habitat at multiple temporal and spatial scales.Results
A widespread yet highly variable regional water distribution was associated with lower residency rates and substantially higher functional connectivity to nearby regions when compared to a stable regional water distribution characterized by a large, contiguous wetland complex. Longer movements were associated with decreasing average availability and spatial aggregation of surface water. Movement models suggested shorebirds primarily responded to habitat availability at smaller scales (<?10 km) and structural connectivity at larger scales (≥?10 km).Conclusions
Differences in movement behaviors suggested that wintering shorebirds will avoid long distance movements and remain resident within a wetland region when possible. Conservation and management efforts should reliably flood individual wetlands and agricultural lands from November to April and prioritize locations that maximize structural wetland connectivity and limit spatiotemporal variability of surface water throughout the Central Valley.93.
Acylamidase enzymes induced in the soil fungus Fusarium oxysporum Schlecht. by 3′,4′-dichloropropionanilide (propanil) and p-chlorophenyl methylcarbamate (PPG-124) were characterized according to pH optima, substrate specificity, specific activity, and sensitivity to various inhibitors. Both propanil- and PPG-124-induced enzymes were separated by ultrafiltration into >100,000 and >50,000 MW fractions. Both unique and similar characteristics were observed with the various enzyme preparations. Experimental parameters examined failed to unequivocally demonstrate whether any of the amidases induced were identical. Instead, the results indicated the possible presence of different amidases. 相似文献
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96.
Multi-dose vaccinators have been in use for many years to vaccinate livestock. A number of needle-free vaccinators that use compressed gas to drive the vaccine through intact skin have been recently introduced to the market. We recently examined the efficacy of a needle-free vaccinator to induce antibodies to tetanus toxoid in sheep. The result indicates that needle-free vaccination can stimulate antibody responses comparable to conventional needle vaccination. 相似文献
97.
Brian J. TORNABENE Erica J. CRESPI Creagh W. BREUNER Blake R. HOSSACK 《Integrative zoology》2023,18(1):27-44
Salinity (sodium chloride, NaCl) from anthropogenic sources is a persistent contaminant that negatively affects freshwater taxa. Amphibians can be susceptible to salinity, but some species are innately or adaptively tolerant. Physiological mechanisms mediating tolerance to salinity are still unclear, but changes in osmoregulatory hormones such as corticosterone (CORT) and aldosterone (ALDO) are prime candidates. We exposed larval barred tiger salamanders (Ambystoma mavortium) to environmentally relevant NaCl treatments (<32–4000 mg·L−1) for 24 days to test effects on growth, survival, and waterborne CORT responses. Of those sampled, we also quantified waterborne ALDO from a subset. Using a glucocorticoid antagonist (RU486), we also experimentally suppressed CORT signaling of some larvae to determine if CORT mediates effects of salinity. There were no strong differences in survival among salinity treatments, but salinity reduced dry mass, snout–vent length, and body condition while increasing water content of larvae. High survival and sublethal effects demonstrated that salamanders were physiologically challenged but could tolerate the experimental concentrations. CORT signaling did not attenuate sublethal effects of salinity. Baseline and stress-induced (after an acute stressor, shaking) CORT were not influenced by salinity. ALDO was correlated with baseline CORT, suggesting it could be difficult to decouple the roles of CORT and ALDO. Future studies comparing ALDO and CORT responses of adaptively tolerant and previously unexposed populations could be beneficial to understand the roles of these hormones in tolerance to salinity. Nevertheless, our study enhances our understanding of the roles of corticosteroid hormones in mediating effects of a prominent anthropogenic stressor. 相似文献
98.
Hypothalamic mTOR signaling regulates food intake 总被引:1,自引:0,他引:1
Cota D Proulx K Smith KA Kozma SC Thomas G Woods SC Seeley RJ 《Science (New York, N.Y.)》2006,312(5775):927-930
The mammalian Target of Rapamycin (mTOR) protein is a serine-threonine kinase that regulates cell-cycle progression and growth by sensing changes in energy status. We demonstrated that mTOR signaling plays a role in the brain mechanisms that respond to nutrient availability, regulating energy balance. In the rat, mTOR signaling is controlled by energy status in specific regions of the hypothalamus and colocalizes with neuropeptide Y and proopiomelanocortin neurons in the arcuate nucleus. Central administration of leucine increases hypothalamic mTOR signaling and decreases food intake and body weight. The hormone leptin increases hypothalamic mTOR activity, and the inhibition of mTOR signaling blunts leptin's anorectic effect. Thus, mTOR is a cellular fuel sensor whose hypothalamic activity is directly tied to the regulation of energy intake. 相似文献
99.
S. Nair S. E. Ullrich T. K. Blake B. Cooper C. A. Griffey P. M. Hayes D. J. Hole R. D. Horsley D. E. Obert K. P. Smith G. J. Muehlbauer B.‐K. Baik 《Cereal Chemistry》2010,87(5):461-466
Kernel hardness is an important trait influencing postharvest handling, processing, and food product quality in cereal grains. Though well‐characterized in wheat, the basis of kernel hardness is still not completely understood in barley. Kernels of 959 barley breeding lines were evaluated for hardness using the Single Kernel Characterization System (SKCS). Barley lines exhibited a broad range of hardness index (HI) values at 30.1–91.9. Distribution of kernel diameter and weight were 1.7–2.9 mm and 24.9–53.7 mg, respectively. The proportion of hull was 10.2–20.7%. From the 959 breeding lines, 10 hulled spring barley lines differing in HI values (30.1–91.2) were selected to study the associations of HI with proportion of hull, kernel weight, diameter, vitreousness, protein, β‐glucan, and amylose content. Vitreousness, evaluated visually using a light box, showed a clear distinction between hard and soft kernels. Hard kernels appeared translucent, while soft kernels appeared opaque when illuminated from below on the light box. Kernel brightness (L*), determined as an indicator of kernel vitreousness, showed a significant negative correlation (r = –0.83, P < 0.01) with HI. Protein, β‐glucan, amylose content, proportion of hull, kernel weight, and diameter did not show any significant association with HI. 相似文献
100.
Efficacy against Fasciola hepatica and the pharmacokinetics of triclabendazole administered by oral and topical routes 总被引:1,自引:1,他引:0
Objective To determine the efficacy of triclabendazole (TCBZ) against 28-day-old, early immature liver fluke in cattle and its pharmacokinetics following administration by the oral or topical (pour-on) route.
Procedures Cattle (n = 18) were infected with 500 TCBZ-susceptible liver fluke metacercariae and randomly allocated to three groups. At 28 days after infection, the groups were: (1) untreated controls; (2) treated with oral TCBZ at 12 mg/kg in combination with oxfendazole and selenium (TOS); (3) treated with pour-on TCBZ at 30 mg/kg in combination with abamectin (TA). Blood samples were taken immediately prior to treatment and serially after treatment to assess the plasma profile of TCBZ metabolites. Ten weeks after treatment all animals were slaughtered and total liver fluke counts, fluke egg counts and liver pathology were assessed.
Results Both the TOS and TA treatments resulted in significant reductions of 28-day-old liver fluke, as assessed by fluke counts and fluke egg counts at slaughter, and the reductions following TOS treatment were significantly greater than those following TA treatment. The blood profile of TCBZ metabolites in TOS-treated animals showed a significantly greater area under the plasma concentration time curve and a higher maximum observed concentration than those treated with TA. There was significantly less liver pathology in TOS-treated animals than in the TA-treated animals.
Conclusion TCBZ administered orally at 12 mg/kg resulted in greater efficacy against 28-day-old, early immature liver fluke than was achieved by topical administration at 30 mg/kg. Plasma metabolites of TCBZ were higher and liver pathology was less in TOS-treated animals than in TA-treated animals. 相似文献
Procedures Cattle (n = 18) were infected with 500 TCBZ-susceptible liver fluke metacercariae and randomly allocated to three groups. At 28 days after infection, the groups were: (1) untreated controls; (2) treated with oral TCBZ at 12 mg/kg in combination with oxfendazole and selenium (TOS); (3) treated with pour-on TCBZ at 30 mg/kg in combination with abamectin (TA). Blood samples were taken immediately prior to treatment and serially after treatment to assess the plasma profile of TCBZ metabolites. Ten weeks after treatment all animals were slaughtered and total liver fluke counts, fluke egg counts and liver pathology were assessed.
Results Both the TOS and TA treatments resulted in significant reductions of 28-day-old liver fluke, as assessed by fluke counts and fluke egg counts at slaughter, and the reductions following TOS treatment were significantly greater than those following TA treatment. The blood profile of TCBZ metabolites in TOS-treated animals showed a significantly greater area under the plasma concentration time curve and a higher maximum observed concentration than those treated with TA. There was significantly less liver pathology in TOS-treated animals than in the TA-treated animals.
Conclusion TCBZ administered orally at 12 mg/kg resulted in greater efficacy against 28-day-old, early immature liver fluke than was achieved by topical administration at 30 mg/kg. Plasma metabolites of TCBZ were higher and liver pathology was less in TOS-treated animals than in TA-treated animals. 相似文献