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991.
Satellite and research vessel observations of sea surface temperature during the southwest monsoon of 1979 show the development of large wedge-shaped areas of cold water along the Somali coast at both 5 degrees and 10 degrees N during June and July. The cold water associated with the large northern and southern Somali eddy systems could be traced several hundred kilometers offshore. By late August the cold wedge at 5 degrees N translated northeastward as far as 10 degrees N at speeds of 15 to 30 centimeters per second, indicating a coalescence of the systems. 相似文献
992.
New method for detecting cellular transforming genes 总被引:24,自引:0,他引:24
D G Blair C S Cooper M K Oskarsson L A Eader G F Vande Woude 《Science (New York, N.Y.)》1982,218(4577):1122-1125
Tumor induction in athymic nude mice can be used to detect dominant transforming genes in cellular DNA. Mouse NIH 3T3 cells freshly transfected with either cloned Moloney sarcoma proviral DNA or cellular DNA's derived from virally transformed cells induced tumors when injected into athymic nu/nu mice. Tumors were also induced by cells transfected with DNA from two tumor-derived and one chemically transformed human cell lines. The mouse tumors induced by human cell line DNA's contained human DNA sequences, and DNA derived from these tumors was capable of inducing both tumors and foci on subsequent transfection. Tumor induction in nude mice represents a useful new method for the detection and selection of cells transformed by cellular oncogenes. 相似文献
993.
For a hundred years students of the Pleistocene have looked for evidence of the climatic change which initiated the Pleistocene epoch. Glacial deposits on the continents have been of little help because of their discontinuity and because of the destructive effect of later glaciations. Hence, Pleistocene geologists have turned to the uplifted Pliocene-Pleistocene marine sediments of the Mediterranean region. In the absence of evidence of a single, clearly defined climatic change in this sedimentary section, they have agreed to define the beginning of the Pleistocene by the first appearance of Anomalina baltica, a species of benthic Foraminifera tolerant of cool water. This definition leaves much to be desired: It rests on a single benthic species whose areal distribution must have been partly determined by local conditions on the sea floor; it is useless outside of the Mediterranean region; and there is no convincing evidence that the first appearance of Anomalina baltica in the Mediterranean coincided with the onset of the first glaciation. 相似文献
994.
The values of length of synodic month, obtained from tidally controlled periodical growth patterns in mollusks and stromatolites for several geologic periods, indicate that the deceleration rate of the earth's rotation has not been constant. Two breaks in slope, in the Pennsylvanian and Cretaceous, may be related to changes in distribution of continents, oceans, and adjacent shallow seas. 相似文献
995.
996.
The current situation in mexican immigration 总被引:1,自引:0,他引:1
By 1988, the Mexican-origin population of the United States had grown to 12.1 million, largely from recent, sharp increases in immigration. The policy concerns raised by this phenomenon have been influenced by some perceptions that available research contradicts. Today most Mexican immigrants come to stay, about half are female, and they have increasingly less schooling compared to the native-born population and other immigrants. Nationally, they do not cause adverse economic effects for native-born workers and, across generations, their language and political assimilation is proceeding well. They put greater demands on education than on other public services. However, the Mexican-origin population affects the economy and public services more and differently in the areas where it is concentrated, primarily in the western United States and large urban areas. Further, the recent legalization of 2.3 million Mexican immigrants can be expected to increase the demand on public services, especially in those areas. 相似文献
997.
Role of adenine nucleotide translocator 1 in mtDNA maintenance 总被引:1,自引:0,他引:1
Kaukonen J Juselius JK Tiranti V Kyttälä A Zeviani M Comi GP Keränen S Peltonen L Suomalainen A 《Science (New York, N.Y.)》2000,289(5480):782-785
Autosomal dominant progressive external ophthalmoplegia is a rare human disease that shows a Mendelian inheritance pattern, but is characterized by large-scale mitochondrial DNA (mtDNA) deletions. We have identified two heterozygous missense mutations in the nuclear gene encoding the heart/skeletal muscle isoform of the adenine nucleotide translocator (ANT1) in five families and one sporadic patient. The familial mutation substitutes a proline for a highly conserved alanine at position 114 in the ANT1 protein. The analogous mutation in yeast caused a respiratory defect. These results indicate that ANT has a role in mtDNA maintenance and that a mitochondrial disease can be caused by a dominant mechanism. 相似文献
998.
Lahav O Naim A Buta RJ Corwin HG de Vaucouleurs G Dressler A Huchra JP van den Bergh S Raychaudhury S Sodré L Storrie-Lombardi MC 《Science (New York, N.Y.)》1995,267(5199):859-862
The quantitative morphological classification of galaxies is important for understanding the origin of type frequency and correlations with environment. However, galaxy morphological classification is still mainly done visually by dedicated individuals, in the spirit of Hubble's original scheme and its modifications. The rapid increase in data on galaxy images at low and high redshift calls for a re-examination of the classification schemes and for automatic methods. Here are shown results from a systematic comparison of the dispersion among human experts classifying a uniformly selected sample of more than 800 digitized galaxy images. These galaxy images were then classified by six of the authors independently. The human classifications are compared with each other and with an automatic classification by an artificial neural network, which replicates the classification by a human expert to the same degree of agreement as that between two human experts. 相似文献
999.
LJ Lanzerotti K Rinnert G Dehmel FO Gliem EP Krider MA Uman J Bach 《Science (New York, N.Y.)》1996,272(5263):858-860
During the Galileo probe's descent through Jupiter's atmosphere, under the ionosphere, the lightning and radio emission detector measured radio frequency signals at levels significantly above the probe's electromagnetic noise. The signal strengths at 3 and 15 kilohertz were relatively large at the beginning of the descent, decreased with depth to a pressure level of about 5 bars, and then increased slowly until the end of the mission. The 15-kilohertz signals show arrival direction anisotropies. Measurements of radio frequency wave forms show that the probe passed through an atmospheric region that did not support lightning within at least 100 kilometers and more likely a few thousand kilometers of the descent trajectory. The apparent opacity of the jovian atmosphere increases sharply at pressures greater than about 4 bars. 相似文献
1000.
Delay of disease development in transgenic plants that express the tobacco mosaic virus coat protein gene 总被引:117,自引:0,他引:117
P P Abel R S Nelson B De N Hoffmann S G Rogers R T Fraley R N Beachy 《Science (New York, N.Y.)》1986,232(4751):738-743
A chimeric gene containing a cloned cDNA of the coat protein (CP) gene of tobacco mosaic virus (TMV) was introduced into tobacco cells on a Ti plasmid of Agrobacterium tumefaciens from which tumor inducing genes had been removed. Plants regenerated from transformed cells expressed TMV mRNA and CP as a nuclear trait. Seedlings from self-fertilized transgenic plants were inoculated with TMV and observed for development of disease symptoms. The seedlings that expressed the CP gene were delayed in symptom development and 10 to 60 percent of the transgenic plants failed to develop symptoms for the duration of the experiments. Increasing the concentration of TMV in the inoculum shortened the delay in appearance of symptoms. The results of these experiments indicate that plants can be genetically transformed for resistance to virus disease development. 相似文献