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排序方式: 共有293条查询结果,搜索用时 437 毫秒
81.
82.
In methanogenic rice‐field soil, organic matter (SOM) is anaerobically fermented to acetate, CO2 and H2 which then serve as substrates for methanogenesis. The whole process is a disproportionation reaction in which part of the SOM is oxidized to CO2 and part is reduced to CH4. We were interested in the electron balance during this process. The rates VCO2 and VCH4 at which CO2 and CH4 are produced by anaerobic degradation of SOM, and the fraction RH2 of the CH4 produced by reduction of CO2 with H2 (as opposed to acetotrophic methanogenesis), depend on (i) the presence or absence of inorganic oxidants and (ii) the electron balance ΔZ. Under pseudo steady‐state conditions, where inorganic oxidants are exhausted and the rate of SOM degradation is small compared with the size of the pool, VCO2, VCH4 and RH2 are constrained by ΔZ. Conversely, ΔZ may be determined from VCO2, VCH4 and RH2, all of which may be independently measured. We measured VCO2 (0.149–0.308 μmol g?1 day?1), VCH4 (0.169–0.466 μmol g?1 day?1) and RH2 (0.19–0.35) in eight soils and obtained values of ΔZ ranging from ?0.918 to 0.035 μmol g?1 day?1. The majority (six) were negative, indicating a decrease in the oxidation state of the SOM carbon on degradation. This could be caused by humic acids acting as an electron acceptor and allowing more of the SOM to be oxidized to CO2 rather than reduced to CH4. Direct measurement of SOM carbon oxidation state Z produced values around zero (?0.1 ± 0.1), but is too insensitive to reveal changes of the magnitude of ΔZ. 相似文献
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Sebat J Lakshmi B Malhotra D Troge J Lese-Martin C Walsh T Yamrom B Yoon S Krasnitz A Kendall J Leotta A Pai D Zhang R Lee YH Hicks J Spence SJ Lee AT Puura K Lehtimäki T Ledbetter D Gregersen PK Bregman J Sutcliffe JS Jobanputra V Chung W Warburton D King MC Skuse D Geschwind DH Gilliam TC Ye K Wigler M 《Science (New York, N.Y.)》2007,316(5823):445-449
We tested the hypothesis that de novo copy number variation (CNV) is associated with autism spectrum disorders (ASDs). We performed comparative genomic hybridization (CGH) on the genomic DNA of patients and unaffected subjects to detect copy number variants not present in their respective parents. Candidate genomic regions were validated by higher-resolution CGH, paternity testing, cytogenetics, fluorescence in situ hybridization, and microsatellite genotyping. Confirmed de novo CNVs were significantly associated with autism (P = 0.0005). Such CNVs were identified in 12 out of 118 (10%) of patients with sporadic autism, in 2 out of 77 (3%) of patients with an affected first-degree relative, and in 2 out of 196 (1%) of controls. Most de novo CNVs were smaller than microscopic resolution. Affected genomic regions were highly heterogeneous and included mutations of single genes. These findings establish de novo germline mutation as a more significant risk factor for ASD than previously recognized. 相似文献
87.
Relative Contributions of Uranium, Thorium, and Potassium to Heat Production in the Earth 总被引:1,自引:0,他引:1
Data from a wide variety of igneous rock types show that the ratio of potassium to uranium is approximately 1 X 10(4). This suggests that the value of K/U approximately 1 X 10(4) is characteristic of terrestrial materials and is distinct from the value of 8 X 10(4) found in chondrites. In a model earth with K/U approximately 10(4), uranium and thorium are the dominant sources of radioactive heat at the present time. This will permit the average terrestrial concentrations of uranium and thorium to be 2 to 4.7 times higher than that observed in chondrites. The resulting models of the terrestrial heat production will be considerably different from those for chondritic heat production because of the longer half-life of U(238) and Th(238) compared with K(40). 相似文献
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Large-scale copy number polymorphism in the human genome 总被引:1,自引:0,他引:1
Sebat J Lakshmi B Troge J Alexander J Young J Lundin P Månér S Massa H Walker M Chi M Navin N Lucito R Healy J Hicks J Ye K Reiner A Gilliam TC Trask B Patterson N Zetterberg A Wigler M 《Science (New York, N.Y.)》2004,305(5683):525-528
The extent to which large duplications and deletions contribute to human genetic variation and diversity is unknown. Here, we show that large-scale copy number polymorphisms (CNPs) (about 100 kilobases and greater) contribute substantially to genomic variation between normal humans. Representational oligonucleotide microarray analysis of 20 individuals revealed a total of 221 copy number differences representing 76 unique CNPs. On average, individuals differed by 11 CNPs, and the average length of a CNP interval was 465 kilobases. We observed copy number variation of 70 different genes within CNP intervals, including genes involved in neurological function, regulation of cell growth, regulation of metabolism, and several genes known to be associated with disease. 相似文献
90.
Mumma MJ DiSanti MA Magee-Sauer K Bonev BP Villanueva GL Kawakita H Dello Russo N Gibb EL Blake GA Lyke JE Campbell RD Aycock J Conrad A Hill GM 《Science (New York, N.Y.)》2005,310(5746):270-274
We quantified eight parent volatiles (H2O, C2H6, HCN, CO, CH3OH, H2CO, C2H2, and CH4) in the Jupiter-family comet Tempel 1 using high-dispersion infrared spectroscopy in the wavelength range 2.8 to 5.0 micrometers. The abundance ratio for ethane was significantly higher after impact, whereas those for methanol and hydrogen cyanide were unchanged. The abundance ratios in the ejecta are similar to those for most Oort cloud comets, but methanol and acetylene are lower in Tempel 1 by a factor of about 2. These results suggest that the volatile ices in Tempel 1 and in most Oort cloud comets originated in a common region of the protoplanetary disk. 相似文献