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101.
A 3.5-month-old papillon puppy was brought to our clinic with chief complaints of progressive quadriparesis, ataxia and head tremor. Lesions in the cerebellum, brainstem and spinal cord were suspected on the basis of a neurological examination. No abnormality was found in a clinicopathological examination or on magnetic resonance imaging. On the basis of these results differential diagnoses including an inflammatory disease, a degenerative condition or a storage disorder were considered. Subsequently, the signs progressed and glossoplegia and dysphagia developed at six months of age. At a second magnetic resonance imaging, severe atrophy of the entire brain was found. After these examinations, the puppy was euthanased and histopathologically diagnosed with neuroaxonal dystrophy. Because magnetic resonance imaging detected abnormal features that were characteristic of neuroaxonal dystrophy in this case, we speculate that magnetic resonance imaging can assist in the pre-mortem diagnosis of this disease. 相似文献
102.
Labuschagne K Gerber LJ Espie I Carpenter S 《The Onderstepoort journal of veterinary research》2007,74(4):343-347
Culicoides biting midges (Diptera: Ceratopogonidae) are responsible for the transmission of a large number of pathogens to livestock and wild animals. In this study the presence of the genus, using light traps based at four different sites within the National Zoological Gardens of South Africa, was investigated during 2002-2004. In total, 37 species were recorded, including large numbers of Culicoides imicola Kieffer, 1913, which is responsible for the transmission of economically important arboviruses in South Africa, Europe, Middle and Far East. These results are discussed with reference to the wider Culicoides fauna in the Onderstepoort area of South Africa, their vector competence as well as biosecurity at the National Zoological Gardens. 相似文献
103.
Blood samples were obtained from privately owned cats in Connecticut and New York State, USA in 1985-1990, and analyzed for evidence of Francisella tularensis, the etiologic agent of tularemia. Of the 91 sera tested by microagglutination (MA) methods, 11 (12%) contained antibodies to F. tularensis. Analyses of the same sera by indirect fluorescent antibody (IFA) staining methods revealed 22 (24%) positives. There was good agreement in results of both tests (73% concordance). However, we measured higher titers (1:80 to 1:640) with IFA analysis than by MA methods (1:80 to 1:160). Both tests were suitable for general screening purposes. The DNA of F.tularensis was not detected in the 24 antibody-positive sera tested. Cats living in Connecticut and New York State were naturally exposed to F.tularensis or a closely related organism. With exposure to ticks, other biting arthropods, mice, and rabbits, cats are at risk for acquiring F.tularensis infections and can be an important source of information on the presence of this agent in nature. 相似文献
104.
旨在通过对北京油鸡(BY)和“广明2号”白羽肉鸡B系(广明白鸡,GM)在热应激和正常饲养条件下的脾脏转录组进行分析,鉴定两鸡种在应对热应激时的差异表达基因和信号通路,解析不同鸡种耐热性能差异的分子调控机制。试验动物采用相同饲养条件下的25日龄北京油鸡和广明白鸡,测定异嗜性粒细胞与淋巴细胞的比值(H/L)、超氧化物歧化酶(SOD)和总抗氧化能力(T-AOC)等表型数据,采集脾脏组织进行转录组测序(RNA-Seq)。基于RNA-Seq数据,结合表型进行加权基因共表达网络分析(WGCNA),筛选出与性状相关性较高的模块与基因。脾脏转录组测序结果表明,热应激组相比于对照组,北京油鸡中共鉴定到313个差异表达基因,其中169个上调表达,144个下调表达;广明白鸡中鉴定到235个差异表达基因,其中152个上调表达,83个下调表达。利用WGCNA分析,在北京油鸡中筛选出2个与H/L相关性较高的模块,在广明白鸡中筛选出4个与H/L和T-AOC强相关的模块。通过筛选模块中的Hub基因,发现两品种中均存在TRIM29基因,说明该基因可能在抗热应激方面发挥重要作用。本研究通过转录组分析,揭示了不同鸡种在热应... 相似文献
105.
<正> 淹没在水面下,几乎所有的水生值物流都出现生物膜(Characklis,1986)Gilbert等(1987)提出,先形成生物膜,后结成大的生物污垢,生物膜发展的基本阶段是: 1.细菌细胞的附着物。 2.附着细胞的连续生长和伴随着胞外物质的生成,导致微小群体生长的结合。 相似文献
106.
In this paper,four models are selected as the representatives and applied to nonlinear dynamic analysis program for space frames which is based on the beam-column elements using the finite element flexibility method and the fiber model.Park's test on combined axial and bending columns under cyclic loading are taken as the calibrations,comparisons to material and structural member level are drawn and the analytical results of various models are discussed. 相似文献
107.
This paper analyzes the SOHO and the reuse of old industry building, and deeply explores the creation and application of SOHO mode in the reuse of old industry building, furthermore, it points out the four inspirations to the reuse of old industry building, at the end, a general judgment of the development logic of SOHO is given. 相似文献
108.
Geogrid reinforced soil retaining wall(GRSRW) is composed of panel,geogrid and soil,its coupled hydromechanical structural characteristics are increasingly emphasized in practice.In this paper,based on the characteristics of the reinforcement-soil interaction,the grogrid and soil around it with a definite thickness were regarded as a kind of composite material with strain-compatible condition.A saturated porous media model was introduced to simulate the soil and reinforcement-soil composite material hereby and the mathematic model for numerical analysis on structural characteristics of GRSRW was built up.The FEM equations were deduced from the standard Galerkin procedure,resolving these equations,we can gain the relevant dynamic response of saturated GRSRW. 相似文献
109.
The agent - construction system, as a new public project management mode, has been practiced in some cities and attracted attention from the society. This paper firstly studies the features and operation modes of agent - construction system, and discusses the agent - construction system from the viewpoints of promoting competition, nourishing agent -construction enterprises, setting up a supervisory and encouraging mechanism, and its connection with the governmental project procurement system etc. 相似文献
110.
In order to settle some problems involved in applying ANSYS into nonlinear Finite Element Analysis of RC structure,this paper discusses the nonlinear FEM method for staggered joint,incorporating its experimental result.The main solved problems are as follows:(1) The fundamental process of nonlinear FEM analysis;(2) How to model the behaviors of reinforcement and concrete respectively;(3) How to model the bond-slip relationship between reinforcement and concrete. 相似文献