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Rooney HC Van't Klooster JW van der Hoorn RA Joosten MH Jones JD de Wit PJ 《Science (New York, N.Y.)》2005,308(5729):1783-1786
How plants recognize pathogens and activate defense is still mysterious. Direct interaction between pathogen avirulence (Avr) proteins and plant disease resistance proteins is the exception rather than the rule. During infection, Cladosporium fulvum secretes Avr2 protein into the apoplast of tomato leaves and, in the presence of the extracellular leucine-rich repeat receptor-like Cf-2 protein, triggers a hypersensitive response (HR) that also requires the extracellular tomato cysteine protease Rcr3. We show here that Avr2 binds and inhibits Rcr3 and propose that the Rcr3-Avr2 complex enables the Cf-2 protein to activate an HR. 相似文献
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Seifritz E Esposito F Hennel F Mustovic H Neuhoff JG Bilecen D Tedeschi G Scheffler K Di Salle F 《Science (New York, N.Y.)》2002,297(5587):1706-1708
The principles that the auditory cortex uses to decipher a stream of acoustic information have remained elusive. Neural responses in the animal auditory cortex can be broadly classified into transient and sustained activity. We examined the existence of similar principles in the human brain. Sound-evoked, blood oxygen level-dependent signal response was decomposed temporally into independent transient and sustained constituents, which predominated in different portions-core and belt-of the auditory cortex. Converging with unit recordings, our data suggest that this spatiotemporal pattern in the auditory cortex may represent a fundamental principle of analyzing sound information. 相似文献
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