A Tremor Syndrome With a Central Axonopathy in Scottish Terriers

A central axonopathy in 2 male and 1 female Scottish Terrier puppies from 3 different but related litters is reported. Clinical signs consisting of severe whole-body tremors and ataxia were first detected at the age of 10 to 12 weeks. They worsened with activity and excitement and diminished during rest or sleep. Two dogs also had paraparesis. In 1 dog the neurological deficits progressed over several months. Neuropathological examination revealed widespread axonal changes, vacuolation, and gliosis in the white matter of the central nervous system.     

Effects of Carbon Dioxide Exposure on Intensively Cultured Rainbow Trout Oncorhynchus mykiss: Physiological Responses and Fillet Attributes

Rainbow trout Oncorhynchus mykiss (261.6 × 24.7 g initial weight, mean × SEM) at 13.1 × 0.2 C were exposed for 94 d to one of three CO₂ treatments: control (22.1 × 2.8 mg/L), medium (34.5 × 3.8 mg/L), or high (48.7 × 4.4 mg/L). Trout were checked daily for survival, and fish were sampled at 0, 28, 56, and 84 d for physiological responses, growth, and fillet quality assessments. Trout were also challenged to a 15-min crowding stress at 93 d to assess their ability to initiate a stress response during hypercapnia. Chronically exposed trout showed nearly 100% survival through 84 d exposure (1 of 1,500 fish died). Growth and physiological results showed that increasing elevated CO₂, concentrations result in corresponding decreased growth rates and CO₂specific physiological parameters: The medium and high CO₂ treatments had significantly slower growth and subsequently smaller fish by 84 d. Exposed trout also showed significantly ( P < 0.05) decreased plasma chloride for medium and high CO₂ treatments compared to the control from 28 through 84 d. Decreased growth and smaller fish in the medium and high CO₂ treatments resulted in correspondingly smaller fresh and smoked fillet weights. Chronic CO₂ exposure did not result in notable changes in ultimate muscle pH. Exposure to 15-min crowding stress at 93 d resulted in significant changes in hematocrit, plasma cortisoI, glucose, and chloride for all treatment groups. CO₂-specific changes were detected in hematocrit, plasma cortisoI, and plasma chloride responses following the 15-min crowding stress.     

内燃机燃烧模型的发展现状

利用CFD技术对内燃机燃烧过程进行数值模拟已成为内燃机研究的重要工具。选用恰当的燃烧模型对准确预测内燃机燃烧过程具有重要意义。内燃机CFD燃烧模型主要针对自燃、预混燃烧和非预混燃烧3种燃烧模式,其中有些模型可以同时模拟2种模式或3种模式。内燃机新的燃烧系统的不断出现促进了燃烧模型的发展。本文以STAR—CD和FIRE软件为出发点,介绍了内燃机燃烧模型的发展现状。     

聚乙酸乙烯酯乳液胶的改性

本文介绍了用该改性乳液胶合的贴面胶合板的性能改性聚乙酸乙烯酯共聚乳液胶粘剂的聚合工艺，经过改性的乳液胶具有良好的耐水性，达到并超过日本二类特种合板标准，且生产工艺简单，原料易得，成本与普通乙酸乙烯酯均聚液接近,具有较强的实用性。     

Effects of nitrogen and water stress on the rehydration,endogenous hormonal regulation and yield of maize

Water scarcity is known to be a strong limiting factor affecting maize grown and yield in cold semi-arid regions. Numerous studies have shown that rehydration improves maize growth. Our study aimed to explore the effects of rehydration treatments on maize growth and yield under water and nitrogen stress during different growth stages. We selected the drought-tolerant maize variety Nendan 19 (ND19) and subjected it to water stress during the V6 (sixth-leaf), R2 (filling) and R6 (maturity) growth stages and a rehydration treatment after each stress stage. Our results indicated that N1 (N100 kg N ha⁻¹) and N3 (N300 kg N ha⁻¹) treatments significantly increased the leaf moisture status relative to water content (RWC), bound water content (BWC), free water content (FWC) and water potential (WP)) at different growth stages. Similar trends were observed in the accumulation of plant leaf and root hormones (zeatin+zeatin riboside, indole-3-acetic acid, abscisic acid and gibberellic acid), photosynthetic pigments and chlorophyll fluorescence. However, under the same water stress conditions, they decreased as the N rate increased and reached a minimum value in the S3 (water stress for N3) treatments. In addition, with growth stage advancement and extension of the rehydration time, both showed a gradual upward trend. The results showed that to save water resources in the cold semi-arid region, rehydration treatments (R2S1 and R2S3) significantly increased the photosynthetic pigments and chlorophyll fluorescence parameters, leaf moisture status, biomass, 100-grain weight, hormone content, ear characteristics and grain yield of maize.     

Acute toxoplasmosis in squirrel monkeys (Saimiri sciureus) in Mexico

Toxoplasma gondii causes fatal multisystemic disease in New World primates, with respiratory failure and multifocal necrotic lesions. Although cases and outbreaks of toxoplasmosis have been described, there are few genotyping studies and none has included parasite load quantification. In this article, we describe two cases of lethal acute toxoplasmosis in squirrel monkeys (Saimiri sciureus) of Mexico city. The main pathological findings included pulmonary edema, interstitial pneumonia, hepatitis and necrotizing lymphadenitis, and structures similar to T. gondii tachyzoites observed by histopathology in these organs. Diagnosis was confirmed by immunohistochemistry, transmission electron microscopy and both end point and real time PCR. The load was between <14 and 23 parasites/mg tissue. Digestion of the SAG3 gene amplicon showed similar bands to type I reference strains. These are the first cases of toxoplasmosis in primates studied in Mexico, with clinical features similar to others reported in Israel and French Guiana, although apparently caused by a different T. gondii variant.     

The pharmacokinetics and metabolism of ivermectin in domestic animal species

The pharmacokinetic properties of drugs are closely related to their pharmacological efficacy. The kinetics of ivermectin are characterised, in general terms, by a slow absorption process, a broad distribution in the organism, low metabolism, and slow excretion. The kinetics vary according to the route of administration, formulation, animal species, body condition, age, and physiological status, all of which contribute to differences in drug efficacy. Characterisation of ivermectin kinetics can be used to predict and optimise the value of the parasiticide effects and to design programmes for parasite control. This article reviews the pharmacokinetics of ivermectin in several domestic animal species.     

Field experiments to evaluate the feasibility of eradication of Aujeszky's disease virus by different vaccination schedules.

In the present report, the extent of the reduction in Aujeszky's disease virus (ADV) dissemination achieved when pigs were intensively vaccinated with gI-deleted vaccines under field circumstances, was examined. On widely dispersed breeding-fattening farms, a gI-negative status was most rapidly obtained and the rate of new waves of infections was lowest when the attenuated Bartha strain was administered to both the sows and the fatteners. It was more difficult not only to reach but also to keep a gI-negative status on farms on which the sows were vaccinated with an inactivated vaccine and the fatteners with the attenuated Bartha strain or when the fattening pigs were not vaccinated at all. In a densely populated area, 9 of the 17 farms had gI-positive fatteners at the start of the intensive vaccination programme in which the attenuated Bartha strain was given to both the sows and the fatteners. Antibodies were not detected in the sera of the fatteners of each farm at some time during the experiments, but the fatteners on 7 of the 18 farms still showed antibodies against gI after 20 months of vaccination. At the end of the experiment, the percentage of fatteners with antibodies on these farms was markedly reduced compared with the percentage at the start of the experiment. Therefore, elimination of field virus may be feasible if intensive vaccination is carried out over a sufficiently long period of time. However, the high rate of reinfections experienced either due to reintroduction of the virus or to recrudescence should be a warning against too much optimism, particularly in regions with a dense swine population.