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C-reactive protein concentration in dogs with various diseases 总被引:1,自引:0,他引:1
Nakamura M Takahashi M Ohno K Koshino A Nakashima K Setoguchi A Fujino Y Tsujimoto H 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2008,70(2):127-131
To investigate the clinical utility of C-reactive protein (CRP) determination in dogs, its plasma concentration was measured by a laser nephelometric method in 928 dogs with various diseases, and was compared with other inflammatory parameters. CRP concentration was elevated in various inflammatory diseases, this was most frequently observed in cases with neoplastic and immune-mediated diseases. All cases of pyometra, panniculitis, acute pancreatitis, polyarthritis, and hemangiosarcoma showed significantly elevated CRP concentrations. On the other hand, the CRP concentration was elevated only in few cases of neurological diseases such as epilepsy, meningoencephalitis, and hydrocephalus and endocrine diseases such as hypothyroidism, hyperadrenocorticism, and diabetes mellitus. Only a weak correlation was observed between the CRP concentration and white blood cell (WBC) counts (r=0.44) but no correlation with band neutrophil counts. There was no correlation between the CRP and albumin concentrations, but a weak negative correlation (r=-0.40) when excluding chronic intestinal diseases and nephrotic syndrome, which can cause protein loss. Thus, CRP can be useful to detect inflammations that cannot be detected by WBC and, or band neutrophil counts, suggesting that the examination of CRP concentration is essential as routine diagnostic test. 相似文献
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Ohno K Konishi S Kobayashi S Nakashima K Setoguchi A Fujino Y Nakayama H Tsujimoto H 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2006,68(9):929-933
Prognostic factors associated with survival in dogs with lymphocytic-plasmacytic enteritis (LPE) were investigated through a retrospective study. Using case records, 48 dogs diagnosed with LPE were classified as survivors (n = 32) or non-survivors (n = 16), and the clinical and clinicopathological parameters were reviewed between the 2 groups by using univariate and multivariate prognostic analysis. Compared to the hospital population, non-survivors had an overrepresentation of the Shiba breed. Results of univariate analysis indicated that anorexia, severe weight loss, packed cell volume, and total protein were significantly associated with survival for 6 months after diagnosis. In multivariate analysis, anorexia and hypoproteinemia were significantly associated with survival. Furthermore, initial response to treatment was strongly associated with poor prognosis. Based on these clinical and laboratory parameters such as anorexia, hypoproteinemia and initial response to treatment, it may be possible to predict poor prognosis in canine LPE. 相似文献
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Tsukamoto A Ohno K Tsukagoshi T Maeda S Nakashima K Fukushima K Fujino Y Tsujimoto H 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2011,73(9):1133-1138
Gastric motility is affected by several pathological conditions which may induce upper gastrointestinal clinical symptoms. The pathogenesis of canine gastric motility disorders is poorly understood because of methodological limitations. This study aimed at establishing a simple method for evaluating postprandial gastric motility in dogs. Gastric motility was ultrasonographically assessed in 7 healthy beagles using a technique previously described in humans. The motility index (MI), an indicator of gastric antral motility, was calculated by measuring the area of the gastric antrum in both a contracted and relaxed phase and by counting the number of contractions. The MI was measured every 30 min for 3 hr after feeding and compared with gastric emptying as assessed by a (13)C-octanoic acid breath test. The MI at 30 min had the lowest variability in the 7 dogs (mean SD, 9.77 ± 0.42; coefficient of variance, 4.25%), and a significant correlation was observed with gastric emptying coefficient (R(2)=0.8126, P=0.005) and half-emptying time (R(2)=0.654, P=0.027). When atropine was administered, a significant decrease in the MI at 30 min was observed compared with the control (9.77 ± 0.42 vs. 5.19 ± 0.22, P=0.0003). In conclusion, evaluation of the MI at 30 min is suitable for assessing gastric motility and enables us to assess gastric motility simply in a short time. By using this method, further studies for the pathogenesis of canine gastric motility disorders are warranted. 相似文献
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We evaluated the suitability of the Rothamsted Carbon (RothC) model for long-term experiments on Japanese non-volcanic upland soils using 6 long-term experimental data sets: 2 Brown Lowland Soils, 2 Yellow Soils, 1 Gray Lowland Soil, and 1 Brown Forest Soil. The predicted changes in the content of soil carbon with time were very close to the observed values in almost all the treatments at all the 6 sites. These 6 sites were distributed from North to South across Japan and included a variety of climatic conditions, soil textures, and land management practices. We therefore concluded that the RothC model adequately simulated changes in the soil carbon content with time in Japanese non-volcanic upland soils. 相似文献