Additive genetic and maternal effects on postweaning growth and carcass traits in rabbits

SUMMARY: Additive genetic and maternal effects were estimated for postweaning growth traits and carcass traits using a derivate-free REML procedure under animal model. The traits studied were weight at 84 days of age, age at slaughter, postweaning ADG, dressing percentage, weight of kidney and pelvic fat, and muscle pH value and electrical conductivity in the semimembranosus muscle. Heritability estimates from a total of 728 rabbits in a reciprocal crossbreeding experiment ranged from 0.15 to 0.26 for postweaning growth traits, 0.21 for dressing percentage, 0.38 for weight of kidney and pelvic fat, 0.02 for pH value, and 0.51 for electrical conductivity. Considerable maternal effects were present in postweaning growth traits and in weight of kidney and pelvic fat. Genetic correlation estimates indicated that genetic selection for postweaning daily gain would lead to lower dressing percentages (- 0.51) and leaner carcasses (- 0.34). The genetic relationships between ADG after weaning and pH value (- 0.90), and between ADG and electrical conductivity (0.58) illustrated a shifting towards a glycolytic energy metabolism of the muscle due to increased growth. Litter size at birth was found to be a significant source of variation for all postweaning growth traits (p < 0.001) and for electrical conductivity (p < 0.05). Genetic selection for litter size at birth would result in decreased growth rates, lower dressing percentage and enhanced adiposis. ZUSAMMENFASSUNG: Die Sch?tzung additiv-genetischer und maternaler Effekte auf Mastleistungs- und Schlachtk?rpermerkmale beim Kaninchen Additiv-genetische und maternale Effekte wurden für Mastleistungsmerkmale nach dem Absetzen und für Schlachtk?rpermerkmale anhand eines Tiermodells (DFREML-Methode) gesch?tzt. Bei den untersuchten Merkmalen handelt es sich um das 84-Tage-Gewicht, das Schlachtalter, Zunahmen nach dem Absetzen, Ausschlachtungsprozente, Nieren- und Beckenfettgewicht und um den pH-Wert und die elektrische Leitf?higkeit im M. semimembranosus. Die Heritabilit?tssch?tzungen an insgesamt 728 Tieren, die aus einem reziproken Kreuzungsversuch stammten, lagen bei den Wachstumsmerkmalen zwischen h(2) = 0,15 und h(2) = 0,26. Sie betrugen h(2) = 0,21 für die Ausschlachtungsprozente, h(2) = 0,38 für das Nieren- und Beckenfettgewicht, h(2) = 0,02 für den pH-Wert und h(2) = 0,51 für die Leitf?higkeitsmessung. Die Sch?tzung genetischer Korrelationen deutet an, da? eine genetische Selektion auf t?gliche Zunahmen nach dem Absetzen zu einer verringerten Ausschlachtung (- 0,51) und zu magereren Schlachtk?rpern führen würde. Die genetischen Beziehungen zwischen den Zunahmen und dem pH-Wert (- 0,90) und zwischen den Zunahmen und der elektrischen Leitf?higkeit (0,58) lassen eine Verschiebung in Richtung eines glykolytischen Muskelenergiestoffwechsels bei verst?rktem Wachstum erwarten. Die Wurfgr??e bei der Geburt stellt eine signifikante Variationsursache für die Mastleistungsmerkmale nach dem Absetzen (p < 0,001) una für die elektrische Leitf?higkeit (p < 0,05) dar. Bei einer Erh?hung der Wurfgr??e durch Selektion sind verminderte Wachstumsraten, geringere Ausschlachtungsprozente und verst?rkte Verfettung zu befürchten.     

关于广东蚕业“十一五”发展规划的浅见

目前全国茧丝绸行业都在讨论研究行业“十一五”发展规划，本文就广东蚕业“十一五”发展规划提出一些浅见，供同行参考。     

Association of polymorphism of Fc receptor γ chain gene at position-29 in promoter with the susceptibility to systemic lupus erythematosus in southern Chinese

AIM:To detect the association between the polymorphism of Fc receptor γ chain gene at position-29 in promoter and systemic lupus erythematosus(SLE).METHODS:The genotypes at position -29 in promoter of Fc receptor γ chain gene were determined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method in 180 patients with SLE and 140 ethnically matched controls in southern China.RESULTS:The frequencies of TT genotype(33.3%) and T allele (54.4%) at position -29 in patients with SLE were significantly higher than those in controls (17.2% and 42.9%, respectively), whereas, the frequencies of GG genotype (24.4%) and G allele (45.6%) in patients with SLE were remarkably lower than those in controls (31.4% and 57.1%, respectively) (P＜0.05). The TT genotype and T allele at position -29 were not associated with lupus nephritis in SLE patients (P＞0.05).CONCLUSION:Our results indicate that the T allele at position -29 in promoter of Fc receptor gene probably contributes to the susceptibility to SLE, but does not play a role in the occurrence of lupus nephritis.     

优质高产菜豆新品种‘无筋2号''

‘无筋2号’为优质高产菜豆新品种，生长势旺盛，耐肥抗倒，播种至采鲜荚生育期45d左右，结荚性好，豆荚饱满，商品性好，适宜速冻加工出口，鲜荚产量17—18t/hm^2，高产地块可达20t/hm^2以上。     

Cloning of p15INK4b related gene CCRG and expression analysis in the renal carcinoma

AIM and METHODS:To analysis the factor that involved in renal carcinogenesis, we used the bait gene AK001518 to screen GenBank. To understand the relationship between cell cycle related gene(CCRG) and p15, we did RT-PCR and Northern Blot experiments. Then we examined CCRG expression level in renal carcinogenesis. RESULTS:Gained a function unknown gene CCRG that was 67% a mino acid identical with the gene AK001518 that was regulated by p15. It was shown that the CCRG mRNA was dramatically decreased when p15 gene was over-expressed. CCRG expression level was much higher in tumor tissues and cells than normal tissues and cells. CONCLUSION:The novel gene CCRG expressed highly in the renal carcinoma, which might play a significant role in the renal carcinogenesis.     

Expression and role of CD134 and NF-κB in renal tissue of lupus nephritis

AIM:To investigate the role of CD134 (OX40) and NF-κB in the pathogenesis of lupus nephritis (LN).METHODS:Renal in situ CD134 and NF-κB expression were examined in 40 biopsy specimens from LN patients by immunohistochemistry and microwave-based immunohistochemistry, respectively. The relationship between expression of CD134 and NF-κB was analyzed.RESULTS:The expression of glomerular and tubular CD134 and NF-κB in LN were higher than that in normal control, especially in class Ⅳ LN, where there was intense staining of endothelial cell, distal tubules, and interstitial mononuclear cell. The CD134 expression of glomerular and tubular was closely related to NF-κB expression, respectively (r=0.5542, P＜0.05;r=0.6279, P＜0.05). CONCLUSIONS:The abnormal expression of costimulatory molecule CD134 was well evidenced in LN. Strong expression of renal in situ NF-κB was likely mediated by CD134 signal pathway, which may play an important role in the pathogenesis of LN.     

库布齐沙漠穿沙公路沙害综合防治技术

库布齐穿沙公路修建在库布齐沙漠高大的流动沙丘区 ,风沙流侵袭与沙丘整体前移埋压公路是主要沙害形式。现有防沙措施是沙障保护下的人工植被及天然植被相结合的综合防护体系 ,固沙及阻沙效益明显。目前要解决的是尽快形成公路两侧稳定的植被群落 ,以保证公路的长期畅通     

优质茄子新品种引茄1号的选育

引茄 1号为杂种一代 ,植株生长势旺盛 ,果实细长、紫红色 ,果面光滑 ,果肉细嫩 ,平均单果质量 6 0～70kg ,抗青枯病和绵疫病 ,产量 30 0 0～ 4 0 0 0kg·(6 6 7m2 ) -1,适于我国喜食长茄地区的保护地和露地栽培。     

Expression of undulin in experimental rat liver fibrosis

AIM: To observe the expression of undulin (Un) in liver tissue and to clarify the diagnostic significance of serum Un in experimental rat liver fibrosis. METHODS: Rat liver fibrosis was induced by carbon tetrachloride. The expression of Un in liver tissue was detected by immunohistochemical method. Serum Un levels was measured by enzyme immunoassay. RESULTS: Expression of Un increased in fibrotic liver than normal liver, and it was mainly distributed in portal tract stroma, central veins and fibrotic septa in fibrotic liver. Also, the level of serum Un was significantly higher in fibrotic liver than normal liver. CONCLUSION: These data suggest that Un should be a component of the hepatic extracellar matrix, and its expression could be increased greatly in fibrotic rat liver. Serum Un levels may be used as an indicator in liver fibrosis diagnosis.