Effect of hydrogen sulfide on myocardial fibrosis and PPARγ and NF-κB expression in rat model of diabetes

AIM: To explore the effects of hydrogen sulfide (H₂S) on the myocardial fibrosis in a rat model of diabetes and its mechanism.METHODS: Single intraperitoneal injection of streptozotocin (STZ) was utilized to establish a rat model of diabetes. Sodium hydrosulfide was used as an exogenous donor of hydrogen sulfide. Male SD rats were randomly divided into control group, STZ group, STZ+H₂S group and H₂S group. Eight weeks later, HE and VG staining methods were used to observe the collagen distribution and collagen volume fraction was measured by image analysis. The expression levels of type I collagen, PPARγ and NF-κB in the cardiac tissues were determined by Western blotting.RESULTS: Compared with control group, collagen distribution and the expression levels of type I collagen and NF-κB in the cardiac tissues were markedly increased (P<0.05), while PPARγ was significantly decreased in STZ group (P<0.05), but these indexes were reversed significantly in STZ+H₂S group (P<0.05). The expression levels of type I collagen, PPARγ and NF-κB had no significant difference between H₂S group and control group.CONCLUSION: Hydrogen sulfide attenuates cardiac fibrosis in diabetic rats, and its mechanism may be related to PPARγ-NF-κB signaling pathway.     

Secondary Metabolites from Marine Sponges of the Genus Oceanapia: Chemistry and Biological Activities

In this review, we summarized the distribution of the chemically investigated Oceanapia sponges, including the isolation and biological activities of their secondary metabolites, covering the literature from the first report in 1989 to July 2019. There have been 110 compounds reported during this period, including 59 alkaloids, 33 lipids, 14 sterols and 4 miscellaneous compounds. Besides their unique structures, they exhibited promising bioactivities ranging from insecticidal to antibacterial. Their complex structural characteristics and diverse biological properties have attracted a great deal of attention from chemists and pharmaceuticals seeking to perform their applications in the treatment of disease.     

小型植保无人机超低量喷雾对荒漠绿洲麦区小麦白粉病的防治效果

研究小型植保无人机超低量喷雾对小麦白粉病的防治效果,为科学使用小型植保无人机防控小麦病害提供指导。采用随机区组的方法,定点调查各处理小麦白粉病发生情况,评价供试药剂对小麦白粉病的防治效果。结果表明,240 g/L氯氟醚·吡唑酯SC 180 g/hm²、19%啶氧·丙环唑SC 199.50 g/hm²和 23%醚菌·氟环唑 SC 103.50 g/hm²添加增效剂迈飞对小麦白粉病具有较好的防效,防效分别为77.88%、74.23%和 73.26%。42%苯菌酮 SC 189.00 g/hm²、430 g/L戊唑醇悬浮剂SC 129.00 g/hm²、75%肟菌·戊唑醇 WG 202.50 g/hm²和 40%腈菌唑 WP 120.00 g/hm²添加增效剂迈飞对小麦白粉病防效在60.90%～65.72%之间。7 种药剂均可用于小型植保无人机超低量喷雾防治小麦白粉病,为了减缓抗药性的产生,建议在生产上轮换使用。     

水稻梯田土壤速效氮、磷、钾的迁移与分布特征研究

研究水稻梯田氮、磷、钾速效成分迁移与分布规律,为实现精准配方施肥提供依据。选择白石村10个有水稻梯田分布的村民小组,每个村民小组为一个采样区,按照水流路径,每个采样区梯田分成6层,每层采用“S”形布点法采集5个土样,分别测定土壤的碱解氮、速效磷和速效钾含量,并建立与梯田层次间的函数关系式,研究其横向迁移分布情况与规律。结果表明：白石村土壤主要养分平均含量：碱解氮103.3±13.67 mg/kg、速效磷42.84±5.42 mg/kg、速效钾95.25±13.91 mg/kg,营养等级为中上;碱解氮、速效钾从上层梯田向下层梯田迁移,并有显著的指数回归趋势,平均相关系数分别为0.9719和0.9885,低洼地氮素含量偏高;速效磷纵向迁移不明显,但其含量与碱解氮含量呈负相关,拟合度为72.72%。白石村水稻梯田碱解氮、速效钾含量随着水流由上层向下层迁移,并具有明显的指数回归趋势;速效磷随水流迁移不明显,分布相对稳定,有富集倾向。     

糯性普通小麦的选育及其淀粉品质

普通小麦胚乳淀粉一般由20%~30%的直链淀粉和70%~80%的支链淀粉组成。在自然界,大多数禾谷类作物,如玉米、水稻、高粱等均存在直链淀粉含量几乎为0的糯性类型。普通小麦是异源六倍体,迄今为止尚未发现自然界存在糯性小麦。由于小麦淀粉的构成及品质与面条品质关系密切,在发达国     

不同秧龄对双季稻早衰的影响研究

从双季稻的产量构成因素及产量的变化入手,详细研究了不同秧龄对双季稻早衰的影响程度,确定了在常规栽培条件下的最适宜秧龄期:早稻为15~25d,晚稻秧龄越短越好。     

三峡库区坡地梨-旱稻农业模式生态经济分析

运用生态经济学原理对三峡库区坡地新建梨-旱稻复合系统的生态效益和经济效益进行了研究。结果表明:与清耕梨园相比,梨园间作旱稻并秸秆还田后,有良好的水土保持作用和改土培肥效果,同时能有效控制田间杂草,减少梨园病虫害的发生,消减非点源N污染负荷60.19 kg/hm2,非点源P污染负荷8.0kg/hm2。与单一系统相比,复合系统提高土地利用率44%,能量经济系数上升2%。研究结果表明:梨-旱稻复合系统是一种具有良好生态效益的高效种植模式,值得在库区大力推广。     

山西苔草品种资源及分布

苔草属植物是我国植物区系组成的主要大属之一。从生物学特性的角度,综述山西苔草属植物分布分类特点,提出了适宜作为草坪开发利用的苔草属植物品种。     

多花黑麦草新品系产量及农艺性状研究初探

试验对多花黑麦草新品系的植物学性状、农艺性状、生长动态及拔节期营养物质含量进行了研究。结果表明,多花黑麦草新品系生育期为234 d,生长发育迅速,特别是冬春季生长优势明显;年产草量(DM)可达15 469kg/hm2;植株高大,叶量丰富、叶片宽大,拔节期粗蛋白含量达16.17％,表现出明显的优良牧草性状;在南方亚热带地区生长良好,是优良的多花黑麦草新品系。     

激素免疫法对家畜生殖内分泌的调节及其应用

激素免疫中和技术基于激素的内分泌机制,利用激素免疫动物,改变动物体内激素正常代谢水平,以达到提高动物生产性能的目的。目前该项技术已在动物繁育上显示出很大的潜力,它在提高动物繁殖和应用于免疫去势等方面显示出优势。作者主要综述了激素免疫的作用机理在畜牧生产的应用以及影响激素免疫效果的因素等研究内容。