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991.
Qiaofeng Wu Chenhuan Yu Yunliang Yan Jing Chen Chunchun Zhang Xinxin Wen 《Fitoterapia》2010,81(5):429-433
An ethanolic extract and ethyl acetate fraction (EFMS) prepared from Mosla scabra showed potential inhibition against influenza viruses. The compounds isolated from EFMS were elucidated to be ursolic acid (1), 5-hydroxy-6,7-dimethoxyflavone (2), 5-hydroxy-7,8-dimethoxyflavone (3), apigenin (4) and acacetin (5) based on their spectral analysis. Compounds 2, 3, 4 and 5 showed significant anti-influenza viruses activities. Compared with ribavirin, EFMS appeared to have similar efficacy against influenza viruses, was considered to be less toxic and may warrant further evaluation as a possible agent for the treatment of influenza. 相似文献
992.
Xiongfei Wu Chenggang Li Guozhen Xing Xinming Qi Jin Ren 《Journal of toxicologic pathology》2013,26(4):385-392
Cyp2e1 plays an important role in chemically induced hepatocarcinogenesis. Resveratrol (REV) is known to prevent diethylnitrosamine (DEN)-induced hepatocarcinogenesis, but its effects on this process induced by DEN and 2-acetylaminofluorene (2-AAF) and the role of Cyp2e1 remain unclear. In this study, glutathione S-transferase placental form (GST-P)-positive foci were used as a marker of hepatocarcinogenesis. REV or diallyl disulfide (DADS, an inhibitor of Cyp2e1) significantly reduced both the area and number of GST-P-positive foci induced by DEN and 2-AAF. Treatment with REV or DADS also markedly decreased the expression of Cyp2e1 in the rat liver. By immunohistochemical staining of serial liver sections, we found that the expression of Cyp2e1 in GST-P-positive foci showed three distinct patterns: decreased in GST-P foci, increased in GST-P foci when compared with surrounding liver tissue and mixed type. The number of GST-P foci with increased Cyp2e1 expression was greater than the number of GST-P foci with decreased Cyp2e1. Protein levels of GST-P and Cyp2e1 were also higher in foci compared with surrounding liver tissue. REV or DADS significantly reduced the expression of GST-P and Cyp2e1 in both foci and surrounding liver tissue. Taken together, these results suggested that REV has a significant inhibitory effect on chemically induced hepatocarcinogenesis, which may be attributed to downregulation of Cyp2e1. 相似文献
993.
植被恢复治理水土流失初探 总被引:3,自引:0,他引:3
江西是个多山地区,由于地质构造、暴雨等自然因素和乱砍滥伐、无序开垦等人为因素,导致地质灾害频繁发生、水土流失十分严重。在讨论江西省水土流失基本情况的基础上,提出了治理水土流失的植被恢复的方法与技术,并分析了兴国县和笔者自行研究的治理水土流失的多种生态农业模式。 相似文献
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998.
1-甲基环丙烯处理对不同成熟度薄皮甜瓜贮藏特性的影响 总被引:2,自引:0,他引:2
以京蜜薄皮甜瓜为试材,采用体积浓度2μL·L-1的1-甲基环丙烯(1-MCP)分别处理八成熟和九成熟薄皮甜瓜,随后置于15℃冷库中贮藏,贮藏期间每3d测定相关生理和品质指标变化。结果表明:成熟度对薄皮甜瓜贮藏特性有显著影响,八成熟比九成熟薄皮甜瓜耐贮;1-MCP处理可以显著抑制不同成熟度薄皮甜瓜呼吸强度、乙烯释放速率,从而减少其贮藏期间质量损失,延缓果实表皮颜色转黄和后熟过程,降低贮藏期间腐烂率,保持其食用品质和口感,延长薄皮甜瓜货架期;八成熟的1-MCP处理组贮藏效果最好。 相似文献
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Based on agriculture production knowledge and computer technology, this paper applied database, artificial intelligent, management information system, decision support system, network technology and information integration technology to the field of soybean production, and offered decision support to users in imitating the curse during which experts solved the problems, therefore, guided production practice, introduced structure and function of decision support system of soybean, and then we analyzed the design of the knowledge base and the realization of inference engine in details as well. 相似文献