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591.
Siamudaala VM Bwalya JM Munang'andu HM Munag'andu HM Sinyangwe PG Banda F Mweene AS Takada A Kida H 《The Japanese journal of veterinary research》2006,54(1):15-23
Anthrax is endemic in Western and North-western Provinces of Zambia. The disease occurs throughout the year and impacts negatively on the economy of the livestock industry and public health in Zambia. During 1989-1995, there were 1626 suspected cases of anthrax in cattle in Western province and of these 51 were confirmed. There were 220 cases of human anthrax cases in 1990 alone and 248 cases during 1991-1998 with 19.1% and 7.7% case fatality rates, respectively. Interplay of the ecology of affected areas and anthropogenic factors seem to trigger anthrax epidemics. Anthrax has drawn considerable attention in recent years due to its potential use as a biological weapon. In this paper, the history, current status and approaches towards the control of the disease in Zambia are discussed. Quarantine measures restrict trade of livestock and exchange of animals for draught power resulting in poor food security at household levels. Challenges of anthrax control are complex and comprise of socio-political, economical, environmental and cultural factors. Inadequate funding, lack of innovative disease control strategies and lack of cooperation from stakeholders are the major constraints to the control of the disease. It is hoped that the information provided here will stimulate continued awareness for the veterinary and medical authorities to maintain their surveillance and capabilities against the disease. This may lead to a culminating positive impact on livestock and human health in the southern African region. 相似文献
592.
Context
Knowledge of how environmental gradients generate changes in community composition across forest landscapes (β-diversity) represents a critical issue in the era of global change, which exerts especially powerful impacts by shifting disturbance regimes.Objectives
We analyzed the response of tree communities to increased disturbance rates that were linked to European settlement at the temperate-boreal interface of eastern Canada. We tested whether disturbance has led to spatial homogenization or heterogenization, and to decoupling or strengthening of community-environment relationships.Methods
We used a reconstruction of pre-industrial tree communities based on historical land survey records (1854–1935), together with modern data, to assess changes in tree β-diversity patterns. Then, β-diversity was partitioned into fractions explained by spatial (dbMEM) and environmental variables (latitude, elevation, slope, drainage and surface deposits) in order to assess changes in spatial structures and community-environment relationships.Results
In pre-industrial times, environmental variables explained only a small proportion of β-diversity since dominant taxa were present across the range of environmental gradients, whereas habitat specialists were very rare. Between pre-industrial and modern times, our analysis highlights an increase in β-diversity and the proportion of β-diversity that was explained by environmental variables. Increased disturbance rates have favored early-successional habitat specialist taxa and reduced the habitat breadth of pre-industrial generalists, thereby increasing the strength of community-environment relationships.Conclusions
Our results support that disturbance can alter the strength of community-environment relationships and also suggest that functional traits of species within the regional pool could predict whether or not disturbance alters such relationships.593.
Ron Porat Victor Vinokur Batia Weiss Lea Cohen Avinoam Daus Eliezer E. Goldschmidt Samir Droby 《European journal of plant pathology / European Foundation for Plant Pathology》2003,109(9):901-907
-Aminobutyric acid (BABA), an inducer of pathogen resistance in plants, induced disease resistance in reproductive parts of the plant, such as grapefruit peel tissue. Application of BABA to specific wound sites on the fruit peel surface induced resistance to Penicillium digitatum, the main postharvest pathogen of citrus fruit, in a concentration-dependent manner, being most effective at 20mM, and rather less effective at either higher or lower concentrations. The effect of BABA in inducing resistance to P. digitatum in the fruit peel surface was local and limited to the vicinity (within 1–2cm) of the BABA-treated site. In addition to inducing pathogen resistance, increasing concentrations of BABA (from 1 to 100mM) also exhibited direct antifungal activity and inhibited P. digitatum spore germination and germ tube elongation in vitro. The induction of resistance to P. digitatum by BABA was accompanied by the activation of various pathogen defense responses in grapefruit peel tissue, including activation of chitinase gene expression and protein accumulation after 48h, and an increase in phenylalanine ammonia lyase (PAL) activity after 72h. 相似文献
594.
Alan M. Norris DVM Elizabeth J. Laing DVM DVSc Victor E. O. Valli DVM PhD Stephen J. Withrow DVM Dennis W. Macy DVM Gregory K. Ogilvie DVM Jim Tomlinson DVM Dudley McCaw DVM Guy Pidgeon DVM Robert M. Jacobs DVM PhD 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1992,6(3):145-153
One hundred and fifteen dogs with neoplasms of the lower urinary tract (bladder and/or urethra) were retrospectively evaluated at five referral institutions participating in ongoing studies by the Veterinary Cooperative Oncology Group. Most tumors were malignant (97%) and of epithelial origin (97%). Lower urinary tract tumors were more common in older dogs weighing greater than 10 kg. The following significant (P less than 0.05) statistical associations were found using the University of Guelph hospital population as control; there was no sex predisposition although the female:male ratio was 1.95:1. Neutered dogs were predisposed as were Airedale Terriers, Beagles, and Scottish Terriers, whereas German Shepherds were significantly under-represented among dogs with lower urinary tract tumors. These statistical associations should be interpreted cautiously because of possible demographic differences in hospital populations among the University of Guelph and other cooperating institutions. There were no significant correlations between age, gender, weight, breed, response to therapy, and survival time. Clinical signs were indicative of lower urinary tract disease and included hematuria, stranguria, and pollakiuria. The laboratory data were nonspecific except for urinalysis test results. Hematuria and inflammatory urinary sediments were most commonly reported; neoplastic cells were identified in the urine sediment of 30% of dogs with lower urinary tract tumors. Contrast cystography was a useful noninvasive diagnostic method since 96% of the dogs had a mass or filling defect in the lower urinary tract demonstrated by this technique.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
595.
Navarro-Llopis V Sanchis-Cabanes J Ayala I Casaña-Giner V Primo-Yüfera E 《Pest management science》2004,60(9):914-920
Two field trials in citrus orchards in Turis (Valencia, Spain) and Denia (Alicante, Spain) were performed in order to test the sterilant effect of the insect growth regulator lufenuron against wild medfly Ceratitis capitata (Wiedemann) populations. Two application methods for lufenuron were tested: spraying, in spots, an emulsion of lufenuron in a protein bait, and hanging delta traps that contained a proteinaceous gel with lufenuron (solid bait). The sterilant effect was measured as medfly population reduction, reduction of fruit damage in treated fields, and the number of eggs hatching in punctured fruits. In order to assess the efficacy of lufenuron treatments, we recorded results obtained from two different zones in both trial fields: an outer zone, close to untreated fields, and an inner zone, in the centre of lufenuron treated fields. We observed a minimum sterilant effect in the outer zone and a maximum sterilant effect in the inner one. The maximum sterilant effect was in the inner zone, where a reduction of medfly population of 80.4% in the sprayed field and a reduction of 77.6% in the solid bait field was observed. In addition, the greater the distance from the untreated zones of the treated orchard (inwards), the lower the fruit damage and medfly population level. In this inner zone, fruit punctured by medfly developed significantly fewer larvae (38.8%) than punctured fruits from the outer zone (68.6%). In addition, we recorded the decline in the activity of the lufenuron treatments with time. Lufenuron activity persisted in field for at least 2 weeks with spray applications, and for 3 months with bait gels. 相似文献
596.
597.
Pharmacokinetic characteristics and tissue residues for marbofloxacin and its metabolite N-desmethyl-marbofloxacin in broiler chickens 总被引:1,自引:0,他引:1
Anadón A Martínez-Larrañaga MR Díaz MJ Martínez MA Frejo MT Martínez M Tafur M Castellano VJ 《American journal of veterinary research》2002,63(7):927-933
OBJECTIVES: To determine pharmacokinetic characteristics of marbofloxacin after a single IV and oral administration and tissue residues after serial daily oral administration in chickens. ANIMALS: 40 healthy broiler chickens. PROCEDURE: Two groups of chickens (groups A and B; 8 chickens/group) were administered a single IV and oral administration of marbofloxacin (2 mg/kg). Chickens of group C (n = 24) were given serial daily doses of marbofloxacin (2 mg/kg, PO, q 24 h for 3 days). Plasma (groups A and B) and tissue concentrations (group C) of marbofloxacin and its major metabolite N-desmethyl-marbofloxacin were determined by use of high-performance liquid chromatography. Residues of marbofloxacin and N-desmethylmarbofloxacin were measured in target tissues. RESULTS: Elimination half-life and mean residence time of marbofloxacin in plasma were 5.26 and 4.36 hours after IV administration and 8.69 and 8.55 hours after oral administration, respectively. Maximal plasma concentration was 1.05 microg/ml, and interval from oral administration until maximum concentration was 1.48 hours. Oral bioavailability of marbofloxacin was 56.82%. High concentrations of marbofloxacin and N-desmethyl-marbofloxacin were found in the kidneys, liver, muscles, and skin plus fat 24 hours after the final dose of marbofloxacin; however, marbofloxacin and N-desmethyl-marbofloxacin were detected in only hepatic (27.6 and 98.7 microg/kg, respectively) and renal (39.7 and 69.1 microg/kg, respectively) tissues 72 hours after termination of marbofloxacin treatment. CONCLUSIONS AND CLINICAL RELEVANCE: Analysis of pharmacokinetic data obtained in this study reveals that a minimal therapeutic dose of 2 mg/kg, PO, every 24 hours should be appropriate for control of most infections in chickens. 相似文献
598.
Valli VE 《Journal of the American Veterinary Medical Association》2002,221(6):778; author reply 778
599.
Lung inflammation is often associated with sustained neutrophil migration into the lung tissue, causing undesired side effects, i.e. substantial damage of lung tissue and fibrin deposition, which hamper complete recovery. The need for additional anti-inflammatory treatment strategies focused attention on the function of cellular adhesion molecules (CAMs) on the leukocyte membrane, which guide migration of leukocytes across the endothelium to the site of inflammation. Recent data indicate that neutrophil migration in the lung is mediated by unique pathways, involving different CAM as compared to other organs. These pulmonary characteristics of neutrophil migration enable specific targeting of CAM for anti-inflammatory treatment of pneumonia. In addition, the recent interest in intracellular signaling revealed that most CAM not only function in adhesion, but also play an important role in initiation of intracellular signal transduction and vice versa may be modulated by intracellular signaling molecules (ISMs). In this review, the mechanisms of neutrophil migration in the lung and the role of ISM with respect to CAM function are described in the context of potential anti-inflammatory intervention strategies. 相似文献
600.