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41.
ANDRÉ DESROCHERS DMV MS GUY ST-JEAN DMV MS Diplomate ACVS DAVID E. ANDERSON DVM MS Diplomate ACVS DONNA P. ROGERS BS M.M. CHENGAPPA BVSc PhD Diplomate ACVM 《Veterinary surgery : VS》1996,25(4):336-341
One hundred seventeen cattle that had undergone surgery were assigned randomly to two preoperative skin preparation protocols. Group 1 (60 animals) skin preparation was with povidone-iodine soap and isopropyl alcohol, whereas group 2 (57 animals) had skin preparation with chlorhexidine gluconate and isopropyl alcohol. Quantitative microbial culture plates were used to estimate the number of colony forming units (CFUs) before skin preparation (prescrub), after skin preparation (postscrub), after surgery (postoperative), and in room air (environment). A significant decrease in CFU occurred postscrub for both skin preparations ( P <.05). Chlorhexidine and alcohol preparation resulted in significantly fewer CFUs (LSMean ± SE = 2.79 CFU ± 1.74) and a greater percentage reduction in CFUs (98.64%± 2.01) postscrub than povidone and alcohol (LSMean ± SE = 10.27 CFUs ± 1.51, 93.29%± 1.85); ( P <.005). Group 2 had a significantly higher frequency of negative cultures postscrub (49.1%) compared with group 1 (18.3%) ( P <.001). The number of postoperative CFUs were not significantly different between the two treatment groups. Wound infection frequency for clean surgical procedures was not significantly different between the two skin preparation protocols (group 1 = 9.8%, group 2 = 10.7%), however, infection frequency was significantly higher for surgical procedures with a ventral abdominal approach (5 of 14, 35.7%), compared with a flank approach (1 of 41, 2.4%) or other approaches (orthopedic procedures) (1 of 16, 6.3%) ( P <.05). Both skin preparation protocols were effective and safe in decreasing the skin microflora population of cattle before surgery and although preparation with chlorhexidine gluconate and alcohol resulted in less CFUs immediafly postscrub, the frequency of surgical wound infection was similar for both protocols. 相似文献
42.
Brett M. Kantrowitz DVM Thomas G. Nyland DVM Paul Fisher BS 《Veterinary radiology & ultrasound》1989,30(5):222-226
A duplex ultrasound system incorporating a pulsed wave Doppler ultrasound probe with conventional B-mode real-time imaging was used to evaluate portal vein blood flow in eight normal dogs. Adequate visualization of the cranial abdominal vessels was obtained from the right lateral 11th or 12th intercostal space. Doppler spectral analysis showed non-pulsatile flow with a wide range of linear flow velocities across the vessel lumen typical of laminar blood flow. Results for portal vein blood flows were 49.8 ± 13.5 ml/min/kg body weight (mean ± SD) with a range of 37.8 - 76.8 ml/min/kg body weight. These values overestimate portal blood flow by approximately 2 times when compared with published studies using invasive techniques. This overestimation is primarily due to the use of the maximal flow velocity in the blood flow calculations. 相似文献
43.
Richard J. Joseph DVM Kay Allyson BS Thomas K. Graves Mark J. Rondeau PhD Mark E. Peterson DVM 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1987,1(4):170-174
We evaluated three reflectance meters (Accu-Chek II, Glucometer II, and Glucoscan 2000) and two reagent strips (Chemstrip bG and Glucostix) for accuracy and precision in determining blood glucose concentrations in the dog. To evaluate accuracy, we compared results of blood glucose determinations performed on 95 samples using the various strips and meters vs. the glucose concentrations obtained using the glucose-oxidase method on a Beckman Glucose Analyzer. Accuracy was evaluated statistically using least squares regression analysis. To evaluate precision, samples in various ranges of blood glucose concentration were tested repeatedly (20 times within a 1-hour period) on the same reflectance meter. Coefficient of variation (CV) was determined to evaluate reproducibility of results. Overall, there were significant correlations (P less than 0.001) between the laboratory glucose values and the blood glucose concentrations obtained with Chemstrip bG (r = 0.976), Glucostix (r = 0.904), Accu-Chek II (r = 0.986), Glucometer II (r = 0.911) and Glucoscan 2000 (r = 0.944). In the precision study, all three meters had excellent CVs in the normal range (3.6% to 4.9%). However, Accu-Chek II was found to be more precise in the hypoglycemic and hyperglycemic ranges (3.6% and 2.6%, respectively) than either Glucometer II (8.8% and 5.4%) or Glucoscan 2000 (7.8% and 8.2%). The results of this study indicate that all of the meters and reagent strips tested are highly accurate in determining blood glucose concentrations in the dog. However, both in terms of accuracy and reproducibility of results, Accu-Chek II and Chemstrip bG, gave the highest correlation coefficients and, as such, are probably of the greatest clinical value. 相似文献
44.
Cisplatin Therapy in 41 Dogs With Malignant Tumors 总被引:3,自引:0,他引:3
Deborah W. Knapp DVM Ralph C. Richardson DVM Patty L. Bonney BS RVT Kevin Hahn DVM 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1988,2(1):41-46
Forty-one dogs with a variety of histopathologically diagnosed, measurable tumors were treated with cisplatin (cis-diamminedichloroplatinum, Platinol, Bristol Laboratories, Syracuse, NY 13221-4755) as a single agent at a dosage of 60 mg/m2 given intravenously at 3-week intervals. In an attempt to avoid renal toxicity of cisplatin, saline diuresis was induced and maintained for 4 hours before and 2 hours following cisplatin administration. The dogs received one to ten doses of cisplatin. To determine response to therapy and to monitor toxicity of the drug, the dogs were evaluated with physical examinations including tumor measurements, radiography, complete blood counts, platelet counts, urinalyses, serum urea nitrogen concentrations, and serum creatinine concentrations. An overall response rate of 19% was observed. Complete remission occurred in one of 11 dogs with squamous cell carcinomas and one of one dog with a mediastinal undifferentiated carcinoma. Partial remissions were documented in one of 11 dogs with squamous cell carcinomas, two of three dogs with metastatic osteosarcomas, one of three dogs with nasal adenocarcinomas, and one of one dog with a thyroid adenocarcinoma. Toxic side effects were primarily gastrointestinal in nature, with vomiting occurring 1-6 hours after cisplatin administration in 27 of 41 dogs. Severe anorexia occurred in three dogs, and hemorrhagic diarrhea was observed in one dog. One dog developed grand mal seizures and died 3 hours following therapy. Granulocytopenia was documented in six dogs, and thrombocytopenia was observed in four dogs. One dog showed an increase in serum urea nitrogen and creatinine concentrations, but this patient had known pre-existing renal disease.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
45.
Pasteurella haemolytica was found to be the cause of acute mastitis, toxemia, and disseminated intravascular coagulopathy in a cow. Intensive treatment with antibiotics and fluid and heparin administration failed to reverse the progression of the disease, and death resulted. Necropsy revealed extensive evidence of consumptive coagulopathy, as well as mastitis. Pasteurella haemolytica rarely has been implicated as a cause of mastitis in cows. 相似文献
46.
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48.
Lyndell Levitt BS DVM J. David Fowler BS DVM MVSc 《Veterinary radiology & ultrasound》1988,29(3):129-132
An 8-year-old male Labrador retriever presented with a rear limb lameness cased by an osteolytic lesion of the left acetabulum and femoral head and neck. Initial bone biopsy study was nondiagnostic. Histopathologic study and culture of the subsequently excised femoral head and neck revealed a Staphyloccocus intermedial arthritis and osteomyelitis. Neoplash was ruled out on the basis of histopathologic analysis. 相似文献
49.
V.B. Meacham BS 《Journal of Equine Veterinary Science》1984,4(5):210-214
Mineral metabolism in the equine is a complex process involving absorption sites and interactions between the minerals themselves and other compounds. Factors such as the digestibility of the minerals and the extent of the interactions all play an important role in the mineral amounts required in the diet.Inadequate levels of minerals in the diet can lead to physiological maladies such as HNS and Ricketts. A knowledge and understanding of mineral metabolism is essential to the success of equine management. 相似文献
50.